Dataset statistics
| Number of variables | 42 |
|---|---|
| Number of observations | 1118895 |
| Missing cells | 0 |
| Missing cells (%) | 0.0% |
| Duplicate rows | 641 |
| Duplicate rows (%) | 0.1% |
| Total size in memory | 351.1 MiB |
| Average record size in memory | 329.0 B |
Variable types
| CAT | 41 |
|---|---|
| BOOL | 1 |
Negative has constant value "1118895" | Constant |
| Dataset has 641 (0.1%) duplicate rows | Duplicates |
#ID(s) interactor A has a high cardinality: 74355 distinct values | High cardinality |
ID(s) interactor B has a high cardinality: 92883 distinct values | High cardinality |
Alt. ID(s) interactor A has a high cardinality: 70060 distinct values | High cardinality |
Alt. ID(s) interactor B has a high cardinality: 88347 distinct values | High cardinality |
Alias(es) interactor A has a high cardinality: 74362 distinct values | High cardinality |
Alias(es) interactor B has a high cardinality: 92894 distinct values | High cardinality |
Interaction detection method(s) has a high cardinality: 238 distinct values | High cardinality |
Publication 1st author(s) has a high cardinality: 17589 distinct values | High cardinality |
Publication Identifier(s) has a high cardinality: 21833 distinct values | High cardinality |
Taxid interactor A has a high cardinality: 1429 distinct values | High cardinality |
Taxid interactor B has a high cardinality: 1359 distinct values | High cardinality |
Interaction type(s) has a high cardinality: 55 distinct values | High cardinality |
Interaction identifier(s) has a high cardinality: 717430 distinct values | High cardinality |
Confidence value(s) has a high cardinality: 48668 distinct values | High cardinality |
Xref(s) interactor A has a high cardinality: 149122 distinct values | High cardinality |
Xref(s) interactor B has a high cardinality: 207497 distinct values | High cardinality |
Interaction Xref(s) has a high cardinality: 6290 distinct values | High cardinality |
Annotation(s) interactor A has a high cardinality: 19228 distinct values | High cardinality |
Annotation(s) interactor B has a high cardinality: 46360 distinct values | High cardinality |
Interaction annotation(s) has a high cardinality: 103956 distinct values | High cardinality |
Host organism(s) has a high cardinality: 1860 distinct values | High cardinality |
Interaction parameter(s) has a high cardinality: 3145 distinct values | High cardinality |
Creation date has a high cardinality: 4148 distinct values | High cardinality |
Update date has a high cardinality: 1606 distinct values | High cardinality |
Checksum(s) interactor A has a high cardinality: 68073 distinct values | High cardinality |
Checksum(s) interactor B has a high cardinality: 83524 distinct values | High cardinality |
Interaction Checksum(s) has a high cardinality: 503579 distinct values | High cardinality |
Feature(s) interactor A has a high cardinality: 72669 distinct values | High cardinality |
Feature(s) interactor B has a high cardinality: 68846 distinct values | High cardinality |
Identification method participant A has a high cardinality: 107 distinct values | High cardinality |
Identification method participant B has a high cardinality: 115 distinct values | High cardinality |
Reproduction
| Analysis started | 2020-11-13 19:41:22.740826 |
|---|---|
| Analysis finished | 2020-11-13 19:43:36.102057 |
| Duration | 2 minutes and 13.36 seconds |
| Software version | pandas-profiling v2.9.0 |
| Download configuration | config.yaml |
| Distinct | 74355 |
|---|---|
| Distinct (%) | 6.6% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| uniprotkb:P62259 | 18984 |
|---|---|
| uniprotkb:Q5S007 | 4488 |
| uniprotkb:P13569 | 3721 |
| uniprotkb:P03372 | 3454 |
| uniprotkb:P42858 | 2191 |
| Other values (74350) |
| Value | Count | Frequency (%) | |
| uniprotkb:P62259 | 18984 | 1.7% | |
| uniprotkb:Q5S007 | 4488 | 0.4% | |
| uniprotkb:P13569 | 3721 | 0.3% | |
| uniprotkb:P03372 | 3454 | 0.3% | |
| uniprotkb:P42858 | 2191 | 0.2% | |
| uniprotkb:P19320 | 2066 | 0.2% | |
| uniprotkb:P05412 | 1992 | 0.2% | |
| uniprotkb:P14404 | 1926 | 0.2% | |
| uniprotkb:Q6P5F9 | 1789 | 0.2% | |
| uniprotkb:P11484 | 1773 | 0.2% | |
| Other values (74345) | 1076511 | 96.2% |
Unique
| Unique | 22097 ? |
|---|---|
| Unique (%) | 2.0% |
Length
| Max length | 33 |
|---|---|
| Median length | 16 |
| Mean length | 16.31294089 |
| Min length | 10 |
| Distinct | 92883 |
|---|---|
| Distinct (%) | 8.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| uniprotkb:P42858 | 4781 |
|---|---|
| uniprotkb:P11484 | 2725 |
| uniprotkb:P10592 | 1976 |
| uniprotkb:P10591 | 1676 |
| uniprotkb:P54253 | 1525 |
| Other values (92878) |
| Value | Count | Frequency (%) | |
| uniprotkb:P42858 | 4781 | 0.4% | |
| uniprotkb:P11484 | 2725 | 0.2% | |
| uniprotkb:P10592 | 1976 | 0.2% | |
| uniprotkb:P10591 | 1676 | 0.1% | |
| uniprotkb:P54253 | 1525 | 0.1% | |
| uniprotkb:P32589 | 1187 | 0.1% | |
| uniprotkb:P05067 | 1156 | 0.1% | |
| uniprotkb:P02829 | 940 | 0.1% | |
| uniprotkb:O00560 | 930 | 0.1% | |
| uniprotkb:Q96HA8 | 896 | 0.1% | |
| Other values (92873) | 1101103 | 98.4% |
Unique
| Unique | 28583 ? |
|---|---|
| Unique (%) | 2.6% |
Length
| Max length | 33 |
|---|---|
| Median length | 16 |
| Mean length | 16.3130678 |
| Min length | 1 |
| Distinct | 70060 |
|---|---|
| Distinct (%) | 6.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 27045 |
|---|---|
| intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631 | 18984 |
| intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9 | 4488 |
| intact:EBI-349854|uniprotkb:Q20BG8|uniprotkb:Q20BH2|uniprotkb:Q2I0A1|uniprotkb:Q2I102 | 3721 |
| intact:EBI-78473|uniprotkb:Q5T5H7|uniprotkb:Q6MZQ9|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7 | 3454 |
| Other values (70055) |
| Value | Count | Frequency (%) | |
| - | 27045 | 2.4% | |
| intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631 | 18984 | 1.7% | |
| intact:EBI-5323863|uniprotkb:A6NJU2|uniprotkb:Q6ZS50|uniprotkb:Q8NCX9 | 4488 | 0.4% | |
| intact:EBI-349854|uniprotkb:Q20BG8|uniprotkb:Q20BH2|uniprotkb:Q2I0A1|uniprotkb:Q2I102 | 3721 | 0.3% | |
| intact:EBI-78473|uniprotkb:Q5T5H7|uniprotkb:Q6MZQ9|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7 | 3454 | 0.3% | |
| intact:EBI-466029|uniprotkb:Q9UQB7 | 2191 | 0.2% | |
| intact:EBI-6189824|uniprotkb:B4DKS4|uniprotkb:E9PDD1|uniprotkb:A8K6R7|uniprotkb:Q6NUP8 | 2066 | 0.2% | |
| intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7 | 1992 | 0.2% | |
| intact:EBI-1994523|uniprotkb:G3UWT0|uniprotkb:Q9Z1L8 | 1926 | 0.2% | |
| intact:EBI-2550236 | 1789 | 0.2% | |
| Other values (70050) | 1051239 | 94.0% |
Unique
| Unique | 18971 ? |
|---|---|
| Unique (%) | 1.7% |
Length
| Max length | 4618 |
|---|---|
| Median length | 50 |
| Mean length | 63.066277 |
| Min length | 1 |
| Distinct | 88347 |
|---|---|
| Distinct (%) | 7.9% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 16150 |
|---|---|
| intact:EBI-466029|uniprotkb:Q9UQB7 | 4781 |
| intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-29890 | 2725 |
| intact:EBI-8603|uniprotkb:D6VXY0 | 1976 |
| intact:EBI-8591|uniprotkb:D6VPL2 | 1676 |
| Other values (88342) |
| Value | Count | Frequency (%) | |
| - | 16150 | 1.4% | |
| intact:EBI-466029|uniprotkb:Q9UQB7 | 4781 | 0.4% | |
| intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-29890 | 2725 | 0.2% | |
| intact:EBI-8603|uniprotkb:D6VXY0 | 1976 | 0.2% | |
| intact:EBI-8591|uniprotkb:D6VPL2 | 1676 | 0.1% | |
| intact:EBI-930964|uniprotkb:Q9UJG2|uniprotkb:Q9Y4J1|uniprotkb:Q17S02 | 1525 | 0.1% | |
| intact:EBI-8648|uniprotkb:D6W3R1 | 1187 | 0.1% | |
| intact:EBI-77613|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58 | 1156 | 0.1% | |
| intact:EBI-8659|uniprotkb:D6W3D1 | 940 | 0.1% | |
| intact:EBI-727004|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|dip:DIP-42705N|uniprotkb:O43391|uniprotkb:O00173|uniprotkb:B2R5Q7 | 930 | 0.1% | |
| Other values (88337) | 1085849 | 97.0% |
Unique
| Unique | 25310 ? |
|---|---|
| Unique (%) | 2.3% |
Length
| Max length | 4618 |
|---|---|
| Median length | 50 |
| Mean length | 65.86537879 |
| Min length | 1 |
| Distinct | 74362 |
|---|---|
| Distinct (%) | 6.6% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) | 18984 |
|---|---|
| psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym) | 4488 |
| psi-mi:cftr_human(display_long)|uniprotkb:cAMP-dependent chloride channel(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:CFTR(gene name)|psi-mi:CFTR(display_short)|uniprotkb:ABCC7(gene name synonym) | 3721 |
| psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) | 3454 |
| psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym) | 2191 |
| Other values (74357) |
| Value | Count | Frequency (%) | |
| psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) | 18984 | 1.7% | |
| psi-mi:lrrk2_human(display_long)|uniprotkb:LRRK2(gene name)|psi-mi:LRRK2(display_short)|uniprotkb:PARK8(gene name synonym)|uniprotkb:Dardarin(gene name synonym) | 4488 | 0.4% | |
| psi-mi:cftr_human(display_long)|uniprotkb:cAMP-dependent chloride channel(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 7(gene name synonym)|uniprotkb:Channel conductance-controlling ATPase(gene name synonym)|uniprotkb:CFTR(gene name)|psi-mi:CFTR(display_short)|uniprotkb:ABCC7(gene name synonym) | 3721 | 0.3% | |
| psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) | 3454 | 0.3% | |
| psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym) | 2191 | 0.2% | |
| psi-mi:vcam1_human(display_long)|uniprotkb:VCAM1(gene name)|psi-mi:VCAM1(display_short)|uniprotkb:INCAM-100(gene name synonym) | 2066 | 0.2% | |
| psi-mi:jun_human(display_long)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short) | 1992 | 0.2% | |
| psi-mi:mecom_mouse(display_long)|uniprotkb:Mds1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein homolog(gene name synonym)|uniprotkb:Mecom(gene name)|psi-mi:Mecom(display_short)|uniprotkb:Evi1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:Prdm3(gene name synonym) | 1926 | 0.2% | |
| psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) | 1789 | 0.2% | |
| psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym) | 1773 | 0.2% | |
| Other values (74352) | 1076511 | 96.2% |
Unique
| Unique | 22100 ? |
|---|---|
| Unique (%) | 2.0% |
Length
| Max length | 17832 |
|---|---|
| Median length | 197 |
| Mean length | 224.6818432 |
| Min length | 22 |
| Distinct | 92894 |
|---|---|
| Distinct (%) | 8.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym) | 4781 |
|---|---|
| psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym) | 2725 |
| psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short) | 1976 |
| psi-mi:hsp71_yeast(display_long)|uniprotkb:Heat shock protein YG100(gene name synonym)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short) | 1676 |
| psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym) | 1525 |
| Other values (92889) |
| Value | Count | Frequency (%) | |
| psi-mi:hd_human(display_long)|uniprotkb:HD(gene name synonym)|uniprotkb:Huntington disease protein(gene name synonym)|uniprotkb:HTT(gene name)|psi-mi:HTT(display_short)|uniprotkb:IT15(gene name synonym) | 4781 | 0.4% | |
| psi-mi:ssb1_yeast(display_long)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym) | 2725 | 0.2% | |
| psi-mi:hsp72_yeast(display_long)|uniprotkb:L0931(orf name)|uniprotkb:YLL024C(locus name)|uniprotkb:SSA2(gene name)|psi-mi:SSA2(display_short) | 1976 | 0.2% | |
| psi-mi:hsp71_yeast(display_long)|uniprotkb:Heat shock protein YG100(gene name synonym)|uniprotkb:YAL005C(locus name)|uniprotkb:SSA1(gene name)|psi-mi:SSA1(display_short) | 1676 | 0.1% | |
| psi-mi:atx1_human(display_long)|uniprotkb:ATXN1(gene name)|psi-mi:ATXN1(display_short)|uniprotkb:ATX1(gene name synonym)|uniprotkb:SCA1(gene name synonym)|uniprotkb:Spinocerebellar ataxia type 1 protein(gene name synonym) | 1525 | 0.1% | |
| psi-mi:hsp7f_yeast(display_long)|uniprotkb:Chaperone protein MSI3(gene name synonym)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name) | 1187 | 0.1% | |
| psi-mi:a4_human(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym) | 1156 | 0.1% | |
| psi-mi:hsp82_yeast(display_long)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short) | 940 | 0.1% | |
| psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) | 930 | 0.1% | |
| psi-mi:ntaq1_human(display_long)|uniprotkb:NTAQ1(gene name)|psi-mi:NTAQ1(display_short)|uniprotkb:C8orf32(gene name synonym)|uniprotkb:Protein NH2-terminal glutamine deamidase(gene name synonym)|uniprotkb:WDYHV motif-containing protein 1(gene name synonym)|uniprotkb:WDYHV1(gene name synonym) | 896 | 0.1% | |
| Other values (92884) | 1101103 | 98.4% |
Unique
| Unique | 28592 ? |
|---|---|
| Unique (%) | 2.6% |
Length
| Max length | 18257 |
|---|---|
| Median length | 206 |
| Mean length | 230.8483754 |
| Min length | 1 |
| Distinct | 238 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | |
|---|---|
| psi-mi:"MI:0397"(two hybrid array) | |
| psi-mi:"MI:0676"(tandem affinity purification) | |
| psi-mi:"MI:1356"(validated two hybrid) | |
| psi-mi:"MI:0096"(pull down) | |
| Other values (233) |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | 194787 | 17.4% | |
| psi-mi:"MI:0397"(two hybrid array) | 144495 | 12.9% | |
| psi-mi:"MI:0676"(tandem affinity purification) | 123586 | 11.0% | |
| psi-mi:"MI:1356"(validated two hybrid) | 92417 | 8.3% | |
| psi-mi:"MI:0096"(pull down) | 89930 | 8.0% | |
| psi-mi:"MI:1112"(two hybrid prey pooling approach) | 75433 | 6.7% | |
| psi-mi:"MI:0018"(two hybrid) | 71804 | 6.4% | |
| psi-mi:"MI:0006"(anti bait coimmunoprecipitation) | 47587 | 4.3% | |
| psi-mi:"MI:0398"(two hybrid pooling approach) | 45059 | 4.0% | |
| psi-mi:"MI:0432"(one hybrid) | 27255 | 2.4% | |
| Other values (228) | 206542 | 18.5% |
Unique
| Unique | 12 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 84 |
|---|---|
| Median length | 44 |
| Mean length | 40.81746991 |
| Min length | 22 |
| Distinct | 17589 |
|---|---|
