Overview

Dataset statistics

Number of variables42
Number of observations1118895
Missing cells0
Missing cells (%)0.0%
Duplicate rows641
Duplicate rows (%)0.1%
Total size in memory351.1 MiB
Average record size in memory329.0 B

Variable types

CAT41
BOOL1

Warnings

Negative has constant value "1118895" Constant
Dataset has 641 (0.1%) duplicate rows Duplicates
#ID(s) interactor A has a high cardinality: 74355 distinct values High cardinality
ID(s) interactor B has a high cardinality: 92883 distinct values High cardinality
Alt. ID(s) interactor A has a high cardinality: 70060 distinct values High cardinality
Alt. ID(s) interactor B has a high cardinality: 88347 distinct values High cardinality
Alias(es) interactor A has a high cardinality: 74362 distinct values High cardinality
Alias(es) interactor B has a high cardinality: 92894 distinct values High cardinality
Interaction detection method(s) has a high cardinality: 238 distinct values High cardinality
Publication 1st author(s) has a high cardinality: 17589 distinct values High cardinality
Publication Identifier(s) has a high cardinality: 21833 distinct values High cardinality
Taxid interactor A has a high cardinality: 1429 distinct values High cardinality
Taxid interactor B has a high cardinality: 1359 distinct values High cardinality
Interaction type(s) has a high cardinality: 55 distinct values High cardinality
Interaction identifier(s) has a high cardinality: 717430 distinct values High cardinality
Confidence value(s) has a high cardinality: 48668 distinct values High cardinality
Xref(s) interactor A has a high cardinality: 149122 distinct values High cardinality
Xref(s) interactor B has a high cardinality: 207497 distinct values High cardinality
Interaction Xref(s) has a high cardinality: 6290 distinct values High cardinality
Annotation(s) interactor A has a high cardinality: 19228 distinct values High cardinality
Annotation(s) interactor B has a high cardinality: 46360 distinct values High cardinality
Interaction annotation(s) has a high cardinality: 103956 distinct values High cardinality
Host organism(s) has a high cardinality: 1860 distinct values High cardinality
Interaction parameter(s) has a high cardinality: 3145 distinct values High cardinality
Creation date has a high cardinality: 4148 distinct values High cardinality
Update date has a high cardinality: 1606 distinct values High cardinality
Checksum(s) interactor A has a high cardinality: 68073 distinct values High cardinality
Checksum(s) interactor B has a high cardinality: 83524 distinct values High cardinality
Interaction Checksum(s) has a high cardinality: 503579 distinct values High cardinality
Feature(s) interactor A has a high cardinality: 72669 distinct values High cardinality
Feature(s) interactor B has a high cardinality: 68846 distinct values High cardinality
Identification method participant A has a high cardinality: 107 distinct values High cardinality
Identification method participant B has a high cardinality: 115 distinct values High cardinality

Reproduction

Analysis started2020-11-13 19:41:22.740826
Analysis finished2020-11-13 19:43:36.102057
Duration2 minutes and 13.36 seconds
Software versionpandas-profiling v2.9.0
Download configurationconfig.yaml

Variables

#ID(s) interactor A
Categorical

HIGH CARDINALITY

Distinct74355
Distinct (%)6.6%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
uniprotkb:P62259
 
18984
uniprotkb:Q5S007
 
4488
uniprotkb:P13569
 
3721
uniprotkb:P03372
 
3454
uniprotkb:P42858
 
2191
Other values (74350)
1086057 
ValueCountFrequency (%) 
uniprotkb:P62259189841.7%
 
uniprotkb:Q5S00744880.4%
 
uniprotkb:P1356937210.3%
 
uniprotkb:P0337234540.3%
 
uniprotkb:P4285821910.2%
 
uniprotkb:P1932020660.2%
 
uniprotkb:P0541219920.2%
 
uniprotkb:P1440419260.2%
 
uniprotkb:Q6P5F917890.2%
 
uniprotkb:P1148417730.2%
 
Other values (74345)107651196.2%
 
2020-11-13T20:45:55.162046image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique22097 ?
Unique (%)2.0%
2020-11-13T20:45:55.393857image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length33
Median length16
Mean length16.31294089
Min length10

ID(s) interactor B
Categorical

HIGH CARDINALITY

Distinct92883
Distinct (%)8.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
uniprotkb:P42858
 
4781
uniprotkb:P11484
 
2725
uniprotkb:P10592
 
1976
uniprotkb:P10591
 
1676
uniprotkb:P54253
 
1525
Other values (92878)
1106212 
ValueCountFrequency (%) 
uniprotkb:P4285847810.4%
 
uniprotkb:P1148427250.2%
 
uniprotkb:P1059219760.2%
 
uniprotkb:P1059116760.1%
 
uniprotkb:P5425315250.1%
 
uniprotkb:P3258911870.1%
 
uniprotkb:P0506711560.1%
 
uniprotkb:P028299400.1%
 
uniprotkb:O005609300.1%
 
uniprotkb:Q96HA88960.1%
 
Other values (92873)110110398.4%
 
2020-11-13T20:45:55.741684image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique28583 ?
Unique (%)2.6%
2020-11-13T20:45:55.893462image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length33
Median length16
Mean length16.3130678
Min length1

Alt. ID(s) interactor A
Categorical

HIGH CARDINALITY

Distinct70060
Distinct (%)6.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
27045
intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631
 
18984
intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9
 
4488
intact:EBI-349854|uniprotkb:Q20BG8|uniprotkb:Q20BH2|uniprotkb:Q2I0A1|uniprotkb:Q2I102
 
3721
intact:EBI-78473|uniprotkb:Q5T5H7|uniprotkb:Q6MZQ9|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7
 
3454
Other values (70055)
1061203 
ValueCountFrequency (%) 
-270452.4%
 
intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631189841.7%
 
intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX944880.4%
 
intact:EBI-349854|uniprotkb:Q20BG8|uniprotkb:Q20BH2|uniprotkb:Q2I0A1|uniprotkb:Q2I10237210.3%
 
intact:EBI-78473|uniprotkb:Q5T5H7|uniprotkb:Q6MZQ9|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS734540.3%
 
intact:EBI-466029|uniprotkb:Q9UQB721910.2%
 
intact:EBI-6189824|uniprotkb:B4DKS4|uniprotkb:E9PDD1|uniprotkb:A8K6R7|uniprotkb:Q6NUP820660.2%
 
intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM719920.2%
 
intact:EBI-1994523|uniprotkb:G3UWT0|uniprotkb:Q9Z1L819260.2%
 
intact:EBI-255023617890.2%
 
Other values (70050)105123994.0%
 
2020-11-13T20:45:56.212415image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique18971 ?
Unique (%)1.7%
2020-11-13T20:45:56.357031image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length4618
Median length50
Mean length63.066277
Min length1

Alt. ID(s) interactor B
Categorical

HIGH CARDINALITY

Distinct88347
Distinct (%)7.9%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
16150
intact:EBI-466029|uniprotkb:Q9UQB7
 
4781
intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-29890
 
2725
intact:EBI-8603|uniprotkb:D6VXY0
 
1976
intact:EBI-8591|uniprotkb:D6VPL2
 
1676
Other values (88342)
1091587 
ValueCountFrequency (%) 
-161501.4%
 
intact:EBI-466029|uniprotkb:Q9UQB747810.4%
 
intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-2989027250.2%
 
intact:EBI-8603|uniprotkb:D6VXY019760.2%
 
intact:EBI-8591|uniprotkb:D6VPL216760.1%
 
intact:EBI-930964|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|uniprotkb:Q17S0215250.1%
 
intact:EBI-8648|uniprotkb:D6W3R111870.1%
 
intact:EBI-77613|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ5811560.1%
 
intact:EBI-8659|uniprotkb:D6W3D19400.1%
 
intact:EBI-727004|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|dip:DIP-42705N|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:B2R5Q79300.1%
 
Other values (88337)108584997.0%
 
2020-11-13T20:45:56.748775image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique25310 ?
Unique (%)2.3%
2020-11-13T20:45:56.915279image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length4618
Median length50
Mean length65.86537879
Min length1

Alias(es) interactor A
Categorical

HIGH CARDINALITY

Distinct74362
Distinct (%)6.6%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)
 
18984
psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym)
 
4488
psi-mi:cftr_human(display_long)|uniprotkb:cAMP-dependent chloride channel(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:CFTR(gene name)|psi-mi:CFTR(display_short)|uniprotkb:ABCC7(gene name synonym)
 
3721
psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)
 
3454
psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)
 
2191
Other values (74357)
1086057 
ValueCountFrequency (%) 
psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)189841.7%
 
psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym)44880.4%
 
psi-mi:cftr_human(display_long)|uniprotkb:cAMP-dependent chloride channel(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:CFTR(gene name)|psi-mi:CFTR(display_short)|uniprotkb:ABCC7(gene name synonym)37210.3%
 
psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)34540.3%
 
psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)21910.2%
 
psi-mi:vcam1_human(display_long)|uniprotkb:VCAM1(gene name)|psi-mi:VCAM1(display_short)|uniprotkb:INCAM-100(gene name synonym)20660.2%
 
psi-mi:jun_human(display_long)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)19920.2%
 
psi-mi:mecom_mouse(display_long)|uniprotkb:Mds1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein homolog(gene name synonym)|uniprotkb:Mecom(gene name)|psi-mi:Mecom(display_short)|uniprotkb:Evi1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:Prdm3(gene name synonym)19260.2%
 
psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)17890.2%
 
psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym)17730.2%
 
Other values (74352)107651196.2%
 
2020-11-13T20:45:57.333784image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique22100 ?
Unique (%)2.0%
2020-11-13T20:45:57.492351image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length17832
Median length197
Mean length224.6818432
Min length22

Alias(es) interactor B
Categorical

HIGH CARDINALITY

Distinct92894
Distinct (%)8.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)
 
4781
psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym)
 
2725
psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short)
 
1976
psi-mi:hsp71_yeast(display_long)|uniprotkb:Heat shock protein YG100(gene name synonym)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short)
 
1676
psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)
 
1525
Other values (92889)
1106212 
ValueCountFrequency (%) 
psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym)47810.4%
 
psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym)27250.2%
 
psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short)19760.2%
 
psi-mi:hsp71_yeast(display_long)|uniprotkb:Heat shock protein YG100(gene name synonym)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short)16760.1%
 
psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym)15250.1%
 
psi-mi:hsp7f_yeast(display_long)|uniprotkb:Chaperone protein MSI3(gene name synonym)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)11870.1%
 
psi-mi:a4_human(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)11560.1%
 
psi-mi:hsp82_yeast(display_long)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)9400.1%
 
psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)9300.1%
 
psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym)8960.1%
 
Other values (92884)110110398.4%
 
2020-11-13T20:45:58.030204image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique28592 ?
Unique (%)2.6%
2020-11-13T20:45:58.753022image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length18257
Median length206
Mean length230.8483754
Min length1

Interaction detection method(s)
Categorical

HIGH CARDINALITY

Distinct238
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0007"(anti tag coimmunoprecipitation)
194787 
psi-mi:"MI:0397"(two hybrid array)
144495 
psi-mi:"MI:0676"(tandem affinity purification)
123586 
psi-mi:"MI:1356"(validated two hybrid)
92417 
psi-mi:"MI:0096"(pull down)
89930 
Other values (233)
473680 
ValueCountFrequency (%) 
psi-mi:"MI:0007"(anti tag coimmunoprecipitation)19478717.4%
 
psi-mi:"MI:0397"(two hybrid array)14449512.9%
 
psi-mi:"MI:0676"(tandem affinity purification)12358611.0%
 
psi-mi:"MI:1356"(validated two hybrid)924178.3%
 
psi-mi:"MI:0096"(pull down)899308.0%
 
psi-mi:"MI:1112"(two hybrid prey pooling approach)754336.7%
 
psi-mi:"MI:0018"(two hybrid)718046.4%
 
psi-mi:"MI:0006"(anti bait coimmunoprecipitation)475874.3%
 
psi-mi:"MI:0398"(two hybrid pooling approach)450594.0%
 
psi-mi:"MI:0432"(one hybrid)272552.4%
 
Other values (228)20654218.5%
 
2020-11-13T20:45:58.918009image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique12 ?
Unique (%)< 0.1%
2020-11-13T20:45:59.072595image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length84
Median length44
Mean length40.81746991
Min length22

Publication 1st author(s)
Categorical

HIGH CARDINALITY

Distinct17589
Distinct (%)1.6%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
Luck et al. (2017)
162719 
Huttlin et al. (2017)
 
58281
Haenig et al. (2020)
 
47294
Rolland et al. (2014)
 
43482
Hein et al. (2015)
 
30477
Other values (17584)
776642 
ValueCountFrequency (%) 
Luck et al. (2017)16271914.5%
 
Huttlin et al. (2017)582815.2%
 
Haenig et al. (2020)472944.2%
 
Rolland et al. (2014)434823.9%
 
Hein et al. (2015)304772.7%
 
Krogan et al. (2006)265742.4%
 
Gavin et al. (2006)261022.3%
 
Gong et al. (2009)223492.0%
 
Fuxman et al. (2016)219542.0%
 
Kislinger et al. (2006)215331.9%
 
Other values (17579)65813058.8%
 
2020-11-13T20:45:59.257633image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique2778 ?
Unique (%)0.2%
2020-11-13T20:45:59.410536image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length38
Median length19
Mean length19.6592969
Min length1

Publication Identifier(s)
Categorical

HIGH CARDINALITY

Distinct21833
Distinct (%)2.0%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
pubmed:32296183|imex:IM-25472
162719 
pubmed:28514442|doi:10.1038/nature22366|imex:IM-25778
 
58281
pubmed:32814053|imex:IM-28217|doi:10.1016/j.celrep.2020.108050
 
47294
imex:IM-23318|pubmed:25416956
 
43482
pubmed:26496610|imex:IM-24272
 
30477
Other values (21828)
776642 
ValueCountFrequency (%) 
pubmed:32296183|imex:IM-2547216271914.5%
 
pubmed:28514442|doi:10.1038/nature22366|imex:IM-25778582815.2%
 
pubmed:32814053|imex:IM-28217|doi:10.1016/j.celrep.2020.108050472944.2%
 
imex:IM-23318|pubmed:25416956434823.9%
 
pubmed:26496610|imex:IM-24272304772.7%
 
pubmed:16554755|imex:IM-15332|mint:MINT-5218454265742.4%
 
pubmed:16429126261022.3%
 
pubmed:19536198223302.0%
 
pubmed:27777270|imex:IM-25647219542.0%
 
pubmed:16615898|mint:MINT-5218505215331.9%
 
Other values (21823)65814958.8%
 
2020-11-13T20:45:59.593049image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique3686 ?
Unique (%)0.3%
2020-11-13T20:45:59.743647image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length102
Median length29
Mean length36.57352477
Min length13

Taxid interactor A
Categorical

HIGH CARDINALITY

Distinct1429
Distinct (%)0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
taxid:9606(human)|taxid:9606(Homo sapiens)
603553 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)
137067 
taxid:10090(mouse)|taxid:10090(Mus musculus)
78330 
taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")
 
56991
taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")
 
52085
Other values (1424)
190869 
ValueCountFrequency (%) 
taxid:9606(human)|taxid:9606(Homo sapiens)60355353.9%
 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)13706712.3%
 
taxid:10090(mouse)|taxid:10090(Mus musculus)783307.0%
 
taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")569915.1%
 
taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")520854.7%
 
taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)436213.9%
 
taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")285372.6%
 
taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")221832.0%
 
taxid:192222(camje)|taxid:192222("Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)")123621.1%
 
taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")85610.8%
 
Other values (1419)756056.8%
 
2020-11-13T20:45:59.895291image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique351 ?
Unique (%)< 0.1%
2020-11-13T20:46:00.053817image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length189
Median length42
Mean length51.02948981
Min length31

Taxid interactor B
Categorical

HIGH CARDINALITY

Distinct1359
Distinct (%)0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
taxid:9606(human)|taxid:9606(Homo sapiens)
660309 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)
137342 
taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")
 