| Distinct (%) | 1.6% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| Luck et al. (2017) | |
|---|---|
| Huttlin et al. (2017) | 58281 |
| Haenig et al. (2020) | 47294 |
| Rolland et al. (2014) | 43482 |
| Hein et al. (2015) | 30477 |
| Other values (17584) |
| Value | Count | Frequency (%) | |
| Luck et al. (2017) | 162719 | 14.5% | |
| Huttlin et al. (2017) | 58281 | 5.2% | |
| Haenig et al. (2020) | 47294 | 4.2% | |
| Rolland et al. (2014) | 43482 | 3.9% | |
| Hein et al. (2015) | 30477 | 2.7% | |
| Krogan et al. (2006) | 26574 | 2.4% | |
| Gavin et al. (2006) | 26102 | 2.3% | |
| Gong et al. (2009) | 22349 | 2.0% | |
| Fuxman et al. (2016) | 21954 | 2.0% | |
| Kislinger et al. (2006) | 21533 | 1.9% | |
| Other values (17579) | 658130 | 58.8% |
Unique
| Unique | 2778 ? |
|---|---|
| Unique (%) | 0.2% |
Length
| Max length | 38 |
|---|---|
| Median length | 19 |
| Mean length | 19.6592969 |
| Min length | 1 |
| Distinct | 21833 |
|---|---|
| Distinct (%) | 2.0% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| pubmed:32296183|imex:IM-25472 | |
|---|---|
| pubmed:28514442|doi:10.1038/nature22366|imex:IM-25778 | 58281 |
| pubmed:32814053|imex:IM-28217|doi:10.1016/j.celrep.2020.108050 | 47294 |
| imex:IM-23318|pubmed:25416956 | 43482 |
| pubmed:26496610|imex:IM-24272 | 30477 |
| Other values (21828) |
| Value | Count | Frequency (%) | |
| pubmed:32296183|imex:IM-25472 | 162719 | 14.5% | |
| pubmed:28514442|doi:10.1038/nature22366|imex:IM-25778 | 58281 | 5.2% | |
| pubmed:32814053|imex:IM-28217|doi:10.1016/j.celrep.2020.108050 | 47294 | 4.2% | |
| imex:IM-23318|pubmed:25416956 | 43482 | 3.9% | |
| pubmed:26496610|imex:IM-24272 | 30477 | 2.7% | |
| pubmed:16554755|imex:IM-15332|mint:MINT-5218454 | 26574 | 2.4% | |
| pubmed:16429126 | 26102 | 2.3% | |
| pubmed:19536198 | 22330 | 2.0% | |
| pubmed:27777270|imex:IM-25647 | 21954 | 2.0% | |
| pubmed:16615898|mint:MINT-5218505 | 21533 | 1.9% | |
| Other values (21823) | 658149 | 58.8% |
Unique
| Unique | 3686 ? |
|---|---|
| Unique (%) | 0.3% |
Length
| Max length | 102 |
|---|---|
| Median length | 29 |
| Mean length | 36.57352477 |
| Min length | 13 |
| Distinct | 1429 |
|---|---|
| Distinct (%) | 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| taxid:9606(human)|taxid:9606(Homo sapiens) | |
|---|---|
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | |
| taxid:10090(mouse)|taxid:10090(Mus musculus) | |
| taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") | 56991 |
| taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") | 52085 |
| Other values (1424) |
| Value | Count | Frequency (%) | |
| taxid:9606(human)|taxid:9606(Homo sapiens) | 603553 | 53.9% | |
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | 137067 | 12.3% | |
| taxid:10090(mouse)|taxid:10090(Mus musculus) | 78330 | 7.0% | |
| taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") | 56991 | 5.1% | |
| taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") | 52085 | 4.7% | |
| taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) | 43621 | 3.9% | |
| taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") | 28537 | 2.6% | |
| taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | 22183 | 2.0% | |
| taxid:192222(camje)|taxid:192222("Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)") | 12362 | 1.1% | |
| taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") | 8561 | 0.8% | |
| Other values (1419) | 75605 | 6.8% |
Unique
| Unique | 351 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 189 |
|---|---|
| Median length | 42 |
| Mean length | 51.02948981 |
| Min length | 31 |
| Distinct | 1359 |
|---|---|
| Distinct (%) | 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| taxid:9606(human)|taxid:9606(Homo sapiens) | |
|---|---|
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | |
| taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") | 57082 |
| taxid:10090(mouse)|taxid:10090(Mus musculus) | 56410 |
| taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") | 52144 |
| Other values (1354) |
| Value | Count | Frequency (%) | |
| taxid:9606(human)|taxid:9606(Homo sapiens) | 660309 | 59.0% | |
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | 137342 | 12.3% | |
| taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") | 57082 | 5.1% | |
| taxid:10090(mouse)|taxid:10090(Mus musculus) | 56410 | 5.0% | |
| taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") | 52144 | 4.7% | |
| taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) | 43668 | 3.9% | |
| taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") | 29072 | 2.6% | |
| taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") | 14241 | 1.3% | |
| taxid:192222(camje)|taxid:192222("Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)") | 12585 | 1.1% | |
| taxid:243276(trepa)|taxid:243276("Treponema pallidum (strain Nichols)") | 3788 | 0.3% | |
| Other values (1349) | 52254 | 4.7% |
Unique
| Unique | 355 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 189 |
|---|---|
| Median length | 42 |
| Mean length | 49.77514691 |
| Min length | 1 |
| Distinct | 55 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0915"(physical association) | |
|---|---|
| psi-mi:"MI:0914"(association) | |
| psi-mi:"MI:0407"(direct interaction) | 37128 |
| psi-mi:"MI:0403"(colocalization) | 30887 |
| psi-mi:"MI:0217"(phosphorylation reaction) | 3794 |
| Other values (50) | 4474 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0915"(physical association) | 635729 | 56.8% | |
| psi-mi:"MI:0914"(association) | 406883 | 36.4% | |
| psi-mi:"MI:0407"(direct interaction) | 37128 | 3.3% | |
| psi-mi:"MI:0403"(colocalization) | 30887 | 2.8% | |
| psi-mi:"MI:0217"(phosphorylation reaction) | 3794 | 0.3% | |
| psi-mi:"MI:0220"(ubiquitination reaction) | 681 | 0.1% | |
| psi-mi:"MI:0203"(dephosphorylation reaction) | 568 | 0.1% | |
| psi-mi:"MI:0570"(protein cleavage) | 545 | < 0.1% | |
| psi-mi:"MI:0213"(methylation reaction) | 348 | < 0.1% | |
| psi-mi:"MI:0414"(enzymatic reaction) | 341 | < 0.1% | |
| Other values (45) | 1991 | 0.2% |
Unique
| Unique | 5 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 68 |
|---|---|
| Median length | 38 |
| Mean length | 34.51186036 |
| Min length | 29 |
Source database(s)
Categorical
| Distinct | 26 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0469"(IntAct) | |
|---|---|
| psi-mi:"MI:0471"(MINT) | |
| psi-mi:"MI:0465"(DIP) | 46627 |
| psi-mi:"MI:0486"(UniProt) | 26336 |
| psi-mi:"MI:1335"(HPIDb) | 5062 |
| Other values (21) | 9919 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0469"(IntAct) | 894227 | 79.9% | |
| psi-mi:"MI:0471"(MINT) | 136724 | 12.2% | |
| psi-mi:"MI:0465"(DIP) | 46627 | 4.2% | |
| psi-mi:"MI:0486"(UniProt) | 26336 | 2.4% | |
| psi-mi:"MI:1335"(HPIDb) | 5062 | 0.5% | |
| psi-mi:"MI:1332"(bhf-ucl) | 4025 | 0.4% | |
| psi-mi:"MI:0903"(mpidb) | 1750 | 0.2% | |
| psi-mi:"MI:1262"(I2D) | 1179 | 0.1% | |
| psi-mi:"MI:0974"(InnateDB) | 852 | 0.1% | |
| psi-mi:"MI:0917"(matrixdb) | 690 | 0.1% | |
| Other values (16) | 1423 | 0.1% |
Unique
| Unique | 1 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 39 |
|---|---|
| Median length | 24 |
| Mean length | 23.65740306 |
| Min length | 20 |
| Distinct | 717430 |
|---|---|
| Distinct (%) | 64.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| intact:EBI-21364596|imex:IM-26684-50 | 1803 |
|---|---|
| intact:EBI-21360986|imex:IM-26684-48 | 1803 |
| intact:EBI-8401905|mint:MINT-4409852 | 1561 |
| intact:EBI-21302175|imex:IM-26954-3 | 1423 |
| intact:EBI-8412660|mint:MINT-4409856 | 1349 |
| Other values (717425) |
| Value | Count | Frequency (%) | |
| intact:EBI-21364596|imex:IM-26684-50 | 1803 | 0.2% | |
| intact:EBI-21360986|imex:IM-26684-48 | 1803 | 0.2% | |
| intact:EBI-8401905|mint:MINT-4409852 | 1561 | 0.1% | |
| intact:EBI-21302175|imex:IM-26954-3 | 1423 | 0.1% | |
| intact:EBI-8412660|mint:MINT-4409856 | 1349 | 0.1% | |
| intact:EBI-21301141|imex:IM-26954-1 | 1296 | 0.1% | |
| intact:EBI-8312518|mint:MINT-4409810 | 1248 | 0.1% | |
| intact:EBI-8392519|mint:MINT-4409850 | 1215 | 0.1% | |
| intact:EBI-8419242|mint:MINT-4409860 | 1088 | 0.1% | |
| intact:EBI-8429350|mint:MINT-4409862 | 1085 | 0.1% | |
| Other values (717420) | 1105024 | 98.8% |
Unique
| Unique | 681021 ? |
|---|---|
| Unique (%) | 60.9% |
Length
| Max length | 650 |
|---|---|
| Median length | 37 |
| Mean length | 36.96389474 |
| Min length | 14 |
| Distinct | 48668 |
|---|---|
| Distinct (%) | 4.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| intact-miscore:0.35 | |
|---|---|
| intact-miscore:0.56 | |
| intact-miscore:0.37 | |
| intact-miscore:0.40 | |
| intact-miscore:0.46 | 19459 |
| Other values (48663) |
| Value | Count | Frequency (%) | |
| intact-miscore:0.35 | 342555 | 30.6% | |
| intact-miscore:0.56 | 156605 | 14.0% | |
| intact-miscore:0.37 | 97323 | 8.7% | |
| intact-miscore:0.40 | 46017 | 4.1% | |
| intact-miscore:0.46 | 19459 | 1.7% | |
| intact-miscore:0.44 | 19023 | 1.7% | |
| intact-miscore:0.53 | 18055 | 1.6% | |
| intact-miscore:0.49 | 16484 | 1.5% | |
| intact-miscore:0.67 | 14228 | 1.3% | |
| intact-miscore:0.72 | 11812 | 1.1% | |
| Other values (48658) | 377334 | 33.7% |
Unique
| Unique | 9771 ? |
|---|---|
| Unique (%) | 0.9% |
Length
| Max length | 383 |
|---|---|
| Median length | 19 |
| Mean length | 24.37777182 |
| Min length | 1 |
Expansion method(s)
Categorical
| Distinct | 2 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| psi-mi:"MI:1060"(spoke expansion) |
| Value | Count | Frequency (%) | |
| - | 681021 | 60.9% | |
| psi-mi:"MI:1060"(spoke expansion) | 437874 | 39.1% |
Unique
| Unique | 0 ? |
|---|---|
| Unique (%) | 0.0% |
Length
| Max length | 33 |
|---|---|
| Median length | 1 |
| Mean length | 13.52304104 |
| Min length | 1 |
Biological role(s) interactor A
Categorical
| Distinct | 24 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0499"(unspecified role) | |
|---|---|
| psi-mi:"MI:0502"(enzyme target) | 3771 |
| psi-mi:"MI:0501"(enzyme) | 2766 |
| psi-mi:"MI:0586"(inhibitor) | 438 |
| psi-mi:"MI:0898"(putative self) | 378 |
| Other values (19) | 1685 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0499"(unspecified role) | 1109857 | 99.2% | |
| psi-mi:"MI:0502"(enzyme target) | 3771 | 0.3% | |
| psi-mi:"MI:0501"(enzyme) | 2766 | 0.2% | |
| psi-mi:"MI:0586"(inhibitor) | 438 | < 0.1% | |
| psi-mi:"MI:0898"(putative self) | 378 | < 0.1% | |
| psi-mi:"MI:0941"(competitor) | 304 | < 0.1% | |
| psi-mi:"MI:0840"(stimulator) | 225 | < 0.1% | |
| psi-mi:"MI:0684"(ancillary) | 203 | < 0.1% | |
| psi-mi:"MI:0682"(cofactor) | 184 | < 0.1% | |
| psi-mi:"MI:2274"(regulator) | 175 | < 0.1% | |
| Other values (14) | 594 | 0.1% |
Unique
| Unique | 1 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 37 |
|---|---|
| Median length | 34 |
| Mean length | 33.95344246 |
| Min length | 22 |
Biological role(s) interactor B
Categorical
| Distinct | 25 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0499"(unspecified role) | |
|---|---|
| psi-mi:"MI:0501"(enzyme) | 3638 |
| psi-mi:"MI:0502"(enzyme target) | 2943 |
| psi-mi:"MI:0941"(competitor) | 874 |
| psi-mi:"MI:0684"(ancillary) | 572 |
| Other values (20) | 1811 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0499"(unspecified role) | 1109057 | 99.1% | |
| psi-mi:"MI:0501"(enzyme) | 3638 | 0.3% | |
| psi-mi:"MI:0502"(enzyme target) | 2943 | 0.3% | |
| psi-mi:"MI:0941"(competitor) | 874 | 0.1% | |
| psi-mi:"MI:0684"(ancillary) | 572 | 0.1% | |
| psi-mi:"MI:0586"(inhibitor) | 343 | < 0.1% | |
| - | 305 | < 0.1% | |
| psi-mi:"MI:0840"(stimulator) | 252 | < 0.1% | |
| psi-mi:"MI:2274"(regulator) | 181 | < 0.1% | |
| psi-mi:"MI:0898"(putative self) | 180 | < 0.1% | |
| Other values (15) | 550 | < 0.1% |
Unique
| Unique | 0 ? |
|---|---|
| Unique (%) | 0.0% |
Length
| Max length | 37 |
|---|---|
| Median length | 34 |
| Mean length | 33.93590551 |
| Min length | 1 |
Experimental role(s) interactor A
Categorical
| Distinct | 15 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0496"(bait) | |
|---|---|
| psi-mi:"MI:0498"(prey) | |
| psi-mi:"MI:0497"(neutral component) | |
| psi-mi:"MI:0499"(unspecified role) | 36520 |
| psi-mi:"MI:0584"(fluorescence acceptor) | 594 |
| Other values (10) | 1403 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0496"(bait) | 543539 | 48.6% | |
| psi-mi:"MI:0498"(prey) | 364521 | 32.6% | |
| psi-mi:"MI:0497"(neutral component) | 172318 | 15.4% | |
| psi-mi:"MI:0499"(unspecified role) | 36520 | 3.3% | |
| psi-mi:"MI:0584"(fluorescence acceptor) | 594 | 0.1% | |
| psi-mi:"MI:0684"(ancillary) | 470 | < 0.1% | |
| psi-mi:"MI:0583"(fluorescence donor) | 462 | < 0.1% | |
| psi-mi:"MI:0898"(putative self) | 281 | < 0.1% | |
| psi-mi:"MI:0503"(self) | 71 | < 0.1% | |
| psi-mi:"MI:2334"(luminescence donor) | 42 | < 0.1% | |
| Other values (5) | 77 | < 0.1% |
Unique
| Unique | 0 ? |
|---|---|
| Unique (%) | 0.0% |
Length
| Max length | 50 |
|---|---|
| Median length | 22 |
| Mean length | 24.41483249 |
| Min length | 22 |
Experimental role(s) interactor B
Categorical
| Distinct | 15 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0498"(prey) | |
|---|---|
| psi-mi:"MI:0496"(bait) | |
| psi-mi:"MI:0497"(neutral component) | |
| psi-mi:"MI:0499"(unspecified role) | 36526 |
| psi-mi:"MI:0684"(ancillary) | 1002 |
| Other values (10) | 1634 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0498"(prey) | 542392 | 48.5% | |
| psi-mi:"MI:0496"(bait) | 364610 | 32.6% | |
| psi-mi:"MI:0497"(neutral component) | 172731 | 15.4% | |
| psi-mi:"MI:0499"(unspecified role) | 36526 | 3.3% | |
| psi-mi:"MI:0684"(ancillary) | 1002 | 0.1% | |
| psi-mi:"MI:0583"(fluorescence donor) | 601 | 0.1% | |
| psi-mi:"MI:0584"(fluorescence acceptor) | 490 | < 0.1% | |
| - | 305 | < 0.1% | |
| psi-mi:"MI:0898"(putative self) | 69 | < 0.1% | |
| psi-mi:"MI:2334"(luminescence donor) | 49 | < 0.1% | |
| Other values (5) | 120 | < 0.1% |
Unique
| Unique | 0 ? |
|---|---|
| Unique (%) | 0.0% |
Length
| Max length | 50 |
|---|---|
| Median length | 22 |
| Mean length | 24.41518999 |
| Min length | 1 |