57082
taxid:10090(mouse)|taxid:10090(Mus musculus)
 
56410
taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")
 
52144
Other values (1354)
155608 
ValueCountFrequency (%) 
taxid:9606(human)|taxid:9606(Homo sapiens)66030959.0%
 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)13734212.3%
 
taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")570825.1%
 
taxid:10090(mouse)|taxid:10090(Mus musculus)564105.0%
 
taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")521444.7%
 
taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)436683.9%
 
taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")290722.6%
 
taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")142411.3%
 
taxid:192222(camje)|taxid:192222("Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)")125851.1%
 
taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)")37880.3%
 
Other values (1349)522544.7%
 
2020-11-13T20:46:00.213442image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique355 ?
Unique (%)< 0.1%
2020-11-13T20:46:00.369972image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length189
Median length42
Mean length49.77514691
Min length1

Interaction type(s)
Categorical

HIGH CARDINALITY

Distinct55
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0915"(physical association)
635729 
psi-mi:"MI:0914"(association)
406883 
psi-mi:"MI:0407"(direct interaction)
 
37128
psi-mi:"MI:0403"(colocalization)
 
30887
psi-mi:"MI:0217"(phosphorylation reaction)
 
3794
Other values (50)
 
4474
ValueCountFrequency (%) 
psi-mi:"MI:0915"(physical association)63572956.8%
 
psi-mi:"MI:0914"(association)40688336.4%
 
psi-mi:"MI:0407"(direct interaction)371283.3%
 
psi-mi:"MI:0403"(colocalization)308872.8%
 
psi-mi:"MI:0217"(phosphorylation reaction)37940.3%
 
psi-mi:"MI:0220"(ubiquitination reaction)6810.1%
 
psi-mi:"MI:0203"(dephosphorylation reaction)5680.1%
 
psi-mi:"MI:0570"(protein cleavage)545< 0.1%
 
psi-mi:"MI:0213"(methylation reaction)348< 0.1%
 
psi-mi:"MI:0414"(enzymatic reaction)341< 0.1%
 
Other values (45)19910.2%
 
2020-11-13T20:46:00.527421image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique5 ?
Unique (%)< 0.1%
2020-11-13T20:46:00.779848image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length68
Median length38
Mean length34.51186036
Min length29
Distinct26
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0469"(IntAct)
894227 
psi-mi:"MI:0471"(MINT)
136724 
psi-mi:"MI:0465"(DIP)
 
46627
psi-mi:"MI:0486"(UniProt)
 
26336
psi-mi:"MI:1335"(HPIDb)
 
5062
Other values (21)
 
9919
ValueCountFrequency (%) 
psi-mi:"MI:0469"(IntAct)89422779.9%
 
psi-mi:"MI:0471"(MINT)13672412.2%
 
psi-mi:"MI:0465"(DIP)466274.2%
 
psi-mi:"MI:0486"(UniProt)263362.4%
 
psi-mi:"MI:1335"(HPIDb)50620.5%
 
psi-mi:"MI:1332"(bhf-ucl)40250.4%
 
psi-mi:"MI:0903"(mpidb)17500.2%
 
psi-mi:"MI:1262"(I2D)11790.1%
 
psi-mi:"MI:0974"(InnateDB)8520.1%
 
psi-mi:"MI:0917"(matrixdb)6900.1%
 
Other values (16)14230.1%
 
2020-11-13T20:46:00.904517image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique1 ?
Unique (%)< 0.1%
2020-11-13T20:46:01.030575image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length39
Median length24
Mean length23.65740306
Min length20

Interaction identifier(s)
Categorical

HIGH CARDINALITY

Distinct717430
Distinct (%)64.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
intact:EBI-21364596|imex:IM-26684-50
 
1803
intact:EBI-21360986|imex:IM-26684-48
 
1803
intact:EBI-8401905|mint:MINT-4409852
 
1561
intact:EBI-21302175|imex:IM-26954-3
 
1423
intact:EBI-8412660|mint:MINT-4409856
 
1349
Other values (717425)
1110956 
ValueCountFrequency (%) 
intact:EBI-21364596|imex:IM-26684-5018030.2%
 
intact:EBI-21360986|imex:IM-26684-4818030.2%
 
intact:EBI-8401905|mint:MINT-440985215610.1%
 
intact:EBI-21302175|imex:IM-26954-314230.1%
 
intact:EBI-8412660|mint:MINT-440985613490.1%
 
intact:EBI-21301141|imex:IM-26954-112960.1%
 
intact:EBI-8312518|mint:MINT-440981012480.1%
 
intact:EBI-8392519|mint:MINT-440985012150.1%
 
intact:EBI-8419242|mint:MINT-440986010880.1%
 
intact:EBI-8429350|mint:MINT-440986210850.1%
 
Other values (717420)110502498.8%
 
2020-11-13T20:46:03.355940image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique681021 ?
Unique (%)60.9%
2020-11-13T20:46:03.515568image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length650
Median length37
Mean length36.96389474
Min length14

Confidence value(s)
Categorical

HIGH CARDINALITY

Distinct48668
Distinct (%)4.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
intact-miscore:0.35
342555 
intact-miscore:0.56
156605 
intact-miscore:0.37
97323 
intact-miscore:0.40
46017 
intact-miscore:0.46
 
19459
Other values (48663)
456936 
ValueCountFrequency (%) 
intact-miscore:0.3534255530.6%
 
intact-miscore:0.5615660514.0%
 
intact-miscore:0.37973238.7%
 
intact-miscore:0.40460174.1%
 
intact-miscore:0.46194591.7%
 
intact-miscore:0.44190231.7%
 
intact-miscore:0.53180551.6%
 
intact-miscore:0.49164841.5%
 
intact-miscore:0.67142281.3%
 
intact-miscore:0.72118121.1%
 
Other values (48658)37733433.7%
 
2020-11-13T20:46:03.779031image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique9771 ?
Unique (%)0.9%
2020-11-13T20:46:03.940597image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length383
Median length19
Mean length24.37777182
Min length1
Distinct2
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
681021 
psi-mi:"MI:1060"(spoke expansion)
437874 
ValueCountFrequency (%) 
-68102160.9%
 
psi-mi:"MI:1060"(spoke expansion)43787439.1%
 
2020-11-13T20:46:04.065264image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique0 ?
Unique (%)0.0%
2020-11-13T20:46:04.139220image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
2020-11-13T20:46:04.232009image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length33
Median length1
Mean length13.52304104
Min length1
Distinct24
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0499"(unspecified role)
1109857 
psi-mi:"MI:0502"(enzyme target)
 
3771
psi-mi:"MI:0501"(enzyme)
 
2766
psi-mi:"MI:0586"(inhibitor)
 
438
psi-mi:"MI:0898"(putative self)
 
378
Other values (19)
 
1685
ValueCountFrequency (%) 
psi-mi:"MI:0499"(unspecified role)110985799.2%
 
psi-mi:"MI:0502"(enzyme target)37710.3%
 
psi-mi:"MI:0501"(enzyme)27660.2%
 
psi-mi:"MI:0586"(inhibitor)438< 0.1%
 
psi-mi:"MI:0898"(putative self)378< 0.1%
 
psi-mi:"MI:0941"(competitor)304< 0.1%
 
psi-mi:"MI:0840"(stimulator)225< 0.1%
 
psi-mi:"MI:0684"(ancillary)203< 0.1%
 
psi-mi:"MI:0682"(cofactor)184< 0.1%
 
psi-mi:"MI:2274"(regulator)175< 0.1%
 
Other values (14)5940.1%
 
2020-11-13T20:46:04.349725image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique1 ?
Unique (%)< 0.1%
2020-11-13T20:46:04.470374image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length37
Median length34
Mean length33.95344246
Min length22
Distinct25
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0499"(unspecified role)
1109057 
psi-mi:"MI:0501"(enzyme)
 
3638
psi-mi:"MI:0502"(enzyme target)
 
2943
psi-mi:"MI:0941"(competitor)
 
874
psi-mi:"MI:0684"(ancillary)
 
572
Other values (20)
 
1811
ValueCountFrequency (%) 
psi-mi:"MI:0499"(unspecified role)110905799.1%
 
psi-mi:"MI:0501"(enzyme)36380.3%
 
psi-mi:"MI:0502"(enzyme target)29430.3%
 
psi-mi:"MI:0941"(competitor)8740.1%
 
psi-mi:"MI:0684"(ancillary)5720.1%
 
psi-mi:"MI:0586"(inhibitor)343< 0.1%
 
-305< 0.1%
 
psi-mi:"MI:0840"(stimulator)252< 0.1%
 
psi-mi:"MI:2274"(regulator)181< 0.1%
 
psi-mi:"MI:0898"(putative self)180< 0.1%
 
Other values (15)550< 0.1%
 
2020-11-13T20:46:04.594094image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique0 ?
Unique (%)0.0%
2020-11-13T20:46:04.716713image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length37
Median length34
Mean length33.93590551
Min length1
Distinct15
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0496"(bait)
543539 
psi-mi:"MI:0498"(prey)
364521 
psi-mi:"MI:0497"(neutral component)
172318 
psi-mi:"MI:0499"(unspecified role)
 
36520
psi-mi:"MI:0584"(fluorescence acceptor)
 
594
Other values (10)
 
1403
ValueCountFrequency (%) 
psi-mi:"MI:0496"(bait)54353948.6%
 
psi-mi:"MI:0498"(prey)36452132.6%
 
psi-mi:"MI:0497"(neutral component)17231815.4%
 
psi-mi:"MI:0499"(unspecified role)365203.3%
 
psi-mi:"MI:0584"(fluorescence acceptor)5940.1%
 
psi-mi:"MI:0684"(ancillary)470< 0.1%
 
psi-mi:"MI:0583"(fluorescence donor)462< 0.1%
 
psi-mi:"MI:0898"(putative self)281< 0.1%
 
psi-mi:"MI:0503"(self)71< 0.1%
 
psi-mi:"MI:2334"(luminescence donor)42< 0.1%
 
Other values (5)77< 0.1%
 
2020-11-13T20:46:04.835252image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique0 ?
Unique (%)0.0%
2020-11-13T20:46:04.942966image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length50
Median length22
Mean length24.41483249
Min length22
Distinct15
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0498"(prey)
542392 
psi-mi:"MI:0496"(bait)
364610 
psi-mi:"MI:0497"(neutral component)
172731 
psi-mi:"MI:0499"(unspecified role)
 
36526
psi-mi:"MI:0684"(ancillary)
 
1002
Other values (10)
 
1634
ValueCountFrequency (%) 
psi-mi:"MI:0498"(prey)54239248.5%
 
psi-mi:"MI:0496"(bait)36461032.6%
 
psi-mi:"MI:0497"(neutral component)17273115.4%
 
psi-mi:"MI:0499"(unspecified role)365263.3%
 
psi-mi:"MI:0684"(ancillary)10020.1%
 
psi-mi:"MI:0583"(fluorescence donor)6010.1%
 
psi-mi:"MI:0584"(fluorescence acceptor)490< 0.1%
 
-305< 0.1%
 
psi-mi:"MI:0898"(putative self)69< 0.1%
 
psi-mi:"MI:2334"(luminescence donor)49< 0.1%
 
Other values (5)120< 0.1%
 
2020-11-13T20:46:05.050677image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique0 ?
Unique (%)0.0%
2020-11-13T20:46:05.160956image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length50
Median length22
Mean length24.41518999
Min length1
Distinct22
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0326"(protein)
1086389 
psi-mi:"MI:0328"(small molecule)
 
9606
psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)
 
5296
psi-mi:"MI:0320"(ribonucleic acid)
 
4234
psi-mi:"MI:0319"(deoxyribonucleic acid)
 
3618
Other values (17)
 
9752
ValueCountFrequency (%) 
psi-mi:"MI:0326"(protein)108638997.1%
 
psi-mi:"MI:0328"(small molecule)96060.9%
 
psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)52960.5%
 
psi-mi:"MI:0320"(ribonucleic acid)42340.4%
 
psi-mi:"MI:0319"(deoxyribonucleic acid)36180.3%
 
psi-mi:"MI:0327"(peptide)24060.2%
 
psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)18540.2%
 
psi-mi:"MI:0250"(gene)18410.2%
 
psi-mi:"MI:2204"(micro rna)8940.1%
 
psi-mi:"MI:0608"(ribosomal rna)7690.1%
 
Other values (12)19880.2%
 
2020-11-13T20:46:05.280636image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique0 ?
Unique (%)0.0%
2020-11-13T20:46:05.504038image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length55
Median length25
Mean length25.35176044
Min length22
Distinct25
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0326"(protein)
1087727 
psi-mi:"MI:0319"(deoxyribonucleic acid)
 
24622
psi-mi:"MI:0250"(gene)
 
1970
psi-mi:"MI:0324"(messenger rna)
 
686
psi-mi:"MI:0327"(peptide)
 
583
Other values (20)
 
3307
ValueCountFrequency (%) 
psi-mi:"MI:0326"(protein)108772797.2%
 
psi-mi:"MI:0319"(deoxyribonucleic acid)246222.2%
 
psi-mi:"MI:0250"(gene)19700.2%
 
psi-mi:"MI:0324"(messenger rna)6860.1%
 
psi-mi:"MI:0327"(peptide)5830.1%
 
psi-mi:"MI:0609"(small nucleolar rna)486< 0.1%
 
psi-mi:"MI:0608"(ribosomal rna)455< 0.1%
 
psi-mi:"MI:0328"(small molecule)326< 0.1%
 
-305< 0.1%
 
psi-mi:"MI:1302"(stable complex)295< 0.1%
 
Other values (15)14400.1%
 
2020-11-13T20:46:05.625764image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique1 ?
Unique (%)< 0.1%
2020-11-13T20:46:05.742796image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length55
Median length25
Mean length25.32626565
Min length1

Xref(s) interactor A
Categorical

HIGH CARDINALITY

Distinct149122
Distinct (%)13.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
28703
go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0099400"(caveola neck)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|dip:DIP-29684N|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(ion channel binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR036322|interpro:IPR036770|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|ensembl:ENST00000298910|go:"GO:0016234"(inclusion body)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0007005"(mitochondrion organization)|ensembl:ENSG00000188906|ensembl:ENSP00000298910|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016301"(kinase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043204"(perikaryon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:1903125"(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036479"(peroxidase inhibitor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1903217"(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|interpro:IPR032675|go:"GO:0046039"(GTP metabolic process)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:0030426"(growth cone)|interpro:IPR032171|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0039706"(co-receptor binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:1904713"(beta-catenin destruction complex binding)|go:"GO:1904887"(Wnt signalosome assembly)|reactome:R-HSA-8857538|go:"GO:0007283"(spermatogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021756"(striatum development)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:1904469"|mint:Q5S007|go:"GO:0005902"(microvillus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016310"(phosphorylation)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0097487"(multivesicular body, internal vesicle)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:0000149"(SNARE binding)|go:"GO:0003779"(actin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030276"(clathrin binding)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:0030424"(axon)|rcsb pdb:5MY9|rcsb pdb:5MYC|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0000186"(activation of MAPKK activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0035640"(exploration behavior)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0070997"(neuron death)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|refseq:NP_940980.3|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:2ZEJ|rcsb pdb:3D6T|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6DLO|rcsb pdb:6DLP|go:"GO:0005654"(nucleoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0045121"(membrane raft)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR027417|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005615"(extracellular space)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0003924"(GTPase activity)|go:"GO:0015631"(tubulin binding)
 