Type(s) interactor A
Categorical
| Distinct | 22 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0326"(protein) | |
|---|---|
| psi-mi:"MI:0328"(small molecule) | 9606 |
| psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) | 5296 |
| psi-mi:"MI:0320"(ribonucleic acid) | 4234 |
| psi-mi:"MI:0319"(deoxyribonucleic acid) | 3618 |
| Other values (17) | 9752 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0326"(protein) | 1086389 | 97.1% | |
| psi-mi:"MI:0328"(small molecule) | 9606 | 0.9% | |
| psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) | 5296 | 0.5% | |
| psi-mi:"MI:0320"(ribonucleic acid) | 4234 | 0.4% | |
| psi-mi:"MI:0319"(deoxyribonucleic acid) | 3618 | 0.3% | |
| psi-mi:"MI:0327"(peptide) | 2406 | 0.2% | |
| psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) | 1854 | 0.2% | |
| psi-mi:"MI:0250"(gene) | 1841 | 0.2% | |
| psi-mi:"MI:2204"(micro rna) | 894 | 0.1% | |
| psi-mi:"MI:0608"(ribosomal rna) | 769 | 0.1% | |
| Other values (12) | 1988 | 0.2% |
Unique
| Unique | 0 ? |
|---|---|
| Unique (%) | 0.0% |
Length
| Max length | 55 |
|---|---|
| Median length | 25 |
| Mean length | 25.35176044 |
| Min length | 22 |
Type(s) interactor B
Categorical
| Distinct | 25 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0326"(protein) | |
|---|---|
| psi-mi:"MI:0319"(deoxyribonucleic acid) | 24622 |
| psi-mi:"MI:0250"(gene) | 1970 |
| psi-mi:"MI:0324"(messenger rna) | 686 |
| psi-mi:"MI:0327"(peptide) | 583 |
| Other values (20) | 3307 |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0326"(protein) | 1087727 | 97.2% | |
| psi-mi:"MI:0319"(deoxyribonucleic acid) | 24622 | 2.2% | |
| psi-mi:"MI:0250"(gene) | 1970 | 0.2% | |
| psi-mi:"MI:0324"(messenger rna) | 686 | 0.1% | |
| psi-mi:"MI:0327"(peptide) | 583 | 0.1% | |
| psi-mi:"MI:0609"(small nucleolar rna) | 486 | < 0.1% | |
| psi-mi:"MI:0608"(ribosomal rna) | 455 | < 0.1% | |
| psi-mi:"MI:0328"(small molecule) | 326 | < 0.1% | |
| - | 305 | < 0.1% | |
| psi-mi:"MI:1302"(stable complex) | 295 | < 0.1% | |
| Other values (15) | 1440 | 0.1% |
Unique
| Unique | 1 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 55 |
|---|---|
| Median length | 25 |
| Mean length | 25.32626565 |
| Min length | 1 |
| Distinct | 149122 |
|---|---|
| Distinct (%) | 13.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 28703 |
|---|---|
| go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0099400"(caveola neck)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|dip:DIP-29684N|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(ion channel binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR036322|interpro:IPR036770|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|ensembl:ENST00000298910|go:"GO:0016234"(inclusion body)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0007005"(mitochondrion organization)|ensembl:ENSG00000188906|ensembl:ENSP00000298910|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016301"(kinase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043204"(perikaryon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:1903125"(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036479"(peroxidase inhibitor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1903217"(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|interpro:IPR032675|go:"GO:0046039"(GTP metabolic process)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:0030426"(growth cone)|interpro:IPR032171|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0039706"(co-receptor binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:1904713"(beta-catenin destruction complex binding)|go:"GO:1904887"(Wnt signalosome assembly)|reactome:R-HSA-8857538|go:"GO:0007283"(spermatogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021756"(striatum development)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:1904469"|mint:Q5S007|go:"GO:0005902"(microvillus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016310"(phosphorylation)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0097487"(multivesicular body, internal vesicle)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:0000149"(SNARE binding)|go:"GO:0003779"(actin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030276"(clathrin binding)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:0030424"(axon)|rcsb pdb:5MY9|rcsb pdb:5MYC|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0000186"(activation of MAPKK activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0035640"(exploration behavior)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0070997"(neuron death)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|refseq:NP_940980.3|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:2ZEJ|rcsb pdb:3D6T|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6DLO|rcsb pdb:6DLP|go:"GO:0005654"(nucleoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0045121"(membrane raft)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR027417|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005615"(extracellular space)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0003924"(GTPase activity)|go:"GO:0015631"(tubulin binding) | 4434 |
| reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|mint:P13569|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-HSA-382556|reactome:R-HSA-5627083|reactome:R-HSA-5678895|rcsb pdb:4WZ6|go:"GO:0005829"(cytosol)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|ensembl:ENST00000003084|ensembl:ENSG00000001626|ensembl:ENSP00000003084|rcsb pdb:6O1V|rcsb pdb:6O2P|rcsb pdb:5D3F|dip:DIP-32788N|go:"GO:0017081"(chloride channel regulator activity)|rcsb pdb:5D2D|rcsb pdb:5D3E|go:"GO:0005765"(lysosomal membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0031901"(early endosome membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATPase activity)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|rcsb pdb:5TF7|rcsb pdb:5TF8|rcsb pdb:5TFA|rcsb pdb:5TFB|rcsb pdb:5TFC|rcsb pdb:5TFD|rcsb pdb:5TFF|rcsb pdb:5TFG|rcsb pdb:5TFI|rcsb pdb:5TFJ|rcsb pdb:5TGK|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0061024"(membrane organization)|rcsb pdb:5UAK|go:"GO:0051087"(chaperone binding)|go:"GO:0016853"(isomerase activity)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|rcsb pdb:6GJQ|rcsb pdb:6GJS|rcsb pdb:6GJU|rcsb pdb:6GK4|rcsb pdb:6GKD|reactome:R-HSA-9646399|interpro:IPR036640|interpro:IPR027417|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0106138"(Sec61 translocon complex binding)|rcsb pdb:6HEP|rcsb pdb:6MSM|ensembl:ENSP00000497203|ensembl:ENST00000649781|refseq:NP_000483.3|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|rcsb pdb:1NBD|rcsb pdb:1XMI|rcsb pdb:1XMJ|rcsb pdb:2BBO|rcsb pdb:2BBS|rcsb pdb:2BBT|rcsb pdb:2PZE|rcsb pdb:2PZF|rcsb pdb:2PZG|rcsb pdb:3GD7|rcsb pdb:3ISW|rcsb pdb:2LOB|go:"GO:0005769"(early endosome)|interpro:IPR025837|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport) | 3704 |
| go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:3Q95|rcsb pdb:6OWC|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR024178|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensembl:ENSG00000091831|go:"GO:0005654"(nucleoplasm)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0005496"(steroid binding)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0097550"(transcription preinitiation complex)|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:4AA6|go:"GO:0002064"(epithelial cell development)|go:"GO:0008584"(male gonad development)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|rcsb pdb:5JMM|rcsb pdb:5U2B|interpro:IPR024736|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5T0X|rcsb pdb:5TN9|rcsb pdb:5TNB|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071391"(cellular response to estrogen stimulus)|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|reactome:R-HSA-5689896|reactome:R-HSA-8866910|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6CBZ|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|go:"GO:0000790"(nuclear chromatin)|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:5AK2|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0035327"(transcriptionally active chromatin)|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|ensembl:ENST00000206249|ensembl:ENST00000338799|ensembl:ENST00000440973|ensembl:ENST00000443427|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|refseq:NP_001278159.1|refseq:NP_001278170.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:5U2D|dip:DIP-5965N|go:"GO:0005829"(cytosol)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|rcsb pdb:5UFW|rcsb pdb:5UFX|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|mint:P03372|rcsb pdb:4ZN9|rcsb pdb:4ZN7|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5HYR|reactome:R-HSA-1251985|reactome:R-HSA-383280|rcsb pdb:5AAU|rcsb pdb:5AAV|go:"GO:0051117"(ATPase binding)|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:6CZN|rcsb pdb:6D0F|go:"GO:0001223"(transcription coactivator binding)|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5ACC|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|rcsb pdb:6B0F|rcsb pdb:6CHW|rcsb pdb:6CHZ|reactome:R-HSA-8939211|reactome:R-HSA-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMU|reactome:R-HSA-9009391|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6TL3|rcsb pdb:6VVP|rcsb pdb:5W9C|rcsb pdb:5WGD|rcsb pdb:5WGQ|reactome:R-HSA-4090294|rcsb pdb:6IAR|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|rcsb pdb:5N10|reactome:R-HSA-8931987|reactome:R-HSA-8939256|interpro:IPR035500|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5T1Z|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|rcsb pdb:5W9D|reactome:R-HSA-8939902|go:"GO:0010629"(negative regulation of gene expression)|rcsb pdb:4DMA|go:"GO:0016021"(integral component of membrane)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VNN|rcsb pdb:6VPK|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|rcsb pdb:6C42|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|rcsb pdb:4O6F|refseq:XP_006715438.1|go:"GO:0005794"(Golgi apparatus)|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4XI3 | 3421 |
| go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENST00000294728|ensembl:ENST00000347652|ensembl:ENST00000370119|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000162692|ensembl:ENSP00000294728|ensembl:ENSP00000304611|ensembl:ENSP00000359137|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-877300|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0007160"(cell-matrix adhesion)|reactome:R-HSA-6785807|interpro:IPR013106(Immunoglobulin V-set)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0005178"(integrin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR036179|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0030175"(filopodium)|go:"GO:0005902"(microvillus)|go:"GO:0002102"(podosome)|go:"GO:0030183"(B cell differentiation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0050776"(regulation of immune response)|refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR003989(Vascular cell adhesion molecule-1)|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC | 2058 |
| Other values (149117) |
| Value | Count | Frequency (%) | |
| - | 28703 | 2.6% | |
| go:"GO:0007030"(Golgi organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0099400"(caveola neck)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|dip:DIP-29684N|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(ion channel binding)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|interpro:IPR036322|interpro:IPR036770|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|ensembl:ENST00000298910|go:"GO:0016234"(inclusion body)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0007005"(mitochondrion organization)|ensembl:ENSG00000188906|ensembl:ENSP00000298910|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016301"(kinase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043204"(perikaryon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:1903125"(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036479"(peroxidase inhibitor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1903217"(negative regulation of protein processing involved in protein targeting to mitochondrion)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|interpro:IPR032675|go:"GO:0046039"(GTP metabolic process)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:0030426"(growth cone)|interpro:IPR032171|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0039706"(co-receptor binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:1904713"(beta-catenin destruction complex binding)|go:"GO:1904887"(Wnt signalosome assembly)|reactome:R-HSA-8857538|go:"GO:0007283"(spermatogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021756"(striatum development)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903980"(positive regulation of microglial cell activation)|go:"GO:1904469"|mint:Q5S007|go:"GO:0005902"(microvillus)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016310"(phosphorylation)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0097487"(multivesicular body, internal vesicle)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990909"(Wnt signalosome)|go:"GO:0000149"(SNARE binding)|go:"GO:0003779"(actin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030276"(clathrin binding)|go:"GO:1902803"(regulation of synaptic vesicle transport)|go:"GO:0030424"(axon)|rcsb pdb:5MY9|rcsb pdb:5MYC|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0034211"(GTP-dependent protein kinase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0000186"(activation of MAPKK activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0035640"(exploration behavior)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0070997"(neuron death)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|refseq:NP_940980.3|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020859|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:2ZEJ|rcsb pdb:3D6T|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6DLO|rcsb pdb:6DLP|go:"GO:0005654"(nucleoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0045121"(membrane raft)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR027417|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005615"(extracellular space)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0003924"(GTPase activity)|go:"GO:0015631"(tubulin binding) | 4434 | 0.4% | |
| reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|mint:P13569|go:"GO:0009986"(cell surface)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0048240"(sperm capacitation)|go:"GO:0051454"(intracellular pH elevation)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-HSA-382556|reactome:R-HSA-5627083|reactome:R-HSA-5678895|rcsb pdb:4WZ6|go:"GO:0005829"(cytosol)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:1902161"(positive regulation of cyclic nucleotide-gated ion channel activity)|ensembl:ENST00000003084|ensembl:ENSG00000001626|ensembl:ENSP00000003084|rcsb pdb:6O1V|rcsb pdb:6O2P|rcsb pdb:5D3F|dip:DIP-32788N|go:"GO:0017081"(chloride channel regulator activity)|rcsb pdb:5D2D|rcsb pdb:5D3E|go:"GO:0005765"(lysosomal membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0031901"(early endosome membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATPase activity)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|rcsb pdb:5TF7|rcsb pdb:5TF8|rcsb pdb:5TFA|rcsb pdb:5TFB|rcsb pdb:5TFC|rcsb pdb:5TFD|rcsb pdb:5TFF|rcsb pdb:5TFG|rcsb pdb:5TFI|rcsb pdb:5TFJ|rcsb pdb:5TGK|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0061024"(membrane organization)|rcsb pdb:5UAK|go:"GO:0051087"(chaperone binding)|go:"GO:0016853"(isomerase activity)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|rcsb pdb:6GJQ|rcsb pdb:6GJS|rcsb pdb:6GJU|rcsb pdb:6GK4|rcsb pdb:6GKD|reactome:R-HSA-9646399|interpro:IPR036640|interpro:IPR027417|go:"GO:1902943"(positive regulation of voltage-gated chloride channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0106138"(Sec61 translocon complex binding)|rcsb pdb:6HEP|rcsb pdb:6MSM|ensembl:ENSP00000497203|ensembl:ENST00000649781|refseq:NP_000483.3|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR009147(Cystic fibrosis transmembrane conductance regulator)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005260"(intracellularly ATP-gated chloride channel activity)|rcsb pdb:1NBD|rcsb pdb:1XMI|rcsb pdb:1XMJ|rcsb pdb:2BBO|rcsb pdb:2BBS|rcsb pdb:2BBT|rcsb pdb:2PZE|rcsb pdb:2PZF|rcsb pdb:2PZG|rcsb pdb:3GD7|rcsb pdb:3ISW|rcsb pdb:2LOB|go:"GO:0005769"(early endosome)|interpro:IPR025837|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030301"(cholesterol transport) | 3704 | 0.3% | |
| go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:3Q95|rcsb pdb:6OWC|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR024178|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensembl:ENSG00000091831|go:"GO:0005654"(nucleoplasm)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0005496"(steroid binding)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0097550"(transcription preinitiation complex)|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:4AA6|go:"GO:0002064"(epithelial cell development)|go:"GO:0008584"(male gonad development)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|rcsb pdb:5JMM|rcsb pdb:5U2B|interpro:IPR024736|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5T0X|rcsb pdb:5TN9|rcsb pdb:5TNB|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071391"(cellular response to estrogen stimulus)|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|reactome:R-HSA-5689896|reactome:R-HSA-8866910|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6CBZ|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|go:"GO:0000790"(nuclear chromatin)|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:5AK2|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0035327"(transcriptionally active chromatin)|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|ensembl:ENST00000206249|ensembl:ENST00000338799|ensembl:ENST00000440973|ensembl:ENST00000443427|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000387500|ensembl:ENSP00000405330|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|refseq:NP_001278159.1|refseq:NP_001278170.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:5U2D|dip:DIP-5965N|go:"GO:0005829"(cytosol)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|rcsb pdb:5UFW|rcsb pdb:5UFX|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-6811558|mint:P03372|rcsb pdb:4ZN9|rcsb pdb:4ZN7|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXP|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5HYR|reactome:R-HSA-1251985|reactome:R-HSA-383280|rcsb pdb:5AAU|rcsb pdb:5AAV|go:"GO:0051117"(ATPase binding)|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:6CZN|rcsb pdb:6D0F|go:"GO:0001223"(transcription coactivator binding)|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5ACC|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019901"(protein kinase binding)|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|rcsb pdb:6B0F|rcsb pdb:6CHW|rcsb pdb:6CHZ|reactome:R-HSA-8939211|reactome:R-HSA-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMU|reactome:R-HSA-9009391|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6TL3|rcsb pdb:6VVP|rcsb pdb:5W9C|rcsb pdb:5WGD|rcsb pdb:5WGQ|reactome:R-HSA-4090294|rcsb pdb:6IAR|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|rcsb pdb:5N10|reactome:R-HSA-8931987|reactome:R-HSA-8939256|interpro:IPR035500|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5T1Z|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0004879"(nuclear receptor activity)|rcsb pdb:5W9D|reactome:R-HSA-8939902|go:"GO:0010629"(negative regulation of gene expression)|rcsb pdb:4DMA|go:"GO:0016021"(integral component of membrane)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VNN|rcsb pdb:6VPK|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|rcsb pdb:6C42|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|rcsb pdb:4O6F|refseq:XP_006715438.1|go:"GO:0005794"(Golgi apparatus)|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4XI3 | 3421 | 0.3% | |
| go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENST00000294728|ensembl:ENST00000347652|ensembl:ENST00000370119|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000162692|ensembl:ENSP00000294728|ensembl:ENSP00000304611|ensembl:ENSP00000359137|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-877300|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0007160"(cell-matrix adhesion)|reactome:R-HSA-6785807|interpro:IPR013106(Immunoglobulin V-set)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0005178"(integrin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0140039"(cell-cell adhesion in response to extracellular stimulus)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR036179|go:"GO:0071065"(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0030175"(filopodium)|go:"GO:0005902"(microvillus)|go:"GO:0002102"(podosome)|go:"GO:0030183"(B cell differentiation)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0050776"(regulation of immune response)|refseq:NP_001069.1|refseq:NP_001186763.1|refseq:NP_542413.1|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR008424(Immunoglobulin C2-set)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR003989(Vascular cell adhesion molecule-1)|rcsb pdb:1IJ9|rcsb pdb:1VCA|rcsb pdb:1VSC | 2058 | 0.2% | |
| dip:DIP-46516N|refseq:NP_067417.1|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSMUSG00000027684|ensembl:ENSMUSP00000103905|reactome:R-MMU-3214841|mint:P14404|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030900"(forebrain development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060039"(pericardium development)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0098727"(maintenance of cell number)|reactome:R-MMU-8943724|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|ensembl:ENSMUST00000108270|go:"GO:0016607"(nuclear speck)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070828"(heterochromatin organization)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030097"(hemopoiesis)|interpro:IPR036236|interpro:IPR001214(SET)|go:"GO:0042803"(protein homodimerization activity) | 1926 | 0.2% | |
| go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035976"(transcription factor AP-1 complex)|refseq:NP_002219.1|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:1902895"(positive regulation of pri-miRNA transcription by RNA polymerase II)|ensembl:ENST00000371222|reactome:R-HSA-9018519|go:"GO:0003713"(transcription coactivator activity)|dip:DIP-5961N|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0001102"(RNA polymerase II activating transcription factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0007265"(Ras protein signal transduction)|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5687128|ensembl:ENSG00000177606|ensembl:ENSP00000360266|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:0000976"(transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR015558(c-Jun Transcription Factor)|reactome:R-HSA-6796648|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|reactome:R-HSA-5617472|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8862803|go:"GO:0005719"(nuclear euchromatin)|go:"GO:0035497"(cAMP response element binding)|reactome:R-HSA-9673324|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-8943724|go:"GO:0000790"(nuclear chromatin)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0010033"(response to organic substance)|go:"GO:0006366"(transcription by RNA polymerase II)|rcsb pdb:5FV8|go:"GO:0019899"(enzyme binding)|mint:P05412|go:"GO:0001525"(angiogenesis)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0042493"(response to drug)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|rcsb pdb:5T01|go:"GO:0005634"(nucleus)|psi-mi:"MI:0326"(protein) | 1845 | 0.2% | |
| go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0046825"(regulation of protein export from nucleus)|refseq:NP_001030303.1|refseq:NP_598775.2|ensembl:ENSMUSG00000020290|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR001494(Importin-beta, N-terminal)|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|ensembl:ENSMUST00000109551|go:"GO:0000776"(kinetochore)|ensembl:ENSMUST00000020538|ensembl:ENSMUST00000102869|ensembl:ENSMUST00000102870|dip:DIP-48612N|reactome:R-MMU-68877|go:"GO:0032991"(protein-containing complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR040485|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-69273|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178|reactome:R-MMU-141444|reactome:R-MMU-5687128|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0015030"(Cajal body)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0008536"(Ran GTPase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005829"(cytosol)|refseq:XP_006514493.1|go:"GO:0005737"(cytoplasm)|interpro:IPR041123|interpro:IPR041235|reactome:R-MMU-9634638|reactome:R-MMU-9648025|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0042493"(response to drug) | 1783 | 0.2% | |
| go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding) | 1771 | 0.2% | |
| go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding) | 1658 | 0.1% | |
| Other values (149112) | 1067592 | 95.4% |
Unique
| Unique | 86223 ? |
|---|---|
| Unique (%) | 7.7% |
Length
| Max length | 16239 |
|---|---|
| Median length | 807 |
| Mean length | 1318.134188 |
| Min length | 1 |
| Distinct | 207497 |
|---|---|
| Distinct (%) | 18.5% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 29283 |
|---|---|
| go:"GO:0005776"(autophagosome)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005770"(late endosome)|go:"GO:0005634"(nucleus)|reactome:R-HSA-9022692|go:"GO:0019900"(kinase binding)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6EZ8|go:"GO:0042297"(vocal learning)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0034452"(dynactin binding)|go:"GO:0005814"(centriole)|go:"GO:0045724"(positive regulation of cilium assembly)|ensembl:ENST00000355072|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0044325"(ion channel binding)|ensembl:ENSG00000197386|ensembl:ENSP00000347184|go:"GO:0005522"(profilin binding)|dip:DIP-32492N|mint:P42858|go:"GO:0005654"(nucleoplasm)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0007030"(Golgi organization)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0047496"(vesicle transport along microtubule)|rcsb pdb:2D3X|refseq:NP_002102.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000091(Huntingtin)|interpro:IPR024613|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0016234"(inclusion body)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|rcsb pdb:6N8C|go:"GO:0005769"(early endosome)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|go:"GO:0006915"(apoptotic process)|interpro:IPR028426|rcsb pdb:2LD0|rcsb pdb:2LD2|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048487"(beta-tubulin binding)|entrezgene/locuslink:3064(identity) | 4464 |
| go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding) | 2721 |
| go:"GO:0005829"(cytosol)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_013076.1|sgd:S000003947|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-SCE-8856828|mint:P10592|dip:DIP-2265N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0000049"(tRNA binding)|go:"GO:0035719"(tRNA import into nucleus)|interpro:IPR029047|interpro:IPR029048|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|go:"GO:0016887"(ATPase activity)|go:"GO:0051082"(unfolded protein binding) | 1973 |
| go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding) | 1636 |
| Other values (207492) |
| Value | Count | Frequency (%) | |
| - | 29283 | 2.6% | |