4434
reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|mint:P13569|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-HSA-382556|reactome:R-HSA-5627083|reactome:R-HSA-5678895|rcsb pdb:4WZ6|go:"GO:0005829"(cytosol)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|ensembl:ENST00000003084|ensembl:ENSG00000001626|ensembl:ENSP00000003084|rcsb pdb:6O1V|rcsb pdb:6O2P|rcsb pdb:5D3F|dip:DIP-32788N|go:"GO:0017081"(chloride channel regulator activity)|rcsb pdb:5D2D|rcsb pdb:5D3E|go:"GO:0005765"(lysosomal membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0031901"(early endosome membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATPase activity)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|rcsb pdb:5TF7|rcsb pdb:5TF8|rcsb pdb:5TFA|rcsb pdb:5TFB|rcsb pdb:5TFC|rcsb pdb:5TFD|rcsb pdb:5TFF|rcsb pdb:5TFG|rcsb pdb:5TFI|rcsb pdb:5TFJ|rcsb pdb:5TGK|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0061024"(membrane organization)|rcsb pdb:5UAK|go:"GO:0051087"(chaperone binding)|go:"GO:0016853"(isomerase activity)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|rcsb pdb:6GJQ|rcsb pdb:6GJS|rcsb pdb:6GJU|rcsb pdb:6GK4|rcsb pdb:6GKD|reactome:R-HSA-9646399|interpro:IPR036640|interpro:IPR027417|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0106138"(Sec61 translocon complex binding)|rcsb pdb:6HEP|rcsb pdb:6MSM|ensembl:ENSP00000497203|ensembl:ENST00000649781|refseq:NP_000483.3|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|rcsb pdb:1NBD|rcsb pdb:1XMI|rcsb pdb:1XMJ|rcsb pdb:2BBO|rcsb pdb:2BBS|rcsb pdb:2BBT|rcsb pdb:2PZE|rcsb pdb:2PZF|rcsb pdb:2PZG|rcsb pdb:3GD7|rcsb pdb:3ISW|rcsb pdb:2LOB|go:"GO:0005769"(early endosome)|interpro:IPR025837|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)
 
3704
go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:3Q95|rcsb pdb:6OWC|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR024178|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensembl:ENSG00000091831|go:"GO:0005654"(nucleoplasm)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0005496"(steroid binding)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0097550"(transcription preinitiation complex)|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:4AA6|go:"GO:0002064"(epithelial cell development)|go:"GO:0008584"(male gonad development)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|rcsb pdb:5JMM|rcsb pdb:5U2B|interpro:IPR024736|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5T0X|rcsb pdb:5TN9|rcsb pdb:5TNB|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071391"(cellular response to estrogen stimulus)|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|reactome:R-HSA-5689896|reactome:R-HSA-8866910|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6CBZ|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|go:"GO:0000790"(nuclear chromatin)|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:5AK2|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0035327"(transcriptionally active chromatin)|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|ensembl:ENST00000206249|ensembl:ENST00000338799|ensembl:ENST00000440973|ensembl:ENST00000443427|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|refseq:NP_001278159.1|refseq:NP_001278170.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:5U2D|dip:DIP-5965N|go:"GO:0005829"(cytosol)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|rcsb pdb:5UFW|rcsb pdb:5UFX|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|mint:P03372|rcsb pdb:4ZN9|rcsb pdb:4ZN7|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5HYR|reactome:R-HSA-1251985|reactome:R-HSA-383280|rcsb pdb:5AAU|rcsb pdb:5AAV|go:"GO:0051117"(ATPase binding)|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:6CZN|rcsb pdb:6D0F|go:"GO:0001223"(transcription coactivator binding)|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5ACC|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|rcsb pdb:6B0F|rcsb pdb:6CHW|rcsb pdb:6CHZ|reactome:R-HSA-8939211|reactome:R-HSA-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMU|reactome:R-HSA-9009391|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6TL3|rcsb pdb:6VVP|rcsb pdb:5W9C|rcsb pdb:5WGD|rcsb pdb:5WGQ|reactome:R-HSA-4090294|rcsb pdb:6IAR|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|rcsb pdb:5N10|reactome:R-HSA-8931987|reactome:R-HSA-8939256|interpro:IPR035500|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5T1Z|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|rcsb pdb:5W9D|reactome:R-HSA-8939902|go:"GO:0010629"(negative regulation of gene expression)|rcsb pdb:4DMA|go:"GO:0016021"(integral component of membrane)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VNN|rcsb pdb:6VPK|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|rcsb pdb:6C42|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|rcsb pdb:4O6F|refseq:XP_006715438.1|go:"GO:0005794"(Golgi apparatus)|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4XI3
 
3421
go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENST00000294728|ensembl:ENST00000347652|ensembl:ENST00000370119|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000162692|ensembl:ENSP00000294728|ensembl:ENSP00000304611|ensembl:ENSP00000359137|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-877300|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0007160"(cell-matrix adhesion)|reactome:R-HSA-6785807|interpro:IPR013106(Immunoglobulin V-set)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0005178"(integrin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR036179|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0030175"(filopodium)|go:"GO:0005902"(microvillus)|go:"GO:0002102"(podosome)|go:"GO:0030183"(B cell differentiation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0050776"(regulation of immune response)|refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR003989(Vascular cell adhesion molecule-1)|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC
 
2058
Other values (149117)
1076575 
ValueCountFrequency (%) 
-287032.6%
 
go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0099400"(caveola neck)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|dip:DIP-29684N|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(ion channel binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR036322|interpro:IPR036770|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|ensembl:ENST00000298910|go:"GO:0016234"(inclusion body)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0007005"(mitochondrion organization)|ensembl:ENSG00000188906|ensembl:ENSP00000298910|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016301"(kinase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043204"(perikaryon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:1903125"(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036479"(peroxidase inhibitor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1903217"(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|interpro:IPR032675|go:"GO:0046039"(GTP metabolic process)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:0030426"(growth cone)|interpro:IPR032171|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0039706"(co-receptor binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:1904713"(beta-catenin destruction complex binding)|go:"GO:1904887"(Wnt signalosome assembly)|reactome:R-HSA-8857538|go:"GO:0007283"(spermatogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021756"(striatum development)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:1904469"|mint:Q5S007|go:"GO:0005902"(microvillus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016310"(phosphorylation)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0097487"(multivesicular body, internal vesicle)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:0000149"(SNARE binding)|go:"GO:0003779"(actin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030276"(clathrin binding)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:0030424"(axon)|rcsb pdb:5MY9|rcsb pdb:5MYC|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0000186"(activation of MAPKK activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0035640"(exploration behavior)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0070997"(neuron death)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|refseq:NP_940980.3|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:2ZEJ|rcsb pdb:3D6T|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6DLO|rcsb pdb:6DLP|go:"GO:0005654"(nucleoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0045121"(membrane raft)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR027417|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005615"(extracellular space)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0003924"(GTPase activity)|go:"GO:0015631"(tubulin binding)44340.4%
 
reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|mint:P13569|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-HSA-382556|reactome:R-HSA-5627083|reactome:R-HSA-5678895|rcsb pdb:4WZ6|go:"GO:0005829"(cytosol)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|ensembl:ENST00000003084|ensembl:ENSG00000001626|ensembl:ENSP00000003084|rcsb pdb:6O1V|rcsb pdb:6O2P|rcsb pdb:5D3F|dip:DIP-32788N|go:"GO:0017081"(chloride channel regulator activity)|rcsb pdb:5D2D|rcsb pdb:5D3E|go:"GO:0005765"(lysosomal membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0031901"(early endosome membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATPase activity)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|rcsb pdb:5TF7|rcsb pdb:5TF8|rcsb pdb:5TFA|rcsb pdb:5TFB|rcsb pdb:5TFC|rcsb pdb:5TFD|rcsb pdb:5TFF|rcsb pdb:5TFG|rcsb pdb:5TFI|rcsb pdb:5TFJ|rcsb pdb:5TGK|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0061024"(membrane organization)|rcsb pdb:5UAK|go:"GO:0051087"(chaperone binding)|go:"GO:0016853"(isomerase activity)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|rcsb pdb:6GJQ|rcsb pdb:6GJS|rcsb pdb:6GJU|rcsb pdb:6GK4|rcsb pdb:6GKD|reactome:R-HSA-9646399|interpro:IPR036640|interpro:IPR027417|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0106138"(Sec61 translocon complex binding)|rcsb pdb:6HEP|rcsb pdb:6MSM|ensembl:ENSP00000497203|ensembl:ENST00000649781|refseq:NP_000483.3|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|rcsb pdb:1NBD|rcsb pdb:1XMI|rcsb pdb:1XMJ|rcsb pdb:2BBO|rcsb pdb:2BBS|rcsb pdb:2BBT|rcsb pdb:2PZE|rcsb pdb:2PZF|rcsb pdb:2PZG|rcsb pdb:3GD7|rcsb pdb:3ISW|rcsb pdb:2LOB|go:"GO:0005769"(early endosome)|interpro:IPR025837|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport)37040.3%
 
go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:3Q95|rcsb pdb:6OWC|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR024178|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensembl:ENSG00000091831|go:"GO:0005654"(nucleoplasm)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0005496"(steroid binding)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0097550"(transcription preinitiation complex)|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:4AA6|go:"GO:0002064"(epithelial cell development)|go:"GO:0008584"(male gonad development)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|rcsb pdb:5JMM|rcsb pdb:5U2B|interpro:IPR024736|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5T0X|rcsb pdb:5TN9|rcsb pdb:5TNB|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071391"(cellular response to estrogen stimulus)|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|reactome:R-HSA-5689896|reactome:R-HSA-8866910|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6CBZ|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|go:"GO:0000790"(nuclear chromatin)|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:5AK2|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0035327"(transcriptionally active chromatin)|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|ensembl:ENST00000206249|ensembl:ENST00000338799|ensembl:ENST00000440973|ensembl:ENST00000443427|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|refseq:NP_001278159.1|refseq:NP_001278170.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:5U2D|dip:DIP-5965N|go:"GO:0005829"(cytosol)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|rcsb pdb:5UFW|rcsb pdb:5UFX|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|mint:P03372|rcsb pdb:4ZN9|rcsb pdb:4ZN7|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5HYR|reactome:R-HSA-1251985|reactome:R-HSA-383280|rcsb pdb:5AAU|rcsb pdb:5AAV|go:"GO:0051117"(ATPase binding)|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:6CZN|rcsb pdb:6D0F|go:"GO:0001223"(transcription coactivator binding)|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5ACC|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|rcsb pdb:6B0F|rcsb pdb:6CHW|rcsb pdb:6CHZ|reactome:R-HSA-8939211|reactome:R-HSA-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMU|reactome:R-HSA-9009391|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6TL3|rcsb pdb:6VVP|rcsb pdb:5W9C|rcsb pdb:5WGD|rcsb pdb:5WGQ|reactome:R-HSA-4090294|rcsb pdb:6IAR|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|rcsb pdb:5N10|reactome:R-HSA-8931987|reactome:R-HSA-8939256|interpro:IPR035500|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5T1Z|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|rcsb pdb:5W9D|reactome:R-HSA-8939902|go:"GO:0010629"(negative regulation of gene expression)|rcsb pdb:4DMA|go:"GO:0016021"(integral component of membrane)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VNN|rcsb pdb:6VPK|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|rcsb pdb:6C42|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|rcsb pdb:4O6F|refseq:XP_006715438.1|go:"GO:0005794"(Golgi apparatus)|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4XI334210.3%
 
go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENST00000294728|ensembl:ENST00000347652|ensembl:ENST00000370119|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000162692|ensembl:ENSP00000294728|ensembl:ENSP00000304611|ensembl:ENSP00000359137|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-877300|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0007160"(cell-matrix adhesion)|reactome:R-HSA-6785807|interpro:IPR013106(Immunoglobulin V-set)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0005178"(integrin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR036179|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0030175"(filopodium)|go:"GO:0005902"(microvillus)|go:"GO:0002102"(podosome)|go:"GO:0030183"(B cell differentiation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0050776"(regulation of immune response)|refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR003989(Vascular cell adhesion molecule-1)|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC20580.2%
 
dip:DIP-46516N|refseq:NP_067417.1|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSMUSG00000027684|ensembl:ENSMUSP00000103905|reactome:R-MMU-3214841|mint:P14404|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030900"(forebrain development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060039"(pericardium development)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0098727"(maintenance of cell number)|reactome:R-MMU-8943724|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|ensembl:ENSMUST00000108270|go:"GO:0016607"(nuclear speck)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070828"(heterochromatin organization)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030097"(hemopoiesis)|interpro:IPR036236|interpro:IPR001214(SET)|go:"GO:0042803"(protein homodimerization activity)19260.2%
 
go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035976"(transcription factor AP-1 complex)|refseq:NP_002219.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:1902895"(positive regulation of pri-miRNA transcription by RNA polymerase II)|ensembl:ENST00000371222|reactome:R-HSA-9018519|go:"GO:0003713"(transcription coactivator activity)|dip:DIP-5961N|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0001102"(RNA polymerase II activating transcription factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0007265"(Ras protein signal transduction)|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5687128|ensembl:ENSG00000177606|ensembl:ENSP00000360266|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:0000976"(transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-HSA-6796648|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|reactome:R-HSA-5617472|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8862803|go:"GO:0005719"(nuclear euchromatin)|go:"GO:0035497"(cAMP response element binding)|reactome:R-HSA-9673324|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-8943724|go:"GO:0000790"(nuclear chromatin)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0010033"(response to organic substance)|go:"GO:0006366"(transcription by RNA polymerase II)|rcsb pdb:5FV8|go:"GO:0019899"(enzyme binding)|mint:P05412|go:"GO:0001525"(angiogenesis)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0042493"(response to drug)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|rcsb pdb:5T01|go:"GO:0005634"(nucleus)|psi-mi:"MI:0326"(protein)18450.2%
 
go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0046825"(regulation of protein export from nucleus)|refseq:NP_001030303.1|refseq:NP_598775.2|ensembl:ENSMUSG00000020290|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR001494(Importin-beta, N-terminal)|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|ensembl:ENSMUST00000109551|go:"GO:0000776"(kinetochore)|ensembl:ENSMUST00000020538|ensembl:ENSMUST00000102869|ensembl:ENSMUST00000102870|dip:DIP-48612N|reactome:R-MMU-68877|go:"GO:0032991"(protein-containing complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR040485|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-69273|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178|reactome:R-MMU-141444|reactome:R-MMU-5687128|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0015030"(Cajal body)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0008536"(Ran GTPase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005829"(cytosol)|refseq:XP_006514493.1|go:"GO:0005737"(cytoplasm)|interpro:IPR041123|interpro:IPR041235|reactome:R-MMU-9634638|reactome:R-MMU-9648025|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0042493"(response to drug)17830.2%
 
go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding)17710.2%
 
go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding)16580.1%
 
Other values (149112)106759295.4%
 
2020-11-13T20:46:07.437276image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique86223 ?
Unique (%)7.7%
2020-11-13T20:46:07.589839image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length16239
Median length807
Mean length1318.134188
Min length1

Xref(s) interactor B
Categorical

HIGH CARDINALITY

Distinct207497
Distinct (%)18.5%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
29283
go:"GO:0005776"(autophagosome)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005770"(late endosome)|go:"GO:0005634"(nucleus)|reactome:R-HSA-9022692|go:"GO:0019900"(kinase binding)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6EZ8|go:"GO:0042297"(vocal learning)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0034452"(dynactin binding)|go:"GO:0005814"(centriole)|go:"GO:0045724"(positive regulation of cilium assembly)|ensembl:ENST00000355072|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0044325"(ion channel binding)|ensembl:ENSG00000197386|ensembl:ENSP00000347184|go:"GO:0005522"(profilin binding)|dip:DIP-32492N|mint:P42858|go:"GO:0005654"(nucleoplasm)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0007030"(Golgi organization)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0047496"(vesicle transport along microtubule)|rcsb pdb:2D3X|refseq:NP_002102.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000091(Huntingtin)|interpro:IPR024613|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0016234"(inclusion body)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|rcsb pdb:6N8C|go:"GO:0005769"(early endosome)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|go:"GO:0006915"(apoptotic process)|interpro:IPR028426|rcsb pdb:2LD0|rcsb pdb:2LD2|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048487"(beta-tubulin binding)|entrezgene/locuslink:3064(identity)
 
4464
go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding)
 