| go:"GO:0005776"(autophagosome)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005770"(late endosome)|go:"GO:0005634"(nucleus)|reactome:R-HSA-9022692|go:"GO:0019900"(kinase binding)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1905337"(positive regulation of aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6EZ8|go:"GO:0042297"(vocal learning)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0034452"(dynactin binding)|go:"GO:0005814"(centriole)|go:"GO:0045724"(positive regulation of cilium assembly)|ensembl:ENST00000355072|go:"GO:0031587"(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0044325"(ion channel binding)|ensembl:ENSG00000197386|ensembl:ENSP00000347184|go:"GO:0005522"(profilin binding)|dip:DIP-32492N|mint:P42858|go:"GO:0005654"(nucleoplasm)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0007030"(Golgi organization)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0047496"(vesicle transport along microtubule)|rcsb pdb:2D3X|refseq:NP_002102.4|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000091(Huntingtin)|interpro:IPR024613|rcsb pdb:3IO4|rcsb pdb:3IO6|rcsb pdb:3IOR|rcsb pdb:3IOT|rcsb pdb:3IOU|rcsb pdb:3IOV|rcsb pdb:3IOW|rcsb pdb:3LRH|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0016234"(inclusion body)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1905289"(regulation of CAMKK-AMPK signaling cascade)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|rcsb pdb:6N8C|go:"GO:0005769"(early endosome)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|rcsb pdb:4FE8|rcsb pdb:4FEB|rcsb pdb:4FEC|rcsb pdb:4FED|rcsb pdb:4RAV|go:"GO:0006915"(apoptotic process)|interpro:IPR028426|rcsb pdb:2LD0|rcsb pdb:2LD2|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048487"(beta-tubulin binding)|entrezgene/locuslink:3064(identity) | 4464 | 0.4% | |
| go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|refseq:NP_010052.1|sgd:S000002388|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3GL1|mint:P11484|dip:DIP-2254N|go:"GO:0006452"(translational frameshifting)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005634"(nucleus)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0005886"(plasma membrane)|reactome:R-SCE-3371497|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0051082"(unfolded protein binding) | 2721 | 0.2% | |
| go:"GO:0005829"(cytosol)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_013076.1|sgd:S000003947|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-SCE-8856828|mint:P10592|dip:DIP-2265N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0000049"(tRNA binding)|go:"GO:0035719"(tRNA import into nucleus)|interpro:IPR029047|interpro:IPR029048|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|go:"GO:0016887"(ATPase activity)|go:"GO:0051082"(unfolded protein binding) | 1973 | 0.2% | |
| go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005844"(polysome)|go:"GO:0005524"(ATP binding)|go:"GO:0016887"(ATPase activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|refseq:NP_009396.2|sgd:S000000004|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3LCA|reactome:R-SCE-3371453|reactome:R-SCE-3371497|reactome:R-SCE-3371568|reactome:R-SCE-3371571|reactome:R-SCE-6798695|reactome:R-SCE-8856828|mint:P10591|dip:DIP-2253N|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0000049"(tRNA binding)|go:"GO:0000209"(protein polyubiquitination)|interpro:IPR029047|interpro:IPR029048|go:"GO:0035617"(stress granule disassembly)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR043129|go:"GO:0006606"(protein import into nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|rcsb pdb:5Z8I|rcsb pdb:5Z8Q|rcsb pdb:5LYN|go:"GO:0051082"(unfolded protein binding) | 1636 | 0.1% | |
| go:"GO:0005844"(polysome)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042026"(protein refolding)|refseq:NP_015219.1|sgd:S000006027|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F|mint:P32589|dip:DIP-6645N|go:"GO:0006457"(protein folding)|interpro:IPR029047|interpro:IPR029048|go:"GO:0005516"(calmodulin binding)|go:"GO:0006914"(autophagy)|interpro:IPR043129|reactome:R-SCE-3371453|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol) | 1183 | 0.1% | |
| go:"GO:0005737"(cytoplasm)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0016363"(nuclear matrix)|go:"GO:0005654"(nucleoplasm)|go:"GO:0034046"("poly(G) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051168"(nuclear export)|go:"GO:0006396"(RNA processing)|refseq:NP_000323.2|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0035176"(social behavior)|go:"GO:0003677"(DNA binding)|rcsb pdb:2M41|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000244769|ensembl:ENST00000436367|ensembl:ENSP00000244769|ensembl:ENSP00000416360|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007399"(nervous system development)|go:"GO:0048856"(anatomical structure development)|mint:P54253|dip:DIP-35353N|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR043404|refseq:NP_001121636.1|ensembl:ENSG00000124788|interpro:IPR003652(Ataxin, AXH region)|interpro:IPR020997|rcsb pdb:1OA8|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|interpro:IPR040172|interpro:IPR036096|rcsb pdb:4APT|rcsb pdb:4AQP|rcsb pdb:4J2J|rcsb pdb:4J2L|go:"GO:0043621"(protein self-association)|entrezgene/locuslink:6310(identity) | 1127 | 0.1% | |
| rcsb pdb:4HIX|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:6OC9|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048143"(astrocyte activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:0000187"(activation of MAPK activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1905945"(regulation of response to calcium ion)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0005109"(frizzled binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007613"(memory)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_000475.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR024329|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR019744|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019745|interpro:IPR019543|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR020901|go:"GO:0030424"(axon)|go:"GO:0009986"(cell surface)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005829"(cytosol)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0003677"(DNA binding)|go:"GO:0008201"(heparin binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0007155"(cell adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0016358"(dendrite development)|go:"GO:0006897"(endocytosis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045087"(innate immune response)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0007617"(mating behavior)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0002576"(platelet degranulation)|go:"GO:0006417"(regulation of translation)|go:"GO:0008542"(visual learning)|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1UO7|rcsb pdb:1UO8|rcsb pdb:1UOA|rcsb pdb:1UOI|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BOM|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:3AYU|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|rcsb pdb:2NAO|rcsb pdb:5BUO|rcsb pdb:5KK3|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|dip:DIP-574N|reactome:R-HSA-381426|reactome:R-HSA-8957275|go:"GO:0032991"(protein-containing complex)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051425"(PTB domain binding)|rcsb pdb:2MGT|rcsb pdb:2MPZ|rcsb pdb:2MXU|rcsb pdb:4PQD|go:"GO:0005768"(endosome)|rcsb pdb:4JFN|rcsb pdb:4M1C|go:"GO:0005641"(nuclear envelope lumen)|ensembl:ENST00000346798|ensembl:ENST00000348990|ensembl:ENST00000354192|ensembl:ENST00000357903|ensembl:ENST00000358918|ensembl:ENST00000440126|go:"GO:0019899"(enzyme binding)|go:"GO:0045121"(membrane raft)|rcsb pdb:4NGE|go:"GO:0005615"(extracellular space)|rcsb pdb:4ONF|rcsb pdb:4ONG|ensembl:ENSG00000142192|ensembl:ENSP00000284981|ensembl:ENSP00000345463|ensembl:ENSP00000346129|ensembl:ENSP00000350578|ensembl:ENSP00000351796|ensembl:ENSP00000387483|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|rcsb pdb:5W3P|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:5LFY|mint:P05067|go:"GO:0030900"(forebrain development)|rcsb pdb:5AM8|rcsb pdb:5AMB|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-933542|reactome:R-HSA-977225|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|rcsb pdb:4OJF|rcsb pdb:4PWQ|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:1902715"|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0010288"(response to lead ion)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0001967"(suckling behavior)|go:"GO:0005790"(smooth endoplasmic reticulum)|rcsb pdb:2MVX|rcsb pdb:5C67|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005796"(Golgi lumen)|go:"GO:0007611"(learning or memory)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0050808"(synapse organization)|go:"GO:1905893"(positive regulation of cellular response to thapsigargin)|go:"GO:1905896"(positive regulation of cellular response to tunicamycin)|go:"GO:1905898"(positive regulation of response to endoplasmic reticulum stress)|reactome:R-HSA-8862803|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:5HOY|go:"GO:0009987"(cellular process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0044304"(main axon)|go:"GO:0045177"(apical part of cell)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051124"(synaptic growth at neuromuscular junction)|go:"GO:0051233"(spindle midzone)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990761"(growth cone lamellipodium)|go:"GO:1990812"(growth cone filopodium)|rcsb pdb:2MJ1|go:"GO:0045202"(synapse)|rcsb pdb:2LOH|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070851"(growth factor receptor binding)|rcsb pdb:5VOS|rcsb pdb:5LV0|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0042535"|go:"GO:0045080"|go:"GO:0045410"|go:"GO:0050725"|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050890"(cognition)|go:"GO:0055037"(recycling endosome)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903523"(negative regulation of blood circulation)|go:"GO:1904472"(positive regulation of endothelin production)|rcsb pdb:5ONP|rcsb pdb:5ONQ|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028866|go:"GO:0046914"(transition metal ion binding)|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005623"(obsolete cell)|go:"GO:0070555"(response to interleukin-1)|reactome:R-HSA-9609523|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6SHS|rcsb pdb:6ITU|reactome:R-HSA-9660826|rcsb pdb:6RHY|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0048786"(presynaptic active zone)|go:"GO:1902894"(negative regulation of pri-miRNA transcription by RNA polymerase II)|go:"GO:1905606"(regulation of presynapse assembly)|rcsb pdb:6CO3|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:1900221"(regulation of amyloid-beta clearance)|rcsb pdb:6IYC|go:"GO:0000185"(activation of MAPKKK activity)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005769"(early endosome)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0014005"(microglia development)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032640"(tumor necrosis factor production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061903"(positive regulation of 1-phosphatidylinositol-3-kinase activity)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0097645"(amylin binding)|go:"GO:0106003"(amyloid-beta complex)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:1904022"(positive regulation of G protein-coupled receptor internalization)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0007612"(learning)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070206"(protein trimerization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|interpro:IPR037071|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:5MY4|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5OQV|rcsb pdb:5VZY|rcsb pdb:6GFI|go:"GO:0043204"(perikaryon)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071287"(cellular response to manganese ion)|rcsb pdb:5TXD|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|rcsb pdb:2Y29|rcsb pdb:2Y2A|rcsb pdb:2LNQ|rcsb pdb:6OIZ|go:"GO:0044267"(cellular protein metabolic process)|rcsb pdb:5AEF|go:"GO:0001878"(response to yeast)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|rcsb pdb:4MVI|rcsb pdb:4MVK|rcsb pdb:4MVL|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:4XXD|rcsb pdb:5CSZ|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:4MDR|rcsb pdb:3SV1|rcsb pdb:2LLM|rcsb pdb:2LP1|refseq:NP_001129488.1|refseq:NP_001129603.1|rcsb pdb:2LZ3|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|entrezgene/locuslink:351(identity) | 959 | 0.1% | |
| reactome:R-SCE-6798695|go:"GO:0005856"(cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003746"(translation elongation factor activity)|refseq:NP_009676.1|refseq:NP_015405.1|sgd:S000006284|sgd:S000000322|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|rcsb pdb:1F60|rcsb pdb:1G7C|rcsb pdb:1IJE|rcsb pdb:1IJF|rcsb pdb:2B7B|rcsb pdb:2B7C|mint:P02994|dip:DIP-2250N|reactome:R-SCE-8876725|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0006414"(translational elongation)|interpro:IPR031157|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-SCE-156842|reactome:R-SCE-3371511|go:"GO:0017048"(Rho GTPase binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0006412"(translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:1904408"(melatonin binding)|go:"GO:0005829"(cytosol)|rcsb pdb:5O8W|go:"GO:0005739"(mitochondrion)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0019003"(GDP binding)|interpro:IPR027417 | 868 | 0.1% | |
| rcsb pdb:2LSV|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|go:"GO:0005737"(cytoplasm)|go:"GO:0005524"(ATP binding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043248"(proteasome assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|refseq:NP_015084.1|sgd:S000006161|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:2CG9|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:2XD6|rcsb pdb:2WEQ|rcsb pdb:2WER|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|mint:P02829|rcsb pdb:5MGX|dip:DIP-2262N|go:"GO:0042802"(identical protein binding)|go:"GO:0006457"(protein folding)|go:"GO:0051604"(protein maturation)|go:"GO:0032204"(regulation of telomere maintenance)|reactome:R-SCE-8939211|reactome:R-SCE-9009391|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|interpro:IPR036890|interpro:IPR037196|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0009986"(cell surface)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0016887"(ATPase activity)|reactome:R-SCE-9660826|go:"GO:0000492"(box C/D snoRNP assembly)|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|reactome:R-SCE-844456|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:4ASG|go:"GO:0051082"(unfolded protein binding) | 864 | 0.1% | |
| Other values (207487) | 1073817 | 96.0% |
Unique
| Unique | 132725 ? |
|---|---|
| Unique (%) | 11.9% |
Length
| Max length | 16266 |
|---|---|
| Median length | 834 |
| Mean length | 1254.050435 |
| Min length | 1 |
| Distinct | 6290 |
|---|---|
| Distinct (%) | 0.6% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| psi-mi:"MI:0469"(intact) | |
| psi-mi:"MI:0465"(dip) | 50106 |
| go:"GO:0005634"(nucleus) | 19105 |
| go:"GO:0031965"(nuclear membrane) | 12115 |
| Other values (6285) | 81097 |
| Value | Count | Frequency (%) | |
| - | 833274 | 74.5% | |
| psi-mi:"MI:0469"(intact) | 123198 | 11.0% | |
| psi-mi:"MI:0465"(dip) | 50106 | 4.5% | |
| go:"GO:0005634"(nucleus) | 19105 | 1.7% | |
| go:"GO:0031965"(nuclear membrane) | 12115 | 1.1% | |
| go:"GO:0005739"(mitochondrion) | 9081 | 0.8% | |
| psi-mi:"MI:0471"(mint) | 6793 | 0.6% | |
| go:"GO:0005829"(cytosol) | 6087 | 0.5% | |
| go:"GO:0005792"(obsolete microsome) | 5466 | 0.5% | |
| go:"GO:0005737"(cytoplasm) | 2389 | 0.2% | |
| Other values (6280) | 51281 | 4.6% |
Unique
| Unique | 3506 ? |
|---|---|
| Unique (%) | 0.3% |
Length
| Max length | 2159 |
|---|---|
| Median length | 1 |
| Mean length | 11.47177707 |
| Min length | 1 |
| Distinct | 19228 |
|---|---|
| Distinct (%) | 1.7% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| comment:This prey protein was expressed using pDEST-AD-CHY2, a low copy number expression vector coding for an N-terminal Gal4 AD tag. | 33776 |
| comment:This prey protein was expressed using pDEST-AD-AR68, a high copy number expression vector coding for a C-terminal Gal4 AD tag. | 29060 |
| comment:This prey protein was expressed using pDEST-QZ213, a high copy number expression vector coding for an N-terminal Gal4 AD tag. | 18981 |
| comment:mint | 11253 |
| Other values (19223) |
| Value | Count | Frequency (%) | |
| - | 560936 | 50.1% | |
| comment:This prey protein was expressed using pDEST-AD-CHY2, a low copy number expression vector coding for an N-terminal Gal4 AD tag. | 33776 | 3.0% | |
| comment:This prey protein was expressed using pDEST-AD-AR68, a high copy number expression vector coding for a C-terminal Gal4 AD tag. | 29060 | 2.6% | |
| comment:This prey protein was expressed using pDEST-QZ213, a high copy number expression vector coding for an N-terminal Gal4 AD tag. | 18981 | 1.7% | |
| comment:mint | 11253 | 1.0% | |
| comment:"Stoichiometry: 1.0" | 7942 | 0.7% | |
| isoform-comment:No experimental confirmation available. | 7287 | 0.7% | |
| comment:mint|comment:homomint | 3963 | 0.4% | |
| comment:"DIP protein P03372 original sequence version: 214"|comment:"DIP protein P03372 original sequence version: 139"|comment:"DIP protein P03372 original sequence version: 167" | 3446 | 0.3% | |
| spectral count:1 | 3407 | 0.3% | |
| Other values (19218) | 438844 | 39.2% |
Unique
| Unique | 3708 ? |
|---|---|
| Unique (%) | 0.3% |
Length
| Max length | 6494 |
|---|---|
| Median length | 1 |
| Mean length | 74.51531734 |
| Min length | 1 |
| Distinct | 46360 |
|---|---|
| Distinct (%) | 4.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag. | |
| comment:"Stoichiometry: 1.0" | 9324 |
| isoform-comment:No experimental confirmation available. | 8157 |
| comment:"DIP protein P42858 original sequence version: 148"|comment:"DIP protein P42858 original sequence version: 145"|comment:"DIP protein P42858 original sequence version: 142"|comment:"DIP protein P42858 original sequence version: 157"|comment:"DIP protein P42858 original sequence version: 158"|comment:"DIP protein P42858 original sequence version: 156" | 4756 |
| Other values (46355) |
| Value | Count | Frequency (%) | |
| - | 519058 | 46.4% | |
| comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag. | 79995 | 7.1% | |
| comment:"Stoichiometry: 1.0" | 9324 | 0.8% | |
| isoform-comment:No experimental confirmation available. | 8157 | 0.7% | |
| comment:"DIP protein P42858 original sequence version: 148"|comment:"DIP protein P42858 original sequence version: 145"|comment:"DIP protein P42858 original sequence version: 142"|comment:"DIP protein P42858 original sequence version: 157"|comment:"DIP protein P42858 original sequence version: 158"|comment:"DIP protein P42858 original sequence version: 156" | 4756 | 0.4% | |
| comment:mint | 4660 | 0.4% | |
| author-confidence:A+ | 4605 | 0.4% | |
| author-confidence:B- | 4561 | 0.4% | |
| isoform-comment:No experimental confirmation available.|comment:This prey protein was expressed using pDEST-DB, a high copy number expression vector coding for an N-terminal Gal4 BD tag. | 4371 | 0.4% | |
| author-confidence:1 | 3067 | 0.3% | |
| Other values (46350) | 476341 | 42.6% |
Unique
| Unique | 22950 ? |
|---|---|
| Unique (%) | 2.1% |
Length
| Max length | 6494 |
|---|---|
| Median length | 22 |
| Mean length | 73.25544667 |
| Min length | 1 |
| Distinct | 103956 |
|---|---|
| Distinct (%) | 9.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| figure legend:Supplementary Table 9|full coverage:Only protein-protein interactions|curation depth:imex curation | |
|---|---|
| full coverage:Only protein-protein interactions|curation depth:imex curation | |
| figure legend:Supplementary table 1|full coverage:Only protein-protein interactions|curation depth:imex curation | 56486 |
| figure legend:Table S2|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation | 47188 |
| figure legend:supplementary table 2G|full coverage:Only protein-protein interactions|curation depth:imex curation | 43234 |
| Other values (103951) |
| Value | Count | Frequency (%) | |
| figure legend:Supplementary Table 9|full coverage:Only protein-protein interactions|curation depth:imex curation | 162029 | 14.5% | |
| full coverage:Only protein-protein interactions|curation depth:imex curation | 96159 | 8.6% | |
| figure legend:Supplementary table 1|full coverage:Only protein-protein interactions|curation depth:imex curation | 56486 | 5.0% | |
| figure legend:Table S2|dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease|dataset:Huntington's - Publications describing interactions involved in Huntington's disease|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.|full coverage:Only protein-protein interactions|curation depth:imex curation | 47188 | 4.2% | |
| figure legend:supplementary table 2G|full coverage:Only protein-protein interactions|curation depth:imex curation | 43234 | 3.9% | |
| - | 40860 | 3.7% | |
| figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation | 25782 | 2.3% | |
| figure legend:Table S2 | 22319 | 2.0% | |
| figure legend:Dataset EV1|full coverage:Only protein-protein interactions|curation depth:imex curation | 21954 | 2.0% | |
| figure legend:ST1|comment:mint | 21533 | 1.9% | |
| Other values (103946) | 581351 | 52.0% |
Unique
| Unique | 81099 ? |
|---|---|
| Unique (%) | 7.2% |
Length
| Max length | 4865 |
|---|---|
| Median length | 112 |
| Mean length | 151.2299733 |
| Min length | 1 |
| Distinct | 1860 |
|---|---|
| Distinct (%) | 0.2% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") | |
|---|---|
| taxid:-1(in vitro)|taxid:-1(In vitro) | |
| taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) | |
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | |
| taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) | |
| Other values (1855) |
| Value | Count | Frequency (%) | |
| taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") | 510616 | 45.6% | |
| taxid:-1(in vitro)|taxid:-1(In vitro) | 108764 | 9.7% | |
| taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) | 105942 | 9.5% | |
| taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | 62977 | 5.6% | |
| taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) | 52651 | 4.7% | |
| taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) | 47898 | 4.3% | |
| taxid:4932(baker's yeast-4l)|taxid:4932(Saccharomyces cerevisiae) | 24422 | 2.2% | |
| taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) | 15066 | 1.3% | |
| taxid:562(ecolx)|taxid:562(Escherichia coli) | 11581 | 1.0% | |
| taxid:9606(human)|taxid:9606(Homo sapiens) | 11434 | 1.0% | |
| Other values (1850) | 167544 | 15.0% |
Unique
| Unique | 428 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 213 |
|---|---|
| Median length | 72 |
| Mean length | 69.66244554 |
| Min length | 17 |
| Distinct | 3145 |
|---|---|
| Distinct (%) | 0.3% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| kd:1.2x10^-6(molar) | 31 |
| kd:3.5x10^-6(molar) | 25 |
| kd:1.54x10^-7(molar) | 24 |
| kd:1.0x10^-6(molar) | 21 |
| Other values (3140) | 5344 |
| Value | Count | Frequency (%) | |
| - | 1113450 | 99.5% | |
| kd:1.2x10^-6(molar) | 31 | < 0.1% | |
| kd:3.5x10^-6(molar) | 25 | < 0.1% | |
| kd:1.54x10^-7(molar) | 24 | < 0.1% | |
| kd:1.0x10^-6(molar) | 21 | < 0.1% | |
| kd:1.62x10^-8(molar) | 18 | < 0.1% | |
| kd:2.5x10^-6(molar) | 18 | < 0.1% | |
| kd:2.0x10^-6(molar) | 18 | < 0.1% | |
| kd:1.9x10^-6(molar) | 17 | < 0.1% | |
| kd:3.3x10^-6(molar) | 17 | < 0.1% | |
| Other values (3135) | 5256 | 0.5% |
Unique
| Unique | 2132 ? |
|---|---|
| Unique (%) | 0.2% |
Length
| Max length | 176 |
|---|---|
| Median length | 1 |
| Mean length | 1.107823344 |
| Min length | 1 |
| Distinct | 4148 |
|---|---|
| Distinct (%) | 0.4% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| 2016/06/21 | |
|---|---|
| 2017/07/07 | 58287 |
| 2020/09/11 | 47296 |
| 2014/11/26 | 43497 |
| 2015/06/11 | 30568 |
| Other values (4143) |
| Value | Count | Frequency (%) | |
| 2016/06/21 | 162830 | 14.6% | |
| 2017/07/07 | 58287 | 5.2% | |
| 2020/09/11 | 47296 | 4.2% | |
| 2014/11/26 | 43497 | 3.9% | |
| 2015/06/11 | 30568 | 2.7% | |
| 2006/05/29 | 26574 | 2.4% | |
| 2005/12/19 | 26265 | 2.3% | |
| 2011/03/10 | 22359 | 2.0% | |
| 2017/02/09 | 21994 | 2.0% | |
| 2007/03/13 | 21538 | 1.9% | |
| Other values (4138) | 657687 | 58.8% |
Unique
| Unique | 98 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 10 |
|---|---|
| Median length | 10 |
| Mean length | 10 |
| Min length | 10 |
| Distinct | 1606 |
|---|---|
| Distinct (%) | 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| 2014/10/16 | |
|---|---|
| 2019/12/13 | |
| 2019/07/12 | |
| 2020/09/18 | 47251 |
| 2017/08/10 | 39393 |
| Other values (1601) |
| Value | Count | Frequency (%) | |
| 2014/10/16 | 369941 | 33.1% | |
| 2019/12/13 | 134367 | 12.0% | |
| 2019/07/12 | 54297 | 4.9% | |
| 2020/09/18 | 47251 | 4.2% | |
| 2017/08/10 | 39393 | 3.5% | |
| 2015/02/14 | 29568 | 2.6% | |
| 2019/12/15 | 27883 | 2.5% | |
| 2018/04/06 | 26490 | 2.4% | |
| 2017/02/24 | 21853 | 2.0% | |
| 2019/05/28 | 15574 | 1.4% | |
| Other values (1596) | 352278 | 31.5% |
Unique
| Unique | 50 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 10 |
|---|---|
| Median length | 10 |
| Mean length | 10 |
| Min length | 10 |
| Distinct | 68073 |
|---|---|
| Distinct (%) | 6.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 28052 |
|---|---|
| rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 | 18984 |
| rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606 | 4488 |
| rogid:iuEu3sctRkxQlQYP4BVxV/u4DaA9606 | 3722 |
| rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 | 3465 |
| Other values (68068) |
| Value | Count | Frequency (%) | |
| - | 28052 | 2.5% | |
| rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 | 18984 | 1.7% | |
| rogid:5ZNs+6rMb4Ifz0nBk6RgYmaCFsM9606 | 4488 | 0.4% | |
| rogid:iuEu3sctRkxQlQYP4BVxV/u4DaA9606 | 3722 | 0.3% | |
| rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 | 3465 | 0.3% | |
| rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 | 2191 | 0.2% | |
| rogid:ZgZa+cLeZ2PxFhdxPut2qd7QHVo9606 | 2066 | 0.2% | |
| rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 | 1992 | 0.2% | |
| rogid:Atnfs7W0A+kPgdN2fUZ4B0JWB3c10090 | 1929 | 0.2% | |
| rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090 | 1789 | 0.2% | |
| Other values (68063) | 1050217 | 93.9% |
Unique
| Unique | 17860 ? |
|---|---|
| Unique (%) | 1.6% |
Length
| Max length | 174 |
|---|---|
| Median length | 37 |
| Mean length | 36.50516268 |
| Min length | 1 |
| Distinct | 83524 |
|---|---|
| Distinct (%) | 7.5% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 30124 |
|---|---|
| rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 | 4781 |
| rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE559292 | 2725 |
| rogid:FakCbxCBdOtSSqw2C4u76D3opS0559292 | 1976 |
| rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk559292 | 1676 |
| Other values (83519) |
| Value | Count | Frequency (%) | |
| - | 30124 | 2.7% | |
| rogid:KyttHE2o2fORsw6iTh94LB7QShA9606 | 4781 | 0.4% | |
| rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE559292 | 2725 | 0.2% | |
| rogid:FakCbxCBdOtSSqw2C4u76D3opS0559292 | 1976 | 0.2% | |
| rogid:3GvAKzWWSou3MW9HqZVxC+Wkkqk559292 | 1676 | 0.1% | |
| rogid:DodgC3h3y3QNOd7da7+XB/MPPfQ9606 | 1530 | 0.1% | |
| rogid:16yTg05haoflKGNZTW4EqC7FSs0559292 | 1187 | 0.1% | |
| rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606 | 1157 | 0.1% | |
| rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 | 940 | 0.1% | |
| rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 | 931 | 0.1% | |
| Other values (83514) | 1071868 | 95.8% |
Unique
| Unique | 23663 ? |
|---|---|
| Unique (%) | 2.1% |
Length
| Max length | 214 |
|---|---|
| Median length | 37 |
| Mean length | 36.41036827 |
| Min length | 1 |
| Distinct | 503579 |
|---|---|