2721
go:"GO:0005829"(cytosol)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_013076.1|sgd:S000003947|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-SCE-8856828|mint:P10592|dip:DIP-2265N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0000049"(tRNA binding)|go:"GO:0035719"(tRNA import into nucleus)|interpro:IPR029047|interpro:IPR029048|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|go:"GO:0016887"(ATPase activity)|go:"GO:0051082"(unfolded protein binding)
 
1973
go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding)
 
1636
Other values (207492)
1078818 
ValueCountFrequency (%) 
-292832.6%
 
go:"GO:0005776"(autophagosome)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005770"(late endosome)|go:"GO:0005634"(nucleus)|reactome:R-HSA-9022692|go:"GO:0019900"(kinase binding)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6EZ8|go:"GO:0042297"(vocal learning)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0034452"(dynactin binding)|go:"GO:0005814"(centriole)|go:"GO:0045724"(positive regulation of cilium assembly)|ensembl:ENST00000355072|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0044325"(ion channel binding)|ensembl:ENSG00000197386|ensembl:ENSP00000347184|go:"GO:0005522"(profilin binding)|dip:DIP-32492N|mint:P42858|go:"GO:0005654"(nucleoplasm)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0007030"(Golgi organization)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0047496"(vesicle transport along microtubule)|rcsb pdb:2D3X|refseq:NP_002102.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000091(Huntingtin)|interpro:IPR024613|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0016234"(inclusion body)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|rcsb pdb:6N8C|go:"GO:0005769"(early endosome)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|go:"GO:0006915"(apoptotic process)|interpro:IPR028426|rcsb pdb:2LD0|rcsb pdb:2LD2|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048487"(beta-tubulin binding)|entrezgene/locuslink:3064(identity)44640.4%
 
go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding)27210.2%
 
go:"GO:0005829"(cytosol)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_013076.1|sgd:S000003947|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-SCE-8856828|mint:P10592|dip:DIP-2265N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0000049"(tRNA binding)|go:"GO:0035719"(tRNA import into nucleus)|interpro:IPR029047|interpro:IPR029048|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|go:"GO:0016887"(ATPase activity)|go:"GO:0051082"(unfolded protein binding)19730.2%
 
go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding)16360.1%
 
go:"GO:0005844"(polysome)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042026"(protein refolding)|refseq:NP_015219.1|sgd:S000006027|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F|mint:P32589|dip:DIP-6645N|go:"GO:0006457"(protein folding)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005516"(calmodulin binding)|go:"GO:0006914"(autophagy)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)11830.1%
 
go:"GO:0005737"(cytoplasm)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0016363"(nuclear matrix)|go:"GO:0005654"(nucleoplasm)|go:"GO:0034046"("poly(G) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051168"(nuclear export)|go:"GO:0006396"(RNA processing)|refseq:NP_000323.2|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0035176"(social behavior)|go:"GO:0003677"(DNA binding)|rcsb pdb:2M41|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000244769|ensembl:ENST00000436367|ensembl:ENSP00000244769|ensembl:ENSP00000416360|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0048856"(anatomical structure development)|mint:P54253|dip:DIP-35353N|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR043404|refseq:NP_001121636.1|ensembl:ENSG00000124788|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR020997|rcsb pdb:1OA8|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR040172|interpro:IPR036096|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|go:"GO:0043621"(protein self-association)|entrezgene/locuslink:6310(identity)11270.1%
 
rcsb pdb:4HIX|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:6OC9|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048143"(astrocyte activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1905945"(regulation of response to calcium ion)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0005109"(frizzled binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007613"(memory)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_000475.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR024329|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR019744|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019745|interpro:IPR019543|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|go:"GO:0030424"(axon)|go:"GO:0009986"(cell surface)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005829"(cytosol)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0003677"(DNA binding)|go:"GO:0008201"(heparin binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0007155"(cell adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0016358"(dendrite development)|go:"GO:0006897"(endocytosis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045087"(innate immune response)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0002576"(platelet degranulation)|go:"GO:0006417"(regulation of translation)|go:"GO:0008542"(visual learning)|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1UO7|rcsb pdb:1UO8|rcsb pdb:1UOA|rcsb pdb:1UOI|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BOM|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:3AYU|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|rcsb pdb:2NAO|rcsb pdb:5BUO|rcsb pdb:5KK3|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|dip:DIP-574N|reactome:R-HSA-381426|reactome:R-HSA-8957275|go:"GO:0032991"(protein-containing complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051425"(PTB domain binding)|rcsb pdb:2MGT|rcsb pdb:2MPZ|rcsb pdb:2MXU|rcsb pdb:4PQD|go:"GO:0005768"(endosome)|rcsb pdb:4JFN|rcsb pdb:4M1C|go:"GO:0005641"(nuclear envelope lumen)|ensembl:ENST00000346798|ensembl:ENST00000348990|ensembl:ENST00000354192|ensembl:ENST00000357903|ensembl:ENST00000358918|ensembl:ENST00000440126|go:"GO:0019899"(enzyme binding)|go:"GO:0045121"(membrane raft)|rcsb pdb:4NGE|go:"GO:0005615"(extracellular space)|rcsb pdb:4ONF|rcsb pdb:4ONG|ensembl:ENSG00000142192|ensembl:ENSP00000284981|ensembl:ENSP00000345463|ensembl:ENSP00000346129|ensembl:ENSP00000350578|ensembl:ENSP00000351796|ensembl:ENSP00000387483|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:5W3P|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:5LFY|mint:P05067|go:"GO:0030900"(forebrain development)|rcsb pdb:5AM8|rcsb pdb:5AMB|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-933542|reactome:R-HSA-977225|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|rcsb pdb:4OJF|rcsb pdb:4PWQ|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:1902715"|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0010288"(response to lead ion)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0001967"(suckling behavior)|go:"GO:0005790"(smooth endoplasmic reticulum)|rcsb pdb:2MVX|rcsb pdb:5C67|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007611"(learning or memory)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050808"(synapse organization)|go:"GO:1905893"(positive regulation of cellular response to thapsigargin)|go:"GO:1905896"(positive regulation of cellular response to tunicamycin)|go:"GO:1905898"(positive regulation of response to endoplasmic reticulum stress)|reactome:R-HSA-8862803|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|go:"GO:0009987"(cellular process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0044304"(main axon)|go:"GO:0045177"(apical part of cell)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051124"(synaptic growth at neuromuscular junction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990761"(growth cone lamellipodium)|go:"GO:1990812"(growth cone filopodium)|rcsb pdb:2MJ1|go:"GO:0045202"(synapse)|rcsb pdb:2LOH|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070851"(growth factor receptor binding)|rcsb pdb:5VOS|rcsb pdb:5LV0|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0042535"|go:"GO:0045080"|go:"GO:0045410"|go:"GO:0050725"|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050890"(cognition)|go:"GO:0055037"(recycling endosome)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903523"(negative regulation of blood circulation)|go:"GO:1904472"(positive regulation of endothelin production)|rcsb pdb:5ONP|rcsb pdb:5ONQ|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028866|go:"GO:0046914"(transition metal ion binding)|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005623"(obsolete cell)|go:"GO:0070555"(response to interleukin-1)|reactome:R-HSA-9609523|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6SHS|rcsb pdb:6ITU|reactome:R-HSA-9660826|rcsb pdb:6RHY|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0048786"(presynaptic active zone)|go:"GO:1902894"(negative regulation of pri-miRNA transcription by RNA polymerase II)|go:"GO:1905606"(regulation of presynapse assembly)|rcsb pdb:6CO3|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:1900221"(regulation of amyloid-beta clearance)|rcsb pdb:6IYC|go:"GO:0000185"(activation of MAPKKK activity)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005769"(early endosome)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0014005"(microglia development)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032640"(tumor necrosis factor production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061903"(positive regulation of 1-phosphatidylinositol-3-kinase activity)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0097645"(amylin binding)|go:"GO:0106003"(amyloid-beta complex)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:1904022"(positive regulation of G protein-coupled receptor internalization)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0007612"(learning)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070206"(protein trimerization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:5MY4|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5OQV|rcsb pdb:5VZY|rcsb pdb:6GFI|go:"GO:0043204"(perikaryon)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071287"(cellular response to manganese ion)|rcsb pdb:5TXD|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2LNQ|rcsb pdb:6OIZ|go:"GO:0044267"(cellular protein metabolic process)|rcsb pdb:5AEF|go:"GO:0001878"(response to yeast)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|rcsb pdb:4MVI|rcsb pdb:4MVK|rcsb pdb:4MVL|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:4XXD|rcsb pdb:5CSZ|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:4MDR|rcsb pdb:3SV1|rcsb pdb:2LLM|rcsb pdb:2LP1|refseq:NP_001129488.1|refseq:NP_001129603.1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|entrezgene/locuslink:351(identity)9590.1%
 
reactome:R-SCE-6798695|go:"GO:0005856"(cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003746"(translation elongation factor activity)|refseq:NP_009676.1|refseq:NP_015405.1|sgd:S000006284|sgd:S000000322|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|rcsb pdb:1F60|rcsb pdb:1G7C|rcsb pdb:1IJE|rcsb pdb:1IJF|rcsb pdb:2B7B|rcsb pdb:2B7C|mint:P02994|dip:DIP-2250N|reactome:R-SCE-8876725|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0006414"(translational elongation)|interpro:IPR031157|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-SCE-156842|reactome:R-SCE-3371511|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006412"(translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:1904408"(melatonin binding)|go:"GO:0005829"(cytosol)|rcsb pdb:5O8W|go:"GO:0005739"(mitochondrion)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0019003"(GDP binding)|interpro:IPR0274178680.1%
 
rcsb pdb:2LSV|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|go:"GO:0005737"(cytoplasm)|go:"GO:0005524"(ATP binding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043248"(proteasome assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|refseq:NP_015084.1|sgd:S000006161|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:2CG9|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:2XD6|rcsb pdb:2WEQ|rcsb pdb:2WER|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|mint:P02829|rcsb pdb:5MGX|dip:DIP-2262N|go:"GO:0042802"(identical protein binding)|go:"GO:0006457"(protein folding)|go:"GO:0051604"(protein maturation)|go:"GO:0032204"(regulation of telomere maintenance)|reactome:R-SCE-8939211|reactome:R-SCE-9009391|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|interpro:IPR036890|interpro:IPR037196|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0009986"(cell surface)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0016887"(ATPase activity)|reactome:R-SCE-9660826|go:"GO:0000492"(box C/D snoRNP assembly)|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|reactome:R-SCE-844456|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:4ASG|go:"GO:0051082"(unfolded protein binding)8640.1%
 
Other values (207487)107381796.0%
 
2020-11-13T20:46:09.330330image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique132725 ?
Unique (%)11.9%
2020-11-13T20:46:09.488908image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length16266
Median length834
Mean length1254.050435
Min length1

Interaction Xref(s)
Categorical

HIGH CARDINALITY

Distinct6290
Distinct (%)0.6%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
833274 
psi-mi:"MI:0469"(intact)
123198 
psi-mi:"MI:0465"(dip)
 
50106
go:"GO:0005634"(nucleus)
 
19105
go:"GO:0031965"(nuclear membrane)
 
12115
Other values (6285)
 
81097
ValueCountFrequency (%) 
-83327474.5%
 
psi-mi:"MI:0469"(intact)12319811.0%
 
psi-mi:"MI:0465"(dip)501064.5%
 
go:"GO:0005634"(nucleus)191051.7%
 
go:"GO:0031965"(nuclear membrane)121151.1%
 
go:"GO:0005739"(mitochondrion)90810.8%
 
psi-mi:"MI:0471"(mint)67930.6%
 
go:"GO:0005829"(cytosol)60870.5%
 
go:"GO:0005792"(obsolete microsome)54660.5%
 
go:"GO:0005737"(cytoplasm)23890.2%
 
Other values (6280)512814.6%
 
2020-11-13T20:46:09.647430image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique3506 ?
Unique (%)0.3%
2020-11-13T20:46:09.787110image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length2159
Median length1
Mean length11.47177707
Min length1

Annotation(s) interactor A
Categorical

HIGH CARDINALITY

Distinct19228
Distinct (%)1.7%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
560936 
comment:This prey protein was expressed using pDEST-AD-CHY2, a low copy number expression vector coding for an N-terminal Gal4 AD tag.
 
33776
comment:This prey protein was expressed using pDEST-AD-AR68, a high copy number expression vector coding for a C-terminal Gal4 AD tag.
 
29060
comment:This prey protein was expressed using pDEST-QZ213, a high copy number expression vector coding for an N-terminal Gal4 AD tag.
 
18981
comment:mint
 
11253
Other values (19223)
464889 
ValueCountFrequency (%) 
-56093650.1%
 
comment:This prey protein was expressed using pDEST-AD-CHY2, a low copy number expression vector coding for an N-terminal Gal4 AD tag.337763.0%
 
comment:This prey protein was expressed using pDEST-AD-AR68, a high copy number expression vector coding for a C-terminal Gal4 AD tag.290602.6%
 
comment:This prey protein was expressed using pDEST-QZ213, a high copy number expression vector coding for an N-terminal Gal4 AD tag.189811.7%
 
comment:mint112531.0%
 
comment:"Stoichiometry: 1.0"79420.7%
 
isoform-comment:No experimental confirmation available.72870.7%
 
comment:mint|comment:homomint39630.4%
 
comment:"DIP protein P03372 original sequence version: 214"|comment:"DIP protein P03372 original sequence version: 139"|comment:"DIP protein P03372 original sequence version: 167"34460.3%
 
spectral count:134070.3%
 
Other values (19218)43884439.2%
 
2020-11-13T20:46:09.978045image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique3708 ?
Unique (%)0.3%
2020-11-13T20:46:10.125649image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length6494
Median length1
Mean length74.51531734
Min length1

Annotation(s) interactor B
Categorical

HIGH CARDINALITY

Distinct46360
Distinct (%)4.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
519058 
comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag.
79995 
comment:"Stoichiometry: 1.0"
 
9324
isoform-comment:No experimental confirmation available.
 