| Distinct (%) | 45.0% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | 41874 |
|---|---|
| rigid:Fo+Wm15MY+EIxDwf1RBEBTU7yoM | 3606 |
| intact-crc:DEFA161B30DBD5DF | 1561 |
| rigid:JVcpCLas8d6I6fGK1Q/+ypqrw0o | 1423 |
| intact-crc:A16CFA73CF6AE082 | 1349 |
| Other values (503574) |
| Value | Count | Frequency (%) | |
| - | 41874 | 3.7% | |
| rigid:Fo+Wm15MY+EIxDwf1RBEBTU7yoM | 3606 | 0.3% | |
| intact-crc:DEFA161B30DBD5DF | 1561 | 0.1% | |
| rigid:JVcpCLas8d6I6fGK1Q/+ypqrw0o | 1423 | 0.1% | |
| intact-crc:A16CFA73CF6AE082 | 1349 | 0.1% | |
| rigid:hUbL2fgW3cjMC0bCi1Q5XasXrYA | 1296 | 0.1% | |
| intact-crc:E0A1E677EE941068 | 1248 | 0.1% | |
| intact-crc:9169064DE4E40F94|rigid:kxxLRAU3XBe6AHV6qGD2WMF/KiA | 1215 | 0.1% | |
| intact-crc:8068965A3E0EFBAC | 1088 | 0.1% | |
| intact-crc:11F865E5D9803760 | 1085 | 0.1% | |
| Other values (503569) | 1063150 | 95.0% |
Unique
| Unique | 386568 ? |
|---|---|
| Unique (%) | 34.5% |
Length
| Max length | 61 |
|---|---|
| Median length | 33 |
| Mean length | 43.96408689 |
| Min length | 1 |
| Distinct | 1 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 1.1 MiB |
| False |
|---|
| Value | Count | Frequency (%) | |
| False | 1118895 | 100.0% |
| Distinct | 72669 |
|---|---|
| Distinct (%) | 6.5% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| tandem tag:c-c | |
| gal4 activation domain:n-n | |
| gal4 activation domain:c-c | 32366 |
| tandem tag:n-n | 32163 |
| Other values (72664) |
| Value | Count | Frequency (%) | |
| - | 488993 | 43.7% | |
| tandem tag:c-c | 101358 | 9.1% | |
| gal4 activation domain:n-n | 62900 | 5.6% | |
| gal4 activation domain:c-c | 32366 | 2.9% | |
| tandem tag:n-n | 32163 | 2.9% | |
| calmodulin binding peptide plus protein a tag:c-c | 27143 | 2.4% | |
| flag tag:c-c | 20123 | 1.8% | |
| tandem tag:?-? | 18130 | 1.6% | |
| tag:?-? | 16611 | 1.5% | |
| flag tag:n-n | 14619 | 1.3% | |
| Other values (72659) | 304489 | 27.2% |
Unique
| Unique | 61292 ? |
|---|---|
| Unique (%) | 5.5% |
Length
| Max length | 4638 |
|---|---|
| Median length | 11 |
| Mean length | 16.13789855 |
| Min length | 1 |
| Distinct | 68846 |
|---|---|
| Distinct (%) | 6.2% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| gal4 dna binding domain:n-n | |
| cub:?-? | 12435 |
| tandem tag:?-? | 10599 |
| tandem tag:c-c | 4887 |
| Other values (68841) |
| Value | Count | Frequency (%) | |
| - | 814233 | 72.8% | |
| gal4 dna binding domain:n-n | 92918 | 8.3% | |
| cub:?-? | 12435 | 1.1% | |
| tandem tag:?-? | 10599 | 0.9% | |
| tandem tag:c-c | 4887 | 0.4% | |
| gal4 activation domain:n-n | 4164 | 0.4% | |
| binding-associated region:?-? | 3892 | 0.3% | |
| flag tag:?-? | 2536 | 0.2% | |
| gal4 activation domain:c-c | 2293 | 0.2% | |
| ha tag:?-? | 2088 | 0.2% | |
| Other values (68836) | 168850 | 15.1% |
Unique
| Unique | 59573 ? |
|---|---|
| Unique (%) | 5.3% |
Length
| Max length | 48415 |
|---|---|
| Median length | 1 |
| Mean length | 10.88442883 |
| Min length | 1 |
Stoichiometry(s) interactor A
Categorical
| Distinct | 31 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| 1 | 43992 |
| 2 | 2461 |
| 4 | 564 |
| 3 | 389 |
| Other values (26) | 614 |
| Value | Count | Frequency (%) | |
| - | 1070875 | 95.7% | |
| 1 | 43992 | 3.9% | |
| 2 | 2461 | 0.2% | |
| 4 | 564 | 0.1% | |
| 3 | 389 | < 0.1% | |
| 6 | 214 | < 0.1% | |
| 5 | 170 | < 0.1% | |
| 8 | 52 | < 0.1% | |
| 10 | 37 | < 0.1% | |
| 7 | 32 | < 0.1% | |
| Other values (21) | 109 | < 0.1% |
Unique
| Unique | 11 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 3 |
|---|---|
| Median length | 1 |
| Mean length | 1.000128698 |
| Min length | 1 |
Stoichiometry(s) interactor B
Categorical
| Distinct | 27 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| - | |
|---|---|
| 1 | 44086 |
| 0 | 6872 |
| 2 | 1190 |
| 3 | 194 |
| Other values (22) | 495 |
| Value | Count | Frequency (%) | |
| - | 1066058 | 95.3% | |
| 1 | 44086 | 3.9% | |
| 0 | 6872 | 0.6% | |
| 2 | 1190 | 0.1% | |
| 3 | 194 | < 0.1% | |
| 4 | 175 | < 0.1% | |
| 5 | 138 | < 0.1% | |
| 6 | 77 | < 0.1% | |
| 12 | 24 | < 0.1% | |
| 7 | 16 | < 0.1% | |
| Other values (17) | 65 | < 0.1% |
Unique
| Unique | 6 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 3 |
|---|---|
| Median length | 1 |
| Mean length | 1.000073287 |
| Min length | 1 |
| Distinct | 107 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0078"(nucleotide sequence identification) | |
|---|---|
| psi-mi:"MI:0102"(sequence tag identification) | |
| psi-mi:"MI:0396"(predetermined participant) | |
| psi-mi:"MI:0427"(Identification by mass spectrometry) | |
| psi-mi:"MI:0082"(peptide massfingerprinting) | |
| Other values (102) |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0078"(nucleotide sequence identification) | 344829 | 30.8% | |
| psi-mi:"MI:0102"(sequence tag identification) | 270172 | 24.1% | |
| psi-mi:"MI:0396"(predetermined participant) | 209412 | 18.7% | |
| psi-mi:"MI:0427"(Identification by mass spectrometry) | 82444 | 7.4% | |
| psi-mi:"MI:0082"(peptide massfingerprinting) | 51815 | 4.6% | |
| psi-mi:"MI:0113"(western blot) | 44953 | 4.0% | |
| psi-mi:"MI:0705"(anti tag western blot) | 18562 | 1.7% | |
| psi-mi:"MI:0658"(multidimensional protein identification technology) | 13784 | 1.2% | |
| psi-mi:"MI:1180"(partial DNA sequence identification) | 12845 | 1.1% | |
| psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) | 12268 | 1.1% | |
| Other values (97) | 57811 | 5.2% |
Unique
| Unique | 18 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 175 |
|---|---|
| Median length | 45 |
| Mean length | 47.51671068 |
| Min length | 27 |
| Distinct | 115 |
|---|---|
| Distinct (%) | < 0.1% |
| Missing | 0 |
| Missing (%) | 0.0% |
| Memory size | 8.5 MiB |
| psi-mi:"MI:0078"(nucleotide sequence identification) | |
|---|---|
| psi-mi:"MI:0102"(sequence tag identification) | |
| psi-mi:"MI:0396"(predetermined participant) | |
| psi-mi:"MI:0427"(Identification by mass spectrometry) | |
| psi-mi:"MI:0082"(peptide massfingerprinting) | |
| Other values (110) |
| Value | Count | Frequency (%) | |
| psi-mi:"MI:0078"(nucleotide sequence identification) | 344123 | 30.8% | |
| psi-mi:"MI:0102"(sequence tag identification) | 271349 | 24.3% | |
| psi-mi:"MI:0396"(predetermined participant) | 202910 | 18.1% | |
| psi-mi:"MI:0427"(Identification by mass spectrometry) | 90640 | 8.1% | |
| psi-mi:"MI:0082"(peptide massfingerprinting) | 51947 | 4.6% | |
| psi-mi:"MI:0113"(western blot) | 44609 | 4.0% | |
| psi-mi:"MI:0705"(anti tag western blot) | 17689 | 1.6% | |
| psi-mi:"MI:0658"(multidimensional protein identification technology) | 13857 | 1.2% | |
| psi-mi:"MI:1180"(partial DNA sequence identification) | 12845 | 1.1% | |
| psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) | 12279 | 1.1% | |
| Other values (105) | 56647 | 5.1% |
Unique
| Unique | 22 ? |
|---|---|
| Unique (%) | < 0.1% |
Length
| Max length | 175 |
|---|---|
| Median length | 45 |
| Mean length | 47.5568333 |
| Min length | 1 |
Pearson's r
The Pearson's correlation coefficient (r) is a measure of linear correlation between two variables. It's value lies between -1 and +1, -1 indicating total negative linear correlation, 0 indicating no linear correlation and 1 indicating total positive linear correlation. Furthermore, r is invariant under separate changes in location and scale of the two variables, implying that for a linear function the angle to the x-axis does not affect r.To calculate r for two variables X and Y, one divides the covariance of X and Y by the product of their standard deviations.
Spearman's ρ
The Spearman's rank correlation coefficient (ρ) is a measure of monotonic correlation between two variables, and is therefore better in catching nonlinear monotonic correlations than Pearson's r. It's value lies between -1 and +1, -1 indicating total negative monotonic correlation, 0 indicating no monotonic correlation and 1 indicating total positive monotonic correlation.To calculate ρ for two variables X and Y, one divides the covariance of the rank variables of X and Y by the product of their standard deviations.
Kendall's τ
Similarly to Spearman's rank correlation coefficient, the Kendall rank correlation coefficient (τ) measures ordinal association between two variables. It's value lies between -1 and +1, -1 indicating total negative correlation, 0 indicating no correlation and 1 indicating total positive correlation.To calculate τ for two variables X and Y, one determines the number of concordant and discordant pairs of observations. τ is given by the number of concordant pairs minus the discordant pairs divided by the total number of pairs.
Phik (φk)
Phik (φk) is a new and practical correlation coefficient that works consistently between categorical, ordinal and interval variables, captures non-linear dependency and reverts to the Pearson correlation coefficient in case of a bivariate normal input distribution. There is extensive documentation available here.Cramér's V (φc)
Cramér's V is an association measure for nominal random variables. The coefficient ranges from 0 to 1, with 0 indicating independence and 1 indicating perfect association. The empirical estimators used for Cramér's V have been proved to be biased, even for large samples. We use a bias-corrected measure that has been proposed by Bergsma in 2013 that can be found here.First rows
| #ID(s) interactor A | ID(s) interactor B | Alt. ID(s) interactor A | Alt. ID(s) interactor B | Alias(es) interactor A | Alias(es) interactor B | Interaction detection method(s) | Publication 1st author(s) | Publication Identifier(s) | Taxid interactor A | Taxid interactor B | Interaction type(s) | Source database(s) | Interaction identifier(s) | Confidence value(s) | Expansion method(s) | Biological role(s) interactor A | Biological role(s) interactor B | Experimental role(s) interactor A | Experimental role(s) interactor B | Type(s) interactor A | Type(s) interactor B | Xref(s) interactor A | Xref(s) interactor B | Interaction Xref(s) | Annotation(s) interactor A | Annotation(s) interactor B | Interaction annotation(s) | Host organism(s) | Interaction parameter(s) | Creation date | Update date | Checksum(s) interactor A | Checksum(s) interactor B | Interaction Checksum(s) | Negative | Feature(s) interactor A | Feature(s) interactor B | Stoichiometry(s) interactor A | Stoichiometry(s) interactor B | Identification method participant A | Identification method participant B | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | uniprotkb:P49418 | uniprotkb:O43426 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:EBI-2821539|uniprotkb:O43425|uniprotkb:O94984|uniprotkb:Q4KMR1 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:synj1_human(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121552|mint:MINT-16056 | intact-miscore:0.56 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-376294(identity) | go:"GO:0007612"(learning)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43426|interpro:IPR034971|interpro:IPR034972|go:"GO:0007420"(brain development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0012506"(vesicle membrane)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0097060"(synaptic membrane)|reactome:R-HSA-8856828|refseq:XP_016883989.1|reactome:R-HSA-1660499|reactome:R-HSA-1855183|reactome:R-HSA-1855204|ensembl:ENSP00000349903|go:"GO:0098793"(presynapse)|go:"GO:0061024"(membrane organization)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030117"(membrane coat)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0048489"(synaptic vesicle transport)|ensembl:ENST00000357345|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0003723"(RNA binding)|refseq:NP_001153774.1|refseq:NP_001153778.1|refseq:NP_003886.3|refseq:NP_982271.2|ensembl:ENSG00000159082|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|rcsb pdb:1W80|rcsb pdb:2DNR|rcsb pdb:2VJ0|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR035979|interpro:IPR036691|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|mint:MINT-376287(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms|comment:"Stoichiometry: 1.0" | comment:"Stoichiometry: 1.0" | comment:homomint|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606 | intact-crc:F4234557A3B54840|rigid:n+UcEH4PPLkFnIyvBiXrLefK/xU | False | binding-associated region:626-695(MINT-376295) | binding-associated region:1063-1070(MINT-376288) | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0078"(nucleotide sequence identification) |
| 1 | uniprotkb:P49418 | intact:EBI-7121639 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:MINT-8094608 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:vrparrvlw(display_short)|psi-mi:EBI-7121639(display_long) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121634|mint:MINT-8094596 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0327"(peptide) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094601(identity) | mint:MINT-8094610(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | comment:mint|no-uniprot-update: | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:lPy6gBhpgvyGSYgOqeHbjcqBtMQ-2 | intact-crc:880913D9000BF26E|rigid:iRObbQsaUeX0PxuKeQwZ73s8iKU | False | binding-associated region:626-695(MINT-8094602) | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0083"(peptide synthesis) |
| 2 | uniprotkb:P49418 | intact:EBI-7121654 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:MINT-8094645 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:hrpvrraap(display_short)|psi-mi:EBI-7121654(display_long) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121659|mint:MINT-8094627 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0327"(peptide) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094629(identity) | mint:MINT-8094647(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | comment:mint|no-uniprot-update: | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:GsDnsVmAo8ZZoKTZ4/uDb2x+h3c-2 | intact-crc:B68245E1F0508124|rigid:SlinPP5vIczFOGZjelrO+IXJq1s | False | binding-associated region:626-695(MINT-8094630) | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0083"(peptide synthesis) |