8157
comment:"DIP protein P42858 original sequence version: 148"|comment:"DIP protein P42858 original sequence version: 145"|comment:"DIP protein P42858 original sequence version: 142"|comment:"DIP protein P42858 original sequence version: 157"|comment:"DIP protein P42858 original sequence version: 158"|comment:"DIP protein P42858 original sequence version: 156"
 
4756
Other values (46355)
497605 
ValueCountFrequency (%) 
-51905846.4%
 
comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag.799957.1%
 
comment:"Stoichiometry: 1.0"93240.8%
 
isoform-comment:No experimental confirmation available.81570.7%
 
comment:"DIP protein P42858 original sequence version: 148"|comment:"DIP protein P42858 original sequence version: 145"|comment:"DIP protein P42858 original sequence version: 142"|comment:"DIP protein P42858 original sequence version: 157"|comment:"DIP protein P42858 original sequence version: 158"|comment:"DIP protein P42858 original sequence version: 156"47560.4%
 
comment:mint46600.4%
 
author-confidence:A+46050.4%
 
author-confidence:B-45610.4%
 
isoform-comment:No experimental confirmation available.|comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag.43710.4%
 
author-confidence:130670.3%
 
Other values (46350)47634142.6%
 
2020-11-13T20:46:10.386389image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique22950 ?
Unique (%)2.1%
2020-11-13T20:46:10.530983image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length6494
Median length22
Mean length73.25544667
Min length1

Interaction annotation(s)
Categorical

HIGH CARDINALITY

Distinct103956
Distinct (%)9.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
figure legend:Supplementary Table 9|full coverage:Only protein-protein interactions|curation depth:imex curation
162029 
full coverage:Only protein-protein interactions|curation depth:imex curation
96159 
figure legend:Supplementary table 1|full coverage:Only protein-protein interactions|curation depth:imex curation
 
56486
figure legend:Table S2|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation
 
47188
figure legend:supplementary table 2G|full coverage:Only protein-protein interactions|curation depth:imex curation
 
43234
Other values (103951)
713799 
ValueCountFrequency (%) 
figure legend:Supplementary Table 9|full coverage:Only protein-protein interactions|curation depth:imex curation16202914.5%
 
full coverage:Only protein-protein interactions|curation depth:imex curation961598.6%
 
figure legend:Supplementary table 1|full coverage:Only protein-protein interactions|curation depth:imex curation564865.0%
 
figure legend:Table S2|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation471884.2%
 
figure legend:supplementary table 2G|full coverage:Only protein-protein interactions|curation depth:imex curation432343.9%
 
-408603.7%
 
figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation257822.3%
 
figure legend:Table S2223192.0%
 
figure legend:Dataset EV1|full coverage:Only protein-protein interactions|curation depth:imex curation219542.0%
 
figure legend:ST1|comment:mint215331.9%
 
Other values (103946)58135152.0%
 
2020-11-13T20:46:10.977479image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique81099 ?
Unique (%)7.2%
2020-11-13T20:46:11.231831image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length4865
Median length112
Mean length151.2299733
Min length1

Host organism(s)
Categorical

HIGH CARDINALITY

Distinct1860
Distinct (%)0.2%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
510616 
taxid:-1(in vitro)|taxid:-1(In vitro)
108764 
taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)
105942 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)
62977 
taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)
52651 
Other values (1855)
277945 
ValueCountFrequency (%) 
taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")51061645.6%
 
taxid:-1(in vitro)|taxid:-1(In vitro)1087649.7%
 
taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)1059429.5%
 
taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)629775.6%
 
taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)526514.7%
 
taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)478984.3%
 
taxid:4932(baker's yeast-4l)|taxid:4932(Saccharomyces cerevisiae)244222.2%
 
taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo)150661.3%
 
taxid:562(ecolx)|taxid:562(Escherichia coli)115811.0%
 
taxid:9606(human)|taxid:9606(Homo sapiens)114341.0%
 
Other values (1850)16754415.0%
 
2020-11-13T20:46:11.406442image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique428 ?
Unique (%)< 0.1%
2020-11-13T20:46:11.556013image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length213
Median length72
Mean length69.66244554
Min length17

Interaction parameter(s)
Categorical

HIGH CARDINALITY

Distinct3145
Distinct (%)0.3%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
1113450 
kd:1.2x10^-6(molar)
 
31
kd:3.5x10^-6(molar)
 
25
kd:1.54x10^-7(molar)
 
24
kd:1.0x10^-6(molar)
 
21
Other values (3140)
 
5344
ValueCountFrequency (%) 
-111345099.5%
 
kd:1.2x10^-6(molar)31< 0.1%
 
kd:3.5x10^-6(molar)25< 0.1%
 
kd:1.54x10^-7(molar)24< 0.1%
 
kd:1.0x10^-6(molar)21< 0.1%
 
kd:1.62x10^-8(molar)18< 0.1%
 
kd:2.5x10^-6(molar)18< 0.1%
 
kd:2.0x10^-6(molar)18< 0.1%
 
kd:1.9x10^-6(molar)17< 0.1%
 
kd:3.3x10^-6(molar)17< 0.1%
 
Other values (3135)52560.5%
 
2020-11-13T20:46:11.717782image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique2132 ?
Unique (%)0.2%
2020-11-13T20:46:11.869263image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length176
Median length1
Mean length1.107823344
Min length1

Creation date
Categorical

HIGH CARDINALITY

Distinct4148
Distinct (%)0.4%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
2016/06/21
162830 
2017/07/07
 
58287
2020/09/11
 
47296
2014/11/26
 
43497
2015/06/11
 
30568
Other values (4143)
776417 
ValueCountFrequency (%) 
2016/06/2116283014.6%
 
2017/07/07582875.2%
 
2020/09/11472964.2%
 
2014/11/26434973.9%
 
2015/06/11305682.7%
 
2006/05/29265742.4%
 
2005/12/19262652.3%
 
2011/03/10223592.0%
 
2017/02/09219942.0%
 
2007/03/13215381.9%
 
Other values (4138)65768758.8%
 
2020-11-13T20:46:12.036849image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique98 ?
Unique (%)< 0.1%
2020-11-13T20:46:12.171458image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length10
Median length10
Mean length10
Min length10

Update date
Categorical

HIGH CARDINALITY

Distinct1606
Distinct (%)0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
2014/10/16
369941 
2019/12/13
134367 
2019/07/12
54297 
2020/09/18
 
47251
2017/08/10
 
39393
Other values (1601)
473646 
ValueCountFrequency (%) 
2014/10/1636994133.1%
 
2019/12/1313436712.0%
 
2019/07/12542974.9%
 
2020/09/18472514.2%
 
2017/08/10393933.5%
 
2015/02/14295682.6%
 
2019/12/15278832.5%
 
2018/04/06264902.4%
 
2017/02/24218532.0%
 
2019/05/28155741.4%
 
Other values (1596)35227831.5%
 
2020-11-13T20:46:12.305100image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique50 ?
Unique (%)< 0.1%
2020-11-13T20:46:12.435801image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length10
Median length10
Mean length10
Min length10

Checksum(s) interactor A
Categorical

HIGH CARDINALITY

Distinct68073
Distinct (%)6.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
28052
rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090
 
18984
rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606
 
4488
rogid:iuEu3sctRkxQlQYP4BVxV/u4DaA9606
 
3722
rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606
 
3465
Other values (68068)
1060184 
ValueCountFrequency (%) 
-280522.5%
 
rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090189841.7%
 
rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM960644880.4%
 
rogid:iuEu3sctRkxQlQYP4BVxV/u4DaA960637220.3%
 
rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o960634650.3%
 
rogid:KyttHE2o2fORsw6iTh94LB7QShA960621910.2%
 
rogid:ZgZa+cLeZ2PxFhdxPut2qd7QHVo960620660.2%
 
rogid:zAVYwedHKKdvPPGttBP4XZkbCXA960619920.2%
 
rogid:Atnfs7W0A+kPgdN2fUZ4B0JWB3c1009019290.2%
 
rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI1009017890.2%
 
Other values (68063)105021793.9%
 
2020-11-13T20:46:12.705030image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique17860 ?
Unique (%)1.6%
2020-11-13T20:46:12.840442image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length174
Median length37
Mean length36.50516268
Min length1

Checksum(s) interactor B
Categorical

HIGH CARDINALITY

Distinct83524
Distinct (%)7.5%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
30124
rogid:KyttHE2o2fORsw6iTh94LB7QShA9606
 
4781
rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE559292
 
2725
rogid:FakCbxCBdOtSSqw2C4u76D3opS0559292
 
1976
rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk559292
 
1676
Other values (83519)
1077613 
ValueCountFrequency (%) 
-301242.7%
 
rogid:KyttHE2o2fORsw6iTh94LB7QShA960647810.4%
 
rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE55929227250.2%
 
rogid:FakCbxCBdOtSSqw2C4u76D3opS055929219760.2%
 
rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk55929216760.1%
 
rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ960615300.1%
 
rogid:16yTg05haoflKGNZTW4EqC7FSs055929211870.1%
 
rogid:HatR8w8+mNjtjr7s5+bAwaStpmk960611570.1%
 
rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk5592929400.1%
 
rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg96069310.1%
 
Other values (83514)107186895.8%
 
2020-11-13T20:46:13.170828image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique23663 ?
Unique (%)2.1%
2020-11-13T20:46:13.300918image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length214
Median length37
Mean length36.41036827
Min length1

Interaction Checksum(s)
Categorical

HIGH CARDINALITY

Distinct503579
Distinct (%)45.0%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
 
41874
rigid:Fo+Wm15MY+EIxDwf1RBEBTU7yoM
 
3606
intact-crc:DEFA161B30DBD5DF
 
1561
rigid:JVcpCLas8d6I6fGK1Q/+ypqrw0o
 
1423
intact-crc:A16CFA73CF6AE082
 
1349
Other values (503574)
1069082 
ValueCountFrequency (%) 
-418743.7%
 
rigid:Fo+Wm15MY+EIxDwf1RBEBTU7yoM36060.3%
 
intact-crc:DEFA161B30DBD5DF15610.1%
 
rigid:JVcpCLas8d6I6fGK1Q/+ypqrw0o14230.1%
 
intact-crc:A16CFA73CF6AE08213490.1%
 
rigid:hUbL2fgW3cjMC0bCi1Q5XasXrYA12960.1%
 
intact-crc:E0A1E677EE94106812480.1%
 
intact-crc:9169064DE4E40F94|rigid:kxxLRAU3XBe6AHV6qGD2WMF/KiA12150.1%
 
intact-crc:8068965A3E0EFBAC10880.1%
 
intact-crc:11F865E5D980376010850.1%
 
Other values (503569)106315095.0%
 
2020-11-13T20:46:15.253750image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique386568 ?
Unique (%)34.5%
2020-11-13T20:46:15.478128image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length61
Median length33
Mean length43.96408689
Min length1

Negative
Boolean

CONSTANT
REJECTED

Distinct1
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size1.1 MiB
False
1118895 
ValueCountFrequency (%) 
False1118895100.0%
 
2020-11-13T20:46:15.547961image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Feature(s) interactor A
Categorical

HIGH CARDINALITY

Distinct72669
Distinct (%)6.5%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
488993 
tandem tag:c-c
101358 
gal4 activation domain:n-n
62900 
gal4 activation domain:c-c
 
32366
tandem tag:n-n
 
32163
Other values (72664)
401115 
ValueCountFrequency (%) 
-48899343.7%
 
tandem tag:c-c1013589.1%
 
gal4 activation domain:n-n629005.6%
 
gal4 activation domain:c-c323662.9%
 
tandem tag:n-n321632.9%
 
calmodulin binding peptide plus protein a tag:c-c271432.4%
 
flag tag:c-c201231.8%
 
tandem tag:?-?181301.6%
 
tag:?-?166111.5%
 
flag tag:n-n146191.3%
 
Other values (72659)30448927.2%
 
2020-11-13T20:46:15.780836image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique61292 ?
Unique (%)5.5%
2020-11-13T20:46:15.925453image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length4638
Median length11
Mean length16.13789855
Min length1

Feature(s) interactor B
Categorical

HIGH CARDINALITY

Distinct68846
Distinct (%)6.2%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
814233 
gal4 dna binding domain:n-n
92918 
cub:?-?
 
12435
tandem tag:?-?
 
10599
tandem tag:c-c
 
4887
Other values (68841)
183823 
ValueCountFrequency (%) 
-81423372.8%
 
gal4 dna binding domain:n-n929188.3%
 
cub:?-?124351.1%
 
tandem tag:?-?105990.9%
 
tandem tag:c-c48870.4%
 
gal4 activation domain:n-n41640.4%
 
binding-associated region:?-?38920.3%
 
flag tag:?-?25360.2%
 
gal4 activation domain:c-c22930.2%
 
ha tag:?-?20880.2%
 
Other values (68836)16885015.1%
 
2020-11-13T20:46:16.211740image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique59573 ?
Unique (%)5.3%
2020-11-13T20:46:16.369311image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length48415
Median length1
Mean length10.88442883
Min length1
Distinct31
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
1070875 
1
 
43992
2
 
2461
4
 
564
3
 
389
Other values (26)
 
614
ValueCountFrequency (%) 
-107087595.7%
 
1439923.9%
 
224610.2%
 
45640.1%
 
3389< 0.1%
 
6214< 0.1%
 
5170< 0.1%
 
852< 0.1%
 
1037< 0.1%
 
732< 0.1%
 
Other values (21)109< 0.1%
 
2020-11-13T20:46:16.507935image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique11 ?
Unique (%)< 0.1%
2020-11-13T20:46:16.632905image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length3
Median length1
Mean length1.000128698
Min length1
Distinct27
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
-
1066058 
1
 
44086
0
 
6872
2
 
1190
3
 
194
Other values (22)
 
495
ValueCountFrequency (%) 
-106605895.3%
 
1440863.9%
 
068720.6%
 
211900.1%
 
3194< 0.1%
 
4175< 0.1%
 
5138< 0.1%
 
677< 0.1%
 
1224< 0.1%
 
716< 0.1%
 
Other values (17)65< 0.1%
 
2020-11-13T20:46:16.758571image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique6 ?
Unique (%)< 0.1%
2020-11-13T20:46:16.880245image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length3
Median length1
Mean length1.000073287
Min length1

Identification method participant A
Categorical

HIGH CARDINALITY

Distinct107
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0078"(nucleotide sequence identification)
344829 
psi-mi:"MI:0102"(sequence tag identification)
270172 
psi-mi:"MI:0396"(predetermined participant)
209412 
psi-mi:"MI:0427"(Identification by mass spectrometry)
82444 
psi-mi:"MI:0082"(peptide massfingerprinting)
51815 
Other values (102)
160223 
ValueCountFrequency (%) 
psi-mi:"MI:0078"(nucleotide sequence identification)34482930.8%
 
psi-mi:"MI:0102"(sequence tag identification)27017224.1%
 
psi-mi:"MI:0396"(predetermined participant)20941218.7%
 
psi-mi:"MI:0427"(Identification by mass spectrometry)824447.4%
 
psi-mi:"MI:0082"(peptide massfingerprinting)518154.6%
 
psi-mi:"MI:0113"(western blot)449534.0%
 
psi-mi:"MI:0705"(anti tag western blot)185621.7%
 
psi-mi:"MI:0658"(multidimensional protein identification technology)137841.2%
 
psi-mi:"MI:1180"(partial DNA sequence identification)128451.1%
 
psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)122681.1%
 
Other values (97)578115.2%
 
2020-11-13T20:46:17.019871image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique18 ?
Unique (%)< 0.1%
2020-11-13T20:46:17.172903image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length175
Median length45
Mean length47.51671068
Min length27

Identification method participant B
Categorical

HIGH CARDINALITY

Distinct115
Distinct (%)< 0.1%
Missing0
Missing (%)0.0%
Memory size8.5 MiB
psi-mi:"MI:0078"(nucleotide sequence identification)
344123 
psi-mi:"MI:0102"(sequence tag identification)
271349 
psi-mi:"MI:0396"(predetermined participant)
202910 
psi-mi:"MI:0427"(Identification by mass spectrometry)
90640 
psi-mi:"MI:0082"(peptide massfingerprinting)
51947 
Other values (110)
157926 
ValueCountFrequency (%) 
psi-mi:"MI:0078"(nucleotide sequence identification)34412330.8%
 
psi-mi:"MI:0102"(sequence tag identification)27134924.3%
 
psi-mi:"MI:0396"(predetermined participant)20291018.1%
 
psi-mi:"MI:0427"(Identification by mass spectrometry)906408.1%
 
psi-mi:"MI:0082"(peptide massfingerprinting)519474.6%
 
psi-mi:"MI:0113"(western blot)446094.0%
 
psi-mi:"MI:0705"(anti tag western blot)176891.6%
 
psi-mi:"MI:0658"(multidimensional protein identification technology)138571.2%
 
psi-mi:"MI:1180"(partial DNA sequence identification)128451.1%
 
psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)122791.1%
 
Other values (105)566475.1%
 
2020-11-13T20:46:17.327574image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Frequencies of value counts

Unique

Unique22 ?
Unique (%)< 0.1%
2020-11-13T20:46:17.481202image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
Histogram of lengths of the category

Length

Max length175
Median length45
Mean length47.5568333
Min length1

Correlations

2020-11-13T20:46:17.609502image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Pearson's r

The Pearson's correlation coefficient (r) is a measure of linear correlation between two variables. It's value lies between -1 and +1, -1 indicating total negative linear correlation, 0 indicating no linear correlation and 1 indicating total positive linear correlation. Furthermore, r is invariant under separate changes in location and scale of the two variables, implying that for a linear function the angle to the x-axis does not affect r.

To calculate r for two variables X and Y, one divides the covariance of X and Y by the product of their standard deviations.
2020-11-13T20:46:17.758608image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Spearman's ρ

The Spearman's rank correlation coefficient (ρ) is a measure of monotonic correlation between two variables, and is therefore better in catching nonlinear monotonic correlations than Pearson's r. It's value lies between -1 and +1, -1 indicating total negative monotonic correlation, 0 indicating no monotonic correlation and 1 indicating total positive monotonic correlation.

To calculate ρ for two variables X and Y, one divides the covariance of the rank variables of X and Y by the product of their standard deviations.
2020-11-13T20:46:18.013925image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Kendall's τ

Similarly to Spearman's rank correlation coefficient, the Kendall rank correlation coefficient (τ) measures ordinal association between two variables. It's value lies between -1 and +1, -1 indicating total negative correlation, 0 indicating no correlation and 1 indicating total positive correlation.

To calculate τ for two variables X and Y, one determines the number of concordant and discordant pairs of observations. τ is given by the number of concordant pairs minus the discordant pairs divided by the total number of pairs.
2020-11-13T20:46:18.162072image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Phik (φk)

Phik (φk) is a new and practical correlation coefficient that works consistently between categorical, ordinal and interval variables, captures non-linear dependency and reverts to the Pearson correlation coefficient in case of a bivariate normal input distribution. There is extensive documentation available here.
2020-11-13T20:46:18.403304image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Cramér's V (φc)

Cramér's V is an association measure for nominal random variables. The coefficient ranges from 0 to 1, with 0 indicating independence and 1 indicating perfect association. The empirical estimators used for Cramér's V have been proved to be biased, even for large samples. We use a bias-corrected measure that has been proposed by Bergsma in 2013 that can be found here.

Missing values

2020-11-13T20:43:13.642169image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/
2020-11-13T20:43:19.597136image/svg+xmlMatplotlib v3.3.2, https://matplotlib.org/

Sample

First rows

#ID(s) interactor AID(s) interactor BAlt. ID(s) interactor AAlt. ID(s) interactor BAlias(es) interactor AAlias(es) interactor BInteraction detection method(s)Publication 1st author(s)Publication Identifier(s)Taxid interactor ATaxid interactor BInteraction type(s)Source database(s)Interaction identifier(s)Confidence value(s)Expansion method(s)Biological role(s) interactor ABiological role(s) interactor BExperimental role(s) interactor AExperimental role(s) interactor BType(s) interactor AType(s) interactor BXref(s) interactor AXref(s) interactor BInteraction Xref(s)Annotation(s) interactor AAnnotation(s) interactor BInteraction annotation(s)Host organism(s)Interaction parameter(s)Creation dateUpdate dateChecksum(s) interactor AChecksum(s) interactor BInteraction Checksum(s)NegativeFeature(s) interactor AFeature(s) interactor BStoichiometry(s) interactor AStoichiometry(s) interactor BIdentification method participant AIdentification method participant B
0uniprotkb:P49418uniprotkb:O43426intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:EBI-2821539|uniprotkb:O43425|uniprotkb:O94984|uniprotkb:Q4KMR1psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:synj1_human(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121552|mint:MINT-16056intact-miscore:0.56-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-376294(identity)go:"GO:0007612"(learning)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43426|interpro:IPR034971|interpro:IPR034972|go:"GO:0007420"(brain development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0012506"(vesicle membrane)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0097060"(synaptic membrane)|reactome:R-HSA-8856828|refseq:XP_016883989.1|reactome:R-HSA-1660499|reactome:R-HSA-1855183|reactome:R-HSA-1855204|ensembl:ENSP00000349903|go:"GO:0098793"(presynapse)|go:"GO:0061024"(membrane organization)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030117"(membrane coat)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0048489"(synaptic vesicle transport)|ensembl:ENST00000357345|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0003723"(RNA binding)|refseq:NP_001153774.1|refseq:NP_001153778.1|refseq:NP_003886.3|refseq:NP_982271.2|ensembl:ENSG00000159082|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:1W80|rcsb pdb:2DNR|rcsb pdb:2VJ0|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR035979|interpro:IPR036691|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|mint:MINT-376287(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms|comment:"Stoichiometry: 1.0"comment:"Stoichiometry: 1.0"comment:homomint|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606intact-crc:F4234557A3B54840|rigid:n+UcEH4PPLkFnIyvBiXrLefK/xUFalsebinding-associated region:626-695(MINT-376295)binding-associated region:1063-1070(MINT-376288)--psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0078"(nucleotide sequence identification)
1uniprotkb:P49418intact:EBI-7121639intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:MINT-8094608psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:vrparrvlw(display_short)|psi-mi:EBI-7121639(display_long)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121634|mint:MINT-8094596intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0327"(peptide)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094601(identity)mint:MINT-8094610(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmscomment:mint|no-uniprot-update:figure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:lPy6gBhpgvyGSYgOqeHbjcqBtMQ-2intact-crc:880913D9000BF26E|rigid:iRObbQsaUeX0PxuKeQwZ73s8iKUFalsebinding-associated region:626-695(MINT-8094602)---psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0083"(peptide synthesis)
2uniprotkb:P49418intact:EBI-7121654intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:MINT-8094645psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:hrpvrraap(display_short)|psi-mi:EBI-7121654(display_long)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121659|mint:MINT-8094627intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0327"(peptide)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094629(identity)mint:MINT-8094647(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmscomment:mint|no-uniprot-update:figure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:GsDnsVmAo8ZZoKTZ4/uDb2x+h3c-2intact-crc:B68245E1F0508124|rigid:SlinPP5vIczFOGZjelrO+IXJq1sFalsebinding-associated region:626-695(MINT-8094630)---psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0083"(peptide synthesis)
3uniprotkb:P49418intact:EBI-7121715intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:MINT-8094663psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:vrptraada(display_short)|psi-mi:EBI-7121715(display_long)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121710|mint:MINT-8094651intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0327"(peptide)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094653(identity)mint:MINT-8094665(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmscomment:mint|no-uniprot-update:figure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:M+f6GE3SQXrMBiIVttW1MKhz3M0-2intact-crc:8F7F46DF027DF34E|rigid:uiWbDe6gaj1XcnJXNxuLLq2l/m4Falsebinding-associated region:626-695(MINT-8094654)---psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0083"(peptide synthesis)
4intact:EBI-7121765uniprotkb:P49418intact:MINT-8094691intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0psi-mi:xrprrghal(display_short)|psi-mi:EBI-7121765(display_long)psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121760|mint:MINT-8094677intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0327"(peptide)psi-mi:"MI:0326"(protein)mint:MINT-8094693(identity)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094679(identity)-comment:mint|no-uniprot-update:function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmsfigure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:cilZXZ3YLDI1s7n8WNRyUE6EnJQ-2rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606intact-crc:2EF43A66D9B2D428|rigid:/ki1zA46M4Q+rHcjCcxNhhk+5XwFalse-binding-associated region:626-695(MINT-8094680)--psi-mi:"MI:0083"(peptide synthesis)psi-mi:"MI:0078"(nucleotide sequence identification)
5uniprotkb:P49418intact:EBI-7121785intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:MINT-8094718psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:hrptrskla(display_short)|psi-mi:EBI-7121785(display_long)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121780|mint:MINT-8094706intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0327"(peptide)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094708(identity)mint:MINT-8094720(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmscomment:mint|no-uniprot-update:figure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:Q9S7HY0OYKNz5U6ndWhu91PBN5Q-2intact-crc:84BF0FF8155AE7F8|rigid:XLOVWM25uJw3qiUhKe6tGNH97NEFalsebinding-associated region:626-695(MINT-8094709)---psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0083"(peptide synthesis)
6intact:EBI-7121821uniprotkb:P49418intact:MINT-8094732intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0psi-mi:krpprdgtl(display_short)|psi-mi:EBI-7121821(display_long)psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121816|mint:MINT-8094722intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0327"(peptide)psi-mi:"MI:0326"(protein)mint:MINT-8094734(identity)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094724(identity)-comment:mint|no-uniprot-update:function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmsfigure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:EBbNcr0zagot59cukEv+Me2oOy4-2rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606intact-crc:830DCFFA177D7718|rigid:JRSHO660pb1Xran2F9HWsNTty4EFalse-binding-associated region:626-695(MINT-8094725)--psi-mi:"MI:0083"(peptide synthesis)psi-mi:"MI:0078"(nucleotide sequence identification)
7uniprotkb:P49418intact:EBI-7121875intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0intact:MINT-8094747psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:qrplrrprm(display_short)|psi-mi:EBI-7121875(display_long)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:9606(human)|taxid:9606(Homo sapiens)taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121870|mint:MINT-8094737intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0498"(prey)psi-mi:"MI:0496"(bait)psi-mi:"MI:0326"(protein)psi-mi:"MI:0327"(peptide)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094739(identity)mint:MINT-8094749(identity)-function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmscomment:mint|no-uniprot-update:figure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606rogid:+PG7mBSIIqI0Qjrscg1Dca7xq4E-2intact-crc:EBBB881A8816BA19|rigid:WzBj7stdRfHpLxVuhfndNR9eoncFalsebinding-associated region:626-695(MINT-8094740)---psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0083"(peptide synthesis)
8intact:EBI-7121931uniprotkb:P49418intact:MINT-8094812intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0psi-mi:rrprrslpe(display_short)|psi-mi:EBI-7121931(display_long)psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121926|mint:MINT-8094793intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0327"(peptide)psi-mi:"MI:0326"(protein)mint:MINT-8094814(identity)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094795(identity)-comment:mint|no-uniprot-update:function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmsfigure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:mzrTgOnke4NRW+G9BPdWpU6Lhec-2rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606intact-crc:DC0C4486AEA6B83F|rigid:GTdqKccRaAT8WnHgZCAJQsSmYsEFalse-binding-associated region:626-695(MINT-8094796)--psi-mi:"MI:0083"(peptide synthesis)psi-mi:"MI:0078"(nucleotide sequence identification)
9intact:EBI-7121906uniprotkb:P49418intact:MINT-8094788intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0psi-mi:tpkrppril(display_short)|psi-mi:EBI-7121906(display_long)psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)psi-mi:"MI:0084"(phage display)Cestra et al. (1999)pubmed:10542231|mint:MINT-5211933taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0471"(MINT)intact:EBI-7121911|mint:MINT-8094755intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0327"(peptide)psi-mi:"MI:0326"(protein)mint:MINT-8094790(identity)rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094757(identity)-comment:mint|no-uniprot-update:function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasmsfigure legend:F1 F2|comment:domino|comment:minttaxid:-1(in vitro)|taxid:-1(In vitro)-2001/01/102014/10/16rogid:Sbd4rq4/EaxV04gaweZHEWSw2hI-2rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606intact-crc:D4B9F42A78EEEAD3|rigid:FkC6ZpD/4st+D9Zvy2EdtJeUXxAFalse-binding-associated region:626-695(MINT-8094758)--psi-mi:"MI:0083"(peptide synthesis)psi-mi:"MI:0078"(nucleotide sequence identification)

Last rows

#ID(s) interactor AID(s) interactor BAlt. ID(s) interactor AAlt. ID(s) interactor BAlias(es) interactor AAlias(es) interactor BInteraction detection method(s)Publication 1st author(s)Publication Identifier(s)Taxid interactor ATaxid interactor BInteraction type(s)Source database(s)Interaction identifier(s)Confidence value(s)Expansion method(s)Biological role(s) interactor ABiological role(s) interactor BExperimental role(s) interactor AExperimental role(s) interactor BType(s) interactor AType(s) interactor BXref(s) interactor AXref(s) interactor BInteraction Xref(s)Annotation(s) interactor AAnnotation(s) interactor BInteraction annotation(s)Host organism(s)Interaction parameter(s)Creation dateUpdate dateChecksum(s) interactor AChecksum(s) interactor BInteraction Checksum(s)NegativeFeature(s) interactor AFeature(s) interactor BStoichiometry(s) interactor AStoichiometry(s) interactor BIdentification method participant AIdentification method participant B
1118885uniprotkb:P04849-PRO_0000039379uniprotkb:P04849-PRO_0000039380intact:EBI-26302374intact:EBI-26302379psi-mi:pro_0000039379(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)psi-mi:pro_0000039380(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short)psi-mi:"MI:0114"(x-ray crystallography)Welch et al. (2012)imex:IM-28357|pubmed:23012473taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)")taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)")psi-mi:"MI:0915"(physical association)psi-mi:"MI:0465"(DIP)intact:EBI-26302357|wwpdb:4GIP|imex:IM-28357-1intact-miscore:0.40-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)intact:EBI-26302359(chain-parent)uniprotkb:P04849(chain-parent)---figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/17rogid:j18699Ed29miQ2sSyoGew4jGL8U11208rogid:Zfmx6vvpdcvCVtuntaSGZ4uWUZI11208rigid:Usx80fpK2Qb32CmxT4Ppm+reFCQFalsebinding-associated region:1-81binding-associated region:1-377|his tag:c-c|tag:c-c33psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118886uniprotkb:P15170uniprotkb:P62495intact:EBI-948993|uniprotkb:Q96GF2|uniprotkb:J3KQG6intact:EBI-750990|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|intact:EBI-1047744psi-mi:erf3a_human(display_long)|uniprotkb:ERF3A(gene name synonym)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)psi-mi:erf1_human(display_long)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short)psi-mi:"MI:0410"(3D electron microscopy)Taylor et al. (2012)imex:IM-28363|pubmed:23091004taxid:9606(human)|taxid:9606(Homo sapiens)taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26302415|wwpdb:3J5Y|emdb:EMD-5801|imex:IM-28363-1intact-miscore:0.64-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:3J5Y|rcsb pdb:5LZT|ensembl:ENST00000420576|ensembl:ENST00000434724|ensembl:ENST00000439887|ensembl:ENST00000563468|ensembl:ENSP00000398131|ensembl:ENSP00000399539|ensembl:ENSP00000408399|ensembl:ENSP00000454351|rcsb pdb:4D61|go:"GO:0006449"(regulation of translational termination)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0005829"(cytosol)|go:"GO:0018444"(translation release factor complex)|mint:P15170|go:"GO:0003723"(RNA binding)|interpro:IPR031157|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003747"(translation release factor activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0006479"(protein methylation)|refseq:NP_001123479.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|rcsb pdb:3E1Y|ensembl:ENSG00000103342|refseq:NP_001123478.1|go:"GO:0006412"(translation)|reactome:R-HSA-9010553|rcsb pdb:3KUI|interpro:IPR027417|rcsb pdb:5HXB|reactome:R-HSA-72764|reactome:R-HSA-975956|reactome:R-HSA-975957go:"GO:0005737"(cytoplasm)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR024049|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:3E1Y|rcsb pdb:3J5Y|ensembl:ENSP00000353741|ensembl:ENST00000360541|refseq:NP_004721.1|refseq:NP_001243231.1|reactome:R-HSA-9010553|rcsb pdb:5LZT|rcsb pdb:5LZU|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|interpro:IPR029064|ensembl:ENST00000499810|rcsb pdb:5LZV|ensembl:ENSG00000120705|ensembl:ENSP00000421288|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|mint:P62495|interpro:IPR042226|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|go:"GO:1990825"(sequence-specific mRNA binding)|rcsb pdb:6D90|rcsb pdb:2MQ6|rcsb pdb:2MQ9|reactome:R-HSA-72764|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0043022"(ribosome binding)|rcsb pdb:1DT9|rcsb pdb:2HST|go:"GO:0006415"(translational termination)|go:"GO:0018444"(translation release factor complex)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0002184"(cytoplasmic translational termination)|rcsb pdb:6IP8---figure legend:Fig 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/17rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606rigid:otY7vxMHvTdCYV3mXIPgpNcSeXkFalsebinding-associated region:69-496binding-associated region:7-42011psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
1118887uniprotkb:I0CES9uniprotkb:B4YNG0intact:EBI-26302445intact:EBI-26302437psi-mi:i0ces9_9viru(display_long)|uniprotkb:Sputnik3_R18(orf name)psi-mi:capsd_sptnk(display_long)|uniprotkb:ORF20(orf name)psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)Zhang et al. (2012)pubmed:23091035|imex:IM-28358taxid:1133032(Sputnik virophage 3)|taxid:1133032(Sputnik virophage 3)taxid:543939(Sputnik virophage)|taxid:543939(Sputnik virophage)psi-mi:"MI:0915"(physical association)psi-mi:"MI:0465"(DIP)intact:EBI-26302434|wwpdb:3J26|emdb:EMD-5495|imex:IM-28358-1intact-miscore:0.32-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:3J26refseq:YP_002122381.1|rcsb pdb:3J26|go:"GO:0019028"(viral capsid)---figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:5757(acapo)|taxid:5757(Acanthamoeba polyphaga)-2020/09/172020/09/17rogid:XVToqQ/VXteviqtNBOjE2DbSfv81133032rogid:MUM/YhbIoTQLrDSJ+EQyV8zDg4Y543939rigid:5hhqM5aMLCkjojsVhWzG03L/iEcFalse-binding-associated region:1-508113psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
1118888uniprotkb:Q12285uniprotkb:Q12285intact:EBI-34904|uniprotkb:D6W1V6intact:EBI-34904|uniprotkb:D6W1V6psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)psi-mi:"MI:0114"(x-ray crystallography)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26302650|wwpdb:4A20|imex:IM-28359-1intact-miscore:0.44-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKUgo:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU-crc64:CE6FC4282E0E472Ccrc64:CE6FC4282E0E472Cfigure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")-2020/09/172020/09/17rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292rigid:p95S+N5uZkDbF8FS2Q2uWnHS+yQFalsebinding-associated region:70-152(IPR000626)|his tag:n-nbinding-associated region:70-152(IPR000626)|his tag:n-n20psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118889uniprotkb:Q12118uniprotkb:Q12118intact:EBI-31784|uniprotkb:D6W273intact:EBI-31784|uniprotkb:D6W273psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:1103"(solution state nmr)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26302663|wwpdb:4ASV|imex:IM-28359-3intact-miscore:0.59-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:33539B74F742BD3Ccrc64:33539B74F742BD3Cfigure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/17rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:Ab6ImX1QHM8e04eb1/cY6/oIgqAFalsehis tag:n-n|binding-associated region:1-78his tag:n-n|binding-associated region:1-7820psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118890uniprotkb:Q12285uniprotkb:Q12118intact:EBI-34904|uniprotkb:D6W1V6intact:EBI-31784|uniprotkb:D6W273psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:1103"(solution state nmr)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26302669|wwpdb:4ASW|imex:IM-28359-5intact-miscore:0.95-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKUgo:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:CE6FC4282E0E472Ccrc64:33539B74F742BD3Cfigure legend:Figure S1A|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/21rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3YFalsebinding-associated region:70-152(IPR000626)binding-associated region:1-78|15n label:?-?12psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118891uniprotkb:Q12118uniprotkb:Q12118intact:EBI-31784|uniprotkb:D6W273intact:EBI-31784|uniprotkb:D6W273psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:1103"(solution state nmr)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26355058|imex:IM-28359-9intact-miscore:0.59-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:33539B74F742BD3Ccrc64:33539B74F742BD3Cfigure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/21rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:mmtD4irrtiIV6dsz3UoDRum1HlUFalsehis tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?his tag:n-n|binding-associated region:1-7811psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118892uniprotkb:Q12118uniprotkb:Q12118intact:EBI-31784|uniprotkb:D6W273intact:EBI-31784|uniprotkb:D6W273psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:1103"(solution state nmr)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26355075|imex:IM-28359-11intact-miscore:0.59-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:33539B74F742BD3Ccrc64:33539B74F742BD3Cfigure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/21rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:mmtD4irrtiIV6dsz3UoDRum1HlUFalsehis tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-?11psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118893uniprotkb:Q12285uniprotkb:Q12118intact:EBI-34904|uniprotkb:D6W1V6intact:EBI-31784|uniprotkb:D6W273psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:1103"(solution state nmr)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26355105|imex:IM-28359-13intact-miscore:0.95-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKUgo:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:CE6FC4282E0E472Ccrc64:33539B74F742BD3Cfigure legend:Figure S1B|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2020/09/172020/09/21rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3YFalsebinding-associated region:70-152(IPR000626)|15n label:?-?binding-associated region:1-7812psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)
1118894uniprotkb:Q12285uniprotkb:Q12118intact:EBI-34904|uniprotkb:D6W1V6intact:EBI-31784|uniprotkb:D6W273psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym)psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name)psi-mi:"MI:0065"(isothermal titration calorimetry)Simon et al. (2013)pubmed:23297211|imex:IM-28359taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)psi-mi:"MI:0407"(direct interaction)psi-mi:"MI:0465"(DIP)intact:EBI-26302723|imex:IM-28359-7intact-miscore:0.95-psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKUgo:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734-crc64:CE6FC4282E0E472Ccrc64:33539B74F742BD3Cfigure legend:Fig 2, Table S3|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)kd:0.11x10^-6(molar)2020/09/172020/09/21rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3YFalsebinding-associated region:70-152(IPR000626)binding-associated region:1-78|mutation disrupting interaction strength:38-38|mutation with no effect:16-16|mutation decreasing interaction strength:31-31|mutation decreasing interaction strength:35-35|mutation decreasing interaction strength:42-4212psi-mi:"MI:0396"(predetermined participant)psi-mi:"MI:0396"(predetermined participant)

Duplicate rows

Most frequent

#ID(s) interactor AID(s) interactor BAlt. ID(s) interactor AAlt. ID(s) interactor BAlias(es) interactor AAlias(es) interactor BInteraction detection method(s)Publication 1st author(s)Publication Identifier(s)Taxid interactor ATaxid interactor BInteraction type(s)Source database(s)Interaction identifier(s)Confidence value(s)Expansion method(s)Biological role(s) interactor ABiological role(s) interactor BExperimental role(s) interactor AExperimental role(s) interactor BType(s) interactor AType(s) interactor BXref(s) interactor AXref(s) interactor BInteraction Xref(s)Annotation(s) interactor AAnnotation(s) interactor BInteraction annotation(s)Host organism(s)Interaction parameter(s)Creation dateUpdate dateChecksum(s) interactor AChecksum(s) interactor BInteraction Checksum(s)NegativeFeature(s) interactor AFeature(s) interactor BStoichiometry(s) interactor AStoichiometry(s) interactor BIdentification method participant AIdentification method participant Bcount
146uniprotkb:P04578uniprotkb:P01889intact:EBI-6163496|uniprotkb:O09779intact:EBI-1046513|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793psi-mi:env_hv1h2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym)psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)psi-mi:"MI:0007"(anti tag coimmunoprecipitation)Jager et al. (2012)imex:IM-17346|pubmed:22190034|psi-mi:"MI:0007"taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0914"(association)psi-mi:"MI:0469"(IntAct)intact:EBI-6174316|imex:IM-17346-4intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:5ZCX|rcsb pdb:5GHW|rcsb pdb:5H0N|rcsb pdb:5KA5|rcsb pdb:5KA6|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019068"(virion assembly)|go:"GO:0019082"(viral protein processing)|rcsb pdb:1MZI|go:"GO:0019058"(viral life cycle)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:2MG1|rcsb pdb:2MG2|rcsb pdb:2MG3|rcsb pdb:4YDV|rcsb pdb:4ZTO|rcsb pdb:5C0R|rcsb pdb:5C0S|rcsb pdb:3DRO|rcsb pdb:5IVX|rcsb pdb:5X08|dip:DIP-58525N|reactome:R-HSA-1462054|reactome:R-HSA-162588|reactome:R-HSA-171286|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-5621480|interpro:IPR037527|rcsb pdb:1FAV|rcsb pdb:3J70|rcsb pdb:5CMU|rcsb pdb:5CMZ|rcsb pdb:5CN0|go:"GO:0042802"(identical protein binding)|interpro:IPR036377|rcsb pdb:5DD0|rcsb pdb:5CIL|rcsb pdb:5CIN|rcsb pdb:3MNZ|rcsb pdb:5HM1|rcsb pdb:5NWU|rcsb pdb:5YB4|rcsb pdb:5Z0W|rcsb pdb:6BXQ|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019012"(virion)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|rcsb pdb:5BN0|mint:P04578|rcsb pdb:2NY7|rcsb pdb:6MQC|rcsb pdb:6MQE|rcsb pdb:6MQM|rcsb pdb:6MQR|rcsb pdb:6MQS|rcsb pdb:6N16|rcsb pdb:6NCP|rcsb pdb:6PSA|rcsb pdb:6SNC|rcsb pdb:6SND|rcsb pdb:6SNE|rcsb pdb:5TKJ|rcsb pdb:5TKK|rcsb pdb:5WDF|rcsb pdb:6BXP|rcsb pdb:6DLN|rcsb pdb:5NVP|rcsb pdb:5NWW|rcsb pdb:5YB2|rcsb pdb:5YB3|rcsb pdb:5YC0|rcsb pdb:6B9K|rcsb pdb:6DE7|rcsb pdb:3D0V|rcsb pdb:2ME1|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|rcsb pdb:1AIK|rcsb pdb:1DF4|rcsb pdb:1DF5|rcsb pdb:1DLB|rcsb pdb:1G9M|rcsb pdb:1GC1|rcsb pdb:1GZL|rcsb pdb:1K33|rcsb pdb:1K34|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:1RZJ|rcsb pdb:2CMR|rcsb pdb:2PV6|rcsb pdb:2XRA|rcsb pdb:3DNL|rcsb pdb:3DNN|rcsb pdb:3DNO|rcsb pdb:3IDX|rcsb pdb:3IDY|rcsb pdb:3TYG|rcsb pdb:3VIE|refseq:NP_057856.1|rcsb pdb:5HFL|rcsb pdb:4JPJ|rcsb pdb:4JPK|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)rcsb pdb:3VCL|rcsb pdb:4U1H|rcsb pdb:4U1K|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|ensembl:ENSG00000234745|ensembl:ENSP00000399168|ensembl:ENST00000412585|refseq:NP_005505.2|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0006952"(defense response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|mint:P01889|rcsb pdb:6MTL|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|rcsb pdb:6PYJpsi-mi:"MI:0007"(anti tag coimmunoprecipitation)comment:"DIP protein P04578 original sequence version: 85"|comment:"DIP protein P04578 original sequence version: 140"author-confidence:0.75figure legend:suppl. data 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)-2012/07/092019/11/11rogid:0cs6c9Wi6DV3vHjKBSlqRJ8keHk11706rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606intact-crc:213AE67A87EADC94|rigid:58CQMT8iUJmei4cC87auYqYHfbEFalsemutation:53-53,94-94,192-192,215-215,224-224,346-346,470-470,580-580("MI:0118")|tandem tag:c-c("MI:0677")---psi-mi:"MI:0102"(sequence tag identification)psi-mi:"MI:0102"(sequence tag identification)10
145uniprotkb:P03421intact:EBI-11473246intact:EBI-6930954|uniprotkb:P90196intact:EBI-11473188|intact:EBI-11473232|intact:EBI-11473238|intact:EBI-11473244|intact:EBI-11473268|intact:EBI-11473270|intact:EBI-11473290|intact:EBI-11473258|intact:EBI-11473282|intact:EBI-11473294psi-mi:phosp_hrsva(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short)psi-mi:h2a2a_mesau_protein(display_short)|psi-mi:EBI-11473246(display_long)psi-mi:"MI:0007"(anti tag coimmunoprecipitation)Munday et al. (2015)pubmed:25355874|imex:IM-25896taxid:11259(hrsva)|taxid:11259(human respiratory sy)taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")psi-mi:"MI:0914"(association)psi-mi:"MI:1335"(HPIDb)intact:EBI-11364790|imex:IM-25896-3intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:6PZK|interpro:IPR003487(Phosphoprotein, pneumoviral)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0019012"(virion)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:4UCB|rcsb pdb:6G0Y---comment:similar to Q6GSS7 H2A2A_MOUSE|comment:similar to P17932 RL32P_MOUSE|comment:similar to Q9Z130 HNRDL_MOUSE|comment:similar to P06151 LDHA_MOUSE|comment:similar to P62984 RL40_MOUSE|comment:similar to P62918 RL8_MOUSE|comment:similar to P62900 RL31_MOUSEfigure legend:S2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21)-2015/10/292019/02/21rogid:JX7IyIOgX+Hy/wIRNw4pGOQrXzs11259--Falseenhanced green fluorescent protein tag:32-32---psi-mi:"MI:0102"(sequence tag identification)psi-mi:"MI:0102"(sequence tag identification)9
202uniprotkb:P28887intact:EBI-11473246intact:EBI-11364737|uniprotkb:O41356|uniprotkb:O41355|uniprotkb:P90197|uniprotkb:Q82021intact:EBI-11473188|intact:EBI-11473232|intact:EBI-11473238|intact:EBI-11473244|intact:EBI-11473268|intact:EBI-11473270|intact:EBI-11473290|intact:EBI-11473258|intact:EBI-11473282|intact:EBI-11473294psi-mi:l_hrsva(display_long)|uniprotkb:L(gene name)|psi-mi:L(display_short)|uniprotkb:Large structural protein(gene name synonym)|uniprotkb:Replicase(gene name synonym)|uniprotkb:Transcriptase(gene name synonym)psi-mi:h2a2a_mesau_protein(display_short)|psi-mi:EBI-11473246(display_long)psi-mi:"MI:0007"(anti tag coimmunoprecipitation)Munday et al. (2015)pubmed:25355874|imex:IM-25896taxid:11259(hrsva)|taxid:11259(human respiratory sy)taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")psi-mi:"MI:0914"(association)psi-mi:"MI:1335"(HPIDb)intact:EBI-11364735|imex:IM-25896-1intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)interpro:IPR016269(RNA-directed RNA polymerase, paramyxovirus)|go:"GO:0039689"(negative stranded viral RNA replication)|interpro:IPR039736|rcsb pdb:6PZK|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0019012"(virion)|go:"GO:0005524"(ATP binding)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR014023(RNA-directed RNA polymerase catalytic)|interpro:IPR025786|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|interpro:IPR026890---comment:similar to Q6GSS7 H2A2A_MOUSE|comment:similar to P17932 RL32P_MOUSE|comment:similar to Q9Z130 HNRDL_MOUSE|comment:similar to P06151 LDHA_MOUSE|comment:similar to P62984 RL40_MOUSE|comment:similar to P62918 RL8_MOUSE|comment:similar to P62900 RL31_MOUSEfigure legend:S1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21)-2015/10/292019/02/21rogid:SzpLo1VW6p3PDK0g+ErGsMEA+BU11259--Falseenhanced green fluorescent protein tag:1738-1739---psi-mi:"MI:0102"(sequence tag identification)psi-mi:"MI:0102"(sequence tag identification)5
46uniprotkb:A0A1L8G4G8uniprotkb:B1WBE0intact:EBI-3645294intact:EBI-3510530psi-mi:a0a1l8g4g8_xenla(display_long)|uniprotkb:hdlbp.S(gene name)|psi-mi:hdlbp.S(display_short)|uniprotkb:XELAEV_18029889mg(orf name)psi-mi:b1wbe0_xenla(display_long)|uniprotkb:eprs1.S(gene name)|psi-mi:eprs1.S(display_short)|uniprotkb:LOC100158438(gene name synonym)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:eprs(gene name synonym)|uniprotkb:eprs1(gene name synonym)psi-mi:"MI:0029"(cosedimentation through density gradient)Gache et al. (2010)pubmed:20174651|imex:IM-17228taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")psi-mi:"MI:0403"(colocalization)psi-mi:"MI:0469"(IntAct)intact:EBI-3645151|imex:IM-17228-3intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)interpro:IPR036612|uniprotkb:Q7ZTN2(uniprot-removed-ac)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:XP_018121321.1|refseq:XP_018121322.1go:"GO:0005737"(cytoplasm)|go:"GO:0005524"(ATP binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|refseq:NP_001121346.1|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020061|interpro:IPR020058|interpro:IPR020059|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR000738(WHEP-TRS)|interpro:IPR033721|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR036282|interpro:IPR036621---figure legend:Table S1|caution:"The participant EBI-3645738() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis)-2011/02/142018/02/26rogid:bD8k16jeBUqq4mj5k0OvlJRS6EQ8355rogid:cX8k4MBg+cf51rz5jkJKvwZH5VM8355intact-crc:0F5278A54AD61E9DFalse----psi-mi:"MI:0082"(peptide massfingerprinting)psi-mi:"MI:0082"(peptide massfingerprinting)4
593uniprotkb:Q9WMX2-PRO_0000037545uniprotkb:P22736intact:EBI-9028517intact:EBI-721550|uniprotkb:Q15627|uniprotkb:Q53Y00|uniprotkb:Q6IBU8|uniprotkb:B4DML7psi-mi:q9wmx2-pro_0000037545(display_long)psi-mi:nr4a1_human(display_long)|uniprotkb:Nuclear hormone receptor NUR/77(gene name synonym)|uniprotkb:Testicular receptor 3(gene name synonym)|uniprotkb:Orphan nuclear receptor HMR(gene name synonym)|uniprotkb:Early response protein NAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR3(gene name synonym)|uniprotkb:ST-59(gene name synonym)|uniprotkb:GFRP1(gene name synonym)|uniprotkb:HMR(gene name synonym)|uniprotkb:NAK1(gene name synonym)|uniprotkb:NR4A1(gene name)|psi-mi:NR4A1(display_short)psi-mi:"MI:0018"(two hybrid)de et al. (2008)pubmed:18985028|imex:IM-25957taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0915"(physical association)psi-mi:"MI:1335"(HPIDb)intact:EBI-9078372|imex:IM-25957-623intact-miscore:0.37psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)intact:EBI-710918(chain-parent)rcsb pdb:4JGV|rcsb pdb:4KZI|rcsb pdb:4KZJ|rcsb pdb:4KZM|refseq:NP_002126.2|refseq:NP_775180.1|ensembl:ENSG00000123358|interpro:IPR003071(Orphan nuclear receptor, HMR type)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:2QW4|go:"GO:0042025"(host cell nucleus)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005829"(cytosol)|refseq:XP_005268881.1|go:"GO:0005634"(nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|reactome:R-HSA-198693|reactome:R-HSA-383280|reactome:R-HSA-5674400|refseq:XP_006719426.1|refseq:XP_006719427.1|ensembl:ENSP00000243050|ensembl:ENSP00000353427|ensembl:ENSP00000378301|ensembl:ENSP00000378302|ensembl:ENSP00000449539|ensembl:ENSP00000449587|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|rcsb pdb:4RE8|rcsb pdb:4REE|rcsb pdb:4REF|rcsb pdb:4WHF|rcsb pdb:4WHG|rcsb pdb:4RZE|rcsb pdb:4RZF|rcsb pdb:4RZG|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0000790"(nuclear chromatin)|go:"GO:0005739"(mitochondrion)|rcsb pdb:6LC1|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0035259"(glucocorticoid receptor binding)|interpro:IPR035500|mint:P22736|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|dip:DIP-40392N|refseq:NP_001189162.1|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000243050|ensembl:ENST00000360284|ensembl:ENST00000394824|ensembl:ENST00000394825|ensembl:ENST00000548232|ensembl:ENST00000550082|rcsb pdb:3V3E|rcsb pdb:3V3Q--comment:"DIP protein P22736 original sequence version: 156"figure legend:Supp data S1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)-2013/11/252017/09/02rogid:fOz8NHDQRviw5MpyTRtVblSks5c333284rogid:yocf+C94vprIeNXXB89p3tqzW/c9606intact-crc:43DDC491C360014F|rigid:W+BpLyAZ0FD2VlfvTvO9sa1haEMFalse----psi-mi:"MI:0078"(nucleotide sequence identification)psi-mi:"MI:0078"(nucleotide sequence identification)4
1chebi:"CHEBI:16618"uniprotkb:P01889intact:EBI-1257125intact:EBI-1046513|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793psi-mi:1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate(display_short)|psi-mi:"CHEBI:16618"(display_long)psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym)psi-mi:"MI:0096"(pull down)Catimel et al. (2009)pubmed:19463016|imex:IM-17246taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0914"(association)psi-mi:"MI:0469"(IntAct)intact:EBI-4289959|imex:IM-17246-2intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0328"(small molecule)psi-mi:"MI:0326"(protein)-rcsb pdb:3VCL|rcsb pdb:4U1H|rcsb pdb:4U1K|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|ensembl:ENSG00000234745|ensembl:ENSP00000399168|ensembl:ENST00000412585|refseq:NP_005505.2|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0006952"(defense response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|mint:P01889|rcsb pdb:6MTL|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|rcsb pdb:6PYJ---figure legend:Supplementary Table 1 and 2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:-1(in vitro)|taxid:-1(In vitro)-2011/06/162019/11/11-rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606intact-crc:DE189F805D31868CFalse----psi-mi:"MI:0427"(Identification by mass spectrometry)psi-mi:"MI:0427"(Identification by mass spectrometry)3
71uniprotkb:A5XAW2uniprotkb:Q8AWF5intact:EBI-3511040intact:EBI-1000337|uniprotkb:Q6NRM2psi-mi:a5xaw2_xenla(display_long)|uniprotkb:KHC(gene name)|psi-mi:KHC(display_short)psi-mi:ndc80_xenla(display_long)|uniprotkb:ndc80(gene name)|psi-mi:ndc80(display_short)|uniprotkb:kntc2(gene name synonym)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)psi-mi:"MI:0029"(cosedimentation through density gradient)Gache et al. (2010)pubmed:20174651|imex:IM-17228taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")psi-mi:"MI:0403"(colocalization)psi-mi:"MI:0469"(IntAct)intact:EBI-3511241|imex:IM-17228-2intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0497"(neutral component)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|go:"GO:0005874"(microtubule)|go:"GO:0005524"(ATP binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961interpro:IPR005550(HEC/Ndc80p)|go:"GO:0000777"(condensed chromosome kinetochore)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_001082372.1|interpro:IPR038273|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0000776"(kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR040967|refseq:XP_018103626.1---figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis)-2011/02/142019/01/23rogid:QglBQVdrfKZyyiGImgNFVONJ5D08355rogid:fbrLPmNbZRHqOGCcZZUpNZ0cJx48355intact-crc:F4752A99DA7D05A5False----psi-mi:"MI:0082"(peptide massfingerprinting)psi-mi:"MI:0082"(peptide massfingerprinting)3
90uniprotkb:O15372uniprotkb:O15372intact:EBI-709735intact:EBI-709735psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short)psi-mi:"MI:0007"(anti tag coimmunoprecipitation)Sowa et al. (2009)pubmed:19615732|imex:IM-12079taxid:9606(human)|taxid:9606(Homo sapiens)taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0915"(physical association)psi-mi:"MI:0469"(IntAct)intact:EBI-2510472|imex:IM-12079-55intact-miscore:0.40psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0016020"(membrane)|ensembl:ENST00000521861|mint:O15372|go:"GO:0003723"(RNA binding)|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000147677|ensembl:ENSP00000429931|dip:DIP-33689N|rcsb pdb:3J8B|rcsb pdb:3J8C|go:"GO:0070062"(extracellular exosome)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR037518|interpro:IPR027524|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_003747.1|interpro:IPR000555(Mov34/MPN/PAD-1)|go:"GO:0006413"(translational initiation)go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0016020"(membrane)|ensembl:ENST00000521861|mint:O15372|go:"GO:0003723"(RNA binding)|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000147677|ensembl:ENSP00000429931|dip:DIP-33689N|rcsb pdb:3J8B|rcsb pdb:3J8C|go:"GO:0070062"(extracellular exosome)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR037518|interpro:IPR027524|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_003747.1|interpro:IPR000555(Mov34/MPN/PAD-1)|go:"GO:0006413"(translational initiation)psi-mi:"MI:0469"(intact)comment:"DIP protein O15372 original sequence version: 74"|comment:"DIP protein O15372 original sequence version: 89"|comment:"DIP protein O15372 original sequence version: 118"comment:"DIP protein O15372 original sequence version: 74"|comment:"DIP protein O15372 original sequence version: 89"|comment:"DIP protein O15372 original sequence version: 118"figure legend:submitted by author|caution:"The participant EBI-366647(O75822) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510460(B0QY89) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366617(Q14152) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2509449() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353901(Q7L2H7) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347740(P60228) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-348169(P67870) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510446(P61221) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347451(P19784) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347804(P68400) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366632(O75821) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353741(Q99613) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-354047(Q13347) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2507547() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510474(Q5JT00) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510442(Q9BX72) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-354344(Q9UBQ5) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510439(O95065) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353818(O15371) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366696(P55884) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)-2009/12/182017/12/08rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606intact-crc:20F800B7B4841EDE|rigid:i3zuCcUqSmEYgzLsmrtzHSPk68MFalseha tag:n-n|flag tag:n-n---psi-mi:"MI:0102"(sequence tag identification)psi-mi:"MI:0102"(sequence tag identification)3
113uniprotkb:P00895uniprotkb:P37246intact:EBI-1118772|uniprotkb:P78249intact:EBI-1123174|uniprotkb:P77341|uniprotkb:Q2M630|uniprotkb:Q2MCF8psi-mi:trpe_ecoli(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:b1264(locus name)|uniprotkb:JW1256(locus name)psi-mi:insi_ecoli(display_long)|uniprotkb:insI1(gene name)|psi-mi:insI1(display_short)|uniprotkb:b0256(locus name)|uniprotkb:JW0246(locus name)|uniprotkb:insI2(gene name)|psi-mi:insI2(display_short)|uniprotkb:b1404(locus name)|uniprotkb:JW1401(locus name)|uniprotkb:insI3(gene name)|psi-mi:insI3(display_short)|uniprotkb:b4284(locus name)|uniprotkb:JW4244(locus name)psi-mi:"MI:0096"(pull down)Arifuzzaman et al. (2006)pubmed:16606699taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")psi-mi:"MI:0914"(association)psi-mi:"MI:0469"(IntAct)intact:EBI-1139361intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|refseq:WP_001194582.1|go:"GO:0004049"(anthranilate synthase activity)|go:"GO:0000162"(tryptophan biosynthetic process)|refseq:NP_415780.1|interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR005257(Anthranilate synthase component I, TrpE)refseq:AP_000909.1|refseq:AP_002030.1|refseq:AP_004775.1|refseq:NP_415922.1|refseq:NP_418704.1|go:"GO:0003677"(DNA binding)|go:"GO:0004803"(transposase activity)|go:"GO:0015074"(DNA integration)|go:"GO:0006313"(transposition, DNA-mediated)|refseq:YP_001294740.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001598(Transposase, IS30, conserved site)----taxid:316407(ecow3)|taxid:316407("Escherichia coli (strain K12 / W3110 / ATCC 27325 / DSM 5911)")-2006/10/242014/10/16rogid:OZ1/ZKSrXlVRyfE6EpNIE+aF0l483333rogid:3GKoT+3fbkbyHbtUS6vI82OVIXk83333intact-crc:4A6897CFD632EDDF|rigid:cYdXr/hTy/Xkidhh/+vh6KqSFM0Falsehis tag:?-?-11psi-mi:"MI:0427"(Identification by mass spectrometry)psi-mi:"MI:0427"(Identification by mass spectrometry)3
147uniprotkb:P04578uniprotkb:P10321intact:EBI-6163496|uniprotkb:O09779intact:EBI-1051396|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063psi-mi:env_hv1h2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym)psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)psi-mi:"MI:0007"(anti tag coimmunoprecipitation)Jager et al. (2012)imex:IM-17346|pubmed:22190034|psi-mi:"MI:0007"taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)")taxid:9606(human)|taxid:9606(Homo sapiens)psi-mi:"MI:0914"(association)psi-mi:"MI:0469"(IntAct)intact:EBI-6174316|imex:IM-17346-4intact-miscore:0.35psi-mi:"MI:1060"(spoke expansion)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0499"(unspecified role)psi-mi:"MI:0496"(bait)psi-mi:"MI:0498"(prey)psi-mi:"MI:0326"(protein)psi-mi:"MI:0326"(protein)rcsb pdb:5ZCX|rcsb pdb:5GHW|rcsb pdb:5H0N|rcsb pdb:5KA5|rcsb pdb:5KA6|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019068"(virion assembly)|go:"GO:0019082"(viral protein processing)|rcsb pdb:1MZI|go:"GO:0019058"(viral life cycle)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:2MG1|rcsb pdb:2MG2|rcsb pdb:2MG3|rcsb pdb:4YDV|rcsb pdb:4ZTO|rcsb pdb:5C0R|rcsb pdb:5C0S|rcsb pdb:3DRO|rcsb pdb:5IVX|rcsb pdb:5X08|dip:DIP-58525N|reactome:R-HSA-1462054|reactome:R-HSA-162588|reactome:R-HSA-171286|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-5621480|interpro:IPR037527|rcsb pdb:1FAV|rcsb pdb:3J70|rcsb pdb:5CMU|rcsb pdb:5CMZ|rcsb pdb:5CN0|go:"GO:0042802"(identical protein binding)|interpro:IPR036377|rcsb pdb:5DD0|rcsb pdb:5CIL|rcsb pdb:5CIN|rcsb pdb:3MNZ|rcsb pdb:5HM1|rcsb pdb:5NWU|rcsb pdb:5YB4|rcsb pdb:5Z0W|rcsb pdb:6BXQ|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019012"(virion)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|rcsb pdb:5BN0|mint:P04578|rcsb pdb:2NY7|rcsb pdb:6MQC|rcsb pdb:6MQE|rcsb pdb:6MQM|rcsb pdb:6MQR|rcsb pdb:6MQS|rcsb pdb:6N16|rcsb pdb:6NCP|rcsb pdb:6PSA|rcsb pdb:6SNC|rcsb pdb:6SND|rcsb pdb:6SNE|rcsb pdb:5TKJ|rcsb pdb:5TKK|rcsb pdb:5WDF|rcsb pdb:6BXP|rcsb pdb:6DLN|rcsb pdb:5NVP|rcsb pdb:5NWW|rcsb pdb:5YB2|rcsb pdb:5YB3|rcsb pdb:5YC0|rcsb pdb:6B9K|rcsb pdb:6DE7|rcsb pdb:3D0V|rcsb pdb:2ME1|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|rcsb pdb:1AIK|rcsb pdb:1DF4|rcsb pdb:1DF5|rcsb pdb:1DLB|rcsb pdb:1G9M|rcsb pdb:1GC1|rcsb pdb:1GZL|rcsb pdb:1K33|rcsb pdb:1K34|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:1RZJ|rcsb pdb:2CMR|rcsb pdb:2PV6|rcsb pdb:2XRA|rcsb pdb:3DNL|rcsb pdb:3DNN|rcsb pdb:3DNO|rcsb pdb:3IDX|rcsb pdb:3IDY|rcsb pdb:3TYG|rcsb pdb:3VIE|refseq:NP_057856.1|rcsb pdb:5HFL|rcsb pdb:4JPJ|rcsb pdb:4JPK|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)go:"GO:0042605"(peptide antigen binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-1236974|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016020"(membrane)|go:"GO:0046977"(TAP binding)|go:"GO:0009986"(cell surface)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0016032"(viral process)|reactome:R-HSA-2172127|rcsb pdb:6JTO|interpro:IPR036179|interpro:IPR037055|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1IM9|rcsb pdb:1QQD|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1EFX|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|reactome:R-HSA-6798695|mint:P10321|ensembl:ENSG00000204525|ensembl:ENSP00000365402|ensembl:ENST00000376228|refseq:NP_002108.4psi-mi:"MI:0007"(anti tag coimmunoprecipitation)comment:"DIP protein P04578 original sequence version: 85"|comment:"DIP protein P04578 original sequence version: 140"comment:"DIP protein P30504 original sequence version: 126"|author-confidence:0.82figure legend:suppl. data 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curationtaxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)-2012/07/092019/11/11rogid:0cs6c9Wi6DV3vHjKBSlqRJ8keHk11706rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606intact-crc:213AE67A87EADC94|rigid:58CQMT8iUJmei4cC87auYqYHfbEFalsemutation:53-53,94-94,192-192,215-215,224-224,346-346,470-470,580-580("MI:0118")|tandem tag:c-c("MI:0677")---psi-mi:"MI:0102"(sequence tag identification)psi-mi:"MI:0102"(sequence tag identification)3