| 3 | uniprotkb:P49418 | intact:EBI-7121715 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:MINT-8094663 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:vrptraada(display_short)|psi-mi:EBI-7121715(display_long) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121710|mint:MINT-8094651 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0327"(peptide) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094653(identity) | mint:MINT-8094665(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | comment:mint|no-uniprot-update: | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:M+f6GE3SQXrMBiIVttW1MKhz3M0-2 | intact-crc:8F7F46DF027DF34E|rigid:uiWbDe6gaj1XcnJXNxuLLq2l/m4 | False | binding-associated region:626-695(MINT-8094654) | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0083"(peptide synthesis) |
| 4 | intact:EBI-7121765 | uniprotkb:P49418 | intact:MINT-8094691 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | psi-mi:xrprrghal(display_short)|psi-mi:EBI-7121765(display_long) | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121760|mint:MINT-8094677 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0327"(peptide) | psi-mi:"MI:0326"(protein) | mint:MINT-8094693(identity) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094679(identity) | - | comment:mint|no-uniprot-update: | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:cilZXZ3YLDI1s7n8WNRyUE6EnJQ-2 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | intact-crc:2EF43A66D9B2D428|rigid:/ki1zA46M4Q+rHcjCcxNhhk+5Xw | False | - | binding-associated region:626-695(MINT-8094680) | - | - | psi-mi:"MI:0083"(peptide synthesis) | psi-mi:"MI:0078"(nucleotide sequence identification) |
| 5 | uniprotkb:P49418 | intact:EBI-7121785 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:MINT-8094718 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:hrptrskla(display_short)|psi-mi:EBI-7121785(display_long) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121780|mint:MINT-8094706 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0327"(peptide) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094708(identity) | mint:MINT-8094720(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | comment:mint|no-uniprot-update: | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:Q9S7HY0OYKNz5U6ndWhu91PBN5Q-2 | intact-crc:84BF0FF8155AE7F8|rigid:XLOVWM25uJw3qiUhKe6tGNH97NE | False | binding-associated region:626-695(MINT-8094709) | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0083"(peptide synthesis) |
| 6 | intact:EBI-7121821 | uniprotkb:P49418 | intact:MINT-8094732 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | psi-mi:krpprdgtl(display_short)|psi-mi:EBI-7121821(display_long) | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121816|mint:MINT-8094722 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0327"(peptide) | psi-mi:"MI:0326"(protein) | mint:MINT-8094734(identity) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094724(identity) | - | comment:mint|no-uniprot-update: | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:EBbNcr0zagot59cukEv+Me2oOy4-2 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | intact-crc:830DCFFA177D7718|rigid:JRSHO660pb1Xran2F9HWsNTty4E | False | - | binding-associated region:626-695(MINT-8094725) | - | - | psi-mi:"MI:0083"(peptide synthesis) | psi-mi:"MI:0078"(nucleotide sequence identification) |
| 7 | uniprotkb:P49418 | intact:EBI-7121875 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | intact:MINT-8094747 | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:qrplrrprm(display_short)|psi-mi:EBI-7121875(display_long) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121870|mint:MINT-8094737 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0327"(peptide) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094739(identity) | mint:MINT-8094749(identity) | - | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | comment:mint|no-uniprot-update: | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | rogid:+PG7mBSIIqI0Qjrscg1Dca7xq4E-2 | intact-crc:EBBB881A8816BA19|rigid:WzBj7stdRfHpLxVuhfndNR9eonc | False | binding-associated region:626-695(MINT-8094740) | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0083"(peptide synthesis) |
| 8 | intact:EBI-7121931 | uniprotkb:P49418 | intact:MINT-8094812 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | psi-mi:rrprrslpe(display_short)|psi-mi:EBI-7121931(display_long) | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121926|mint:MINT-8094793 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0327"(peptide) | psi-mi:"MI:0326"(protein) | mint:MINT-8094814(identity) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094795(identity) | - | comment:mint|no-uniprot-update: | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:mzrTgOnke4NRW+G9BPdWpU6Lhec-2 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | intact-crc:DC0C4486AEA6B83F|rigid:GTdqKccRaAT8WnHgZCAJQsSmYsE | False | - | binding-associated region:626-695(MINT-8094796) | - | - | psi-mi:"MI:0083"(peptide synthesis) | psi-mi:"MI:0078"(nucleotide sequence identification) |
| 9 | intact:EBI-7121906 | uniprotkb:P49418 | intact:MINT-8094788 | intact:EBI-7121510|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0 | psi-mi:tpkrppril(display_short)|psi-mi:EBI-7121906(display_long) | psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym) | psi-mi:"MI:0084"(phage display) | Cestra et al. (1999) | pubmed:10542231|mint:MINT-5211933 | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0471"(MINT) | intact:EBI-7121911|mint:MINT-8094755 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0327"(peptide) | psi-mi:"MI:0326"(protein) | mint:MINT-8094790(identity) | rcsb pdb:5M5S|dip:DIP-40729N|reactome:R-HSA-8856828|ensembl:ENST00000325590|ensembl:ENST00000356264|ensembl:ENSG00000078053|ensembl:ENSP00000317441|ensembl:ENSP00000348602|go:"GO:0005829"(cytosol)|go:"GO:0061024"(membrane organization)|mint:P49418|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:5M61|go:"GO:0005543"(phospholipid binding)|go:"GO:0031256"(leading edge membrane)|interpro:IPR035470|go:"GO:0005886"(plasma membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR036028|go:"GO:0015629"(actin cytoskeleton)|refseq:NP_001626.1|interpro:IPR003005(Amphiphysin)|rcsb pdb:4ATM|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR003017(Amphiphysin, isoform 1)|refseq:NP_647477.1|rcsb pdb:3SOG|rcsb pdb:1UTC|interpro:IPR001452(Src homology-3)|rcsb pdb:1KY7|interpro:IPR004148(BAR)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0006897"(endocytosis)|interpro:IPR027267|mint:MINT-8094757(identity) | - | comment:mint|no-uniprot-update: | function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms | figure legend:F1 F2|comment:domino|comment:mint | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2001/01/10 | 2014/10/16 | rogid:Sbd4rq4/EaxV04gaweZHEWSw2hI-2 | rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606 | intact-crc:D4B9F42A78EEEAD3|rigid:FkC6ZpD/4st+D9Zvy2EdtJeUXxA | False | - | binding-associated region:626-695(MINT-8094758) | - | - | psi-mi:"MI:0083"(peptide synthesis) | psi-mi:"MI:0078"(nucleotide sequence identification) |
Last rows
| #ID(s) interactor A | ID(s) interactor B | Alt. ID(s) interactor A | Alt. ID(s) interactor B | Alias(es) interactor A | Alias(es) interactor B | Interaction detection method(s) | Publication 1st author(s) | Publication Identifier(s) | Taxid interactor A | Taxid interactor B | Interaction type(s) | Source database(s) | Interaction identifier(s) | Confidence value(s) | Expansion method(s) | Biological role(s) interactor A | Biological role(s) interactor B | Experimental role(s) interactor A | Experimental role(s) interactor B | Type(s) interactor A | Type(s) interactor B | Xref(s) interactor A | Xref(s) interactor B | Interaction Xref(s) | Annotation(s) interactor A | Annotation(s) interactor B | Interaction annotation(s) | Host organism(s) | Interaction parameter(s) | Creation date | Update date | Checksum(s) interactor A | Checksum(s) interactor B | Interaction Checksum(s) | Negative | Feature(s) interactor A | Feature(s) interactor B | Stoichiometry(s) interactor A | Stoichiometry(s) interactor B | Identification method participant A | Identification method participant B | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1118885 | uniprotkb:P04849-PRO_0000039379 | uniprotkb:P04849-PRO_0000039380 | intact:EBI-26302374 | intact:EBI-26302379 | psi-mi:pro_0000039379(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short) | psi-mi:pro_0000039380(display_long)|uniprotkb:F(gene name)|psi-mi:F(display_short) | psi-mi:"MI:0114"(x-ray crystallography) | Welch et al. (2012) | imex:IM-28357|pubmed:23012473 | taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)") | taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)") | psi-mi:"MI:0915"(physical association) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302357|wwpdb:4GIP|imex:IM-28357-1 | intact-miscore:0.40 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | intact:EBI-26302359(chain-parent) | uniprotkb:P04849(chain-parent) | - | - | - | figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/17 | rogid:j18699Ed29miQ2sSyoGew4jGL8U11208 | rogid:Zfmx6vvpdcvCVtuntaSGZ4uWUZI11208 | rigid:Usx80fpK2Qb32CmxT4Ppm+reFCQ | False | binding-associated region:1-81 | binding-associated region:1-377|his tag:c-c|tag:c-c | 3 | 3 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118886 | uniprotkb:P15170 | uniprotkb:P62495 | intact:EBI-948993|uniprotkb:Q96GF2|uniprotkb:J3KQG6 | intact:EBI-750990|uniprotkb:B2R6B4|uniprotkb:D3DQC1|uniprotkb:P46055|uniprotkb:Q5M7Z7|uniprotkb:Q96CG1|intact:EBI-1047744 | psi-mi:erf3a_human(display_long)|uniprotkb:ERF3A(gene name synonym)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short) | psi-mi:erf1_human(display_long)|uniprotkb:ERF1(gene name synonym)|uniprotkb:Protein Cl1(gene name synonym)|uniprotkb:RF1(gene name synonym)|uniprotkb:SUP45L1(gene name synonym)|uniprotkb:TB3-1(gene name synonym)|uniprotkb:ETF1(gene name)|psi-mi:ETF1(display_short) | psi-mi:"MI:0410"(3D electron microscopy) | Taylor et al. (2012) | imex:IM-28363|pubmed:23091004 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302415|wwpdb:3J5Y|emdb:EMD-5801|imex:IM-28363-1 | intact-miscore:0.64 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:3J5Y|rcsb pdb:5LZT|ensembl:ENST00000420576|ensembl:ENST00000434724|ensembl:ENST00000439887|ensembl:ENST00000563468|ensembl:ENSP00000398131|ensembl:ENSP00000399539|ensembl:ENSP00000408399|ensembl:ENSP00000454351|rcsb pdb:4D61|go:"GO:0006449"(regulation of translational termination)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0005829"(cytosol)|go:"GO:0018444"(translation release factor complex)|mint:P15170|go:"GO:0003723"(RNA binding)|interpro:IPR031157|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003747"(translation release factor activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0006479"(protein methylation)|refseq:NP_001123479.1|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|rcsb pdb:3E1Y|ensembl:ENSG00000103342|refseq:NP_001123478.1|go:"GO:0006412"(translation)|reactome:R-HSA-9010553|rcsb pdb:3KUI|interpro:IPR027417|rcsb pdb:5HXB|reactome:R-HSA-72764|reactome:R-HSA-975956|reactome:R-HSA-975957 | go:"GO:0005737"(cytoplasm)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR004403(Peptide chain release factor eRF/aRF subunit 1)|interpro:IPR024049|rcsb pdb:2KTU|rcsb pdb:2KTV|rcsb pdb:2LGT|rcsb pdb:2LLX|rcsb pdb:3E1Y|rcsb pdb:3J5Y|ensembl:ENSP00000353741|ensembl:ENST00000360541|refseq:NP_004721.1|refseq:NP_001243231.1|reactome:R-HSA-9010553|rcsb pdb:5LZT|rcsb pdb:5LZU|refseq:NP_001278903.1|refseq:NP_001278904.1|refseq:XP_005271978.1|interpro:IPR029064|ensembl:ENST00000499810|rcsb pdb:5LZV|ensembl:ENSG00000120705|ensembl:ENSP00000421288|rcsb pdb:3JAG|rcsb pdb:3JAH|rcsb pdb:3JAI|mint:P62495|interpro:IPR042226|rcsb pdb:4D5N|rcsb pdb:4D61|rcsb pdb:5A8L|go:"GO:1990825"(sequence-specific mRNA binding)|rcsb pdb:6D90|rcsb pdb:2MQ6|rcsb pdb:2MQ9|reactome:R-HSA-72764|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0008079"(translation termination factor activity)|go:"GO:0043022"(ribosome binding)|rcsb pdb:1DT9|rcsb pdb:2HST|go:"GO:0006415"(translational termination)|go:"GO:0018444"(translation release factor complex)|go:"GO:0016149"(translation release factor activity, codon specific)|go:"GO:0002184"(cytoplasmic translational termination)|rcsb pdb:6IP8 | - | - | - | figure legend:Fig 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/17 | rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 | rogid:vUI2Eq2wx++5VxZ2MK1EQ0jnWMI9606 | rigid:otY7vxMHvTdCYV3mXIPgpNcSeXk | False | binding-associated region:69-496 | binding-associated region:7-420 | 1 | 1 | psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) | psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) |
| 1118887 | uniprotkb:I0CES9 | uniprotkb:B4YNG0 | intact:EBI-26302445 | intact:EBI-26302437 | psi-mi:i0ces9_9viru(display_long)|uniprotkb:Sputnik3_R18(orf name) | psi-mi:capsd_sptnk(display_long)|uniprotkb:ORF20(orf name) | psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction) | Zhang et al. (2012) | pubmed:23091035|imex:IM-28358 | taxid:1133032(Sputnik virophage 3)|taxid:1133032(Sputnik virophage 3) | taxid:543939(Sputnik virophage)|taxid:543939(Sputnik virophage) | psi-mi:"MI:0915"(physical association) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302434|wwpdb:3J26|emdb:EMD-5495|imex:IM-28358-1 | intact-miscore:0.32 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:3J26 | refseq:YP_002122381.1|rcsb pdb:3J26|go:"GO:0019028"(viral capsid) | - | - | - | figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:5757(acapo)|taxid:5757(Acanthamoeba polyphaga) | - | 2020/09/17 | 2020/09/17 | rogid:XVToqQ/VXteviqtNBOjE2DbSfv81133032 | rogid:MUM/YhbIoTQLrDSJ+EQyV8zDg4Y543939 | rigid:5hhqM5aMLCkjojsVhWzG03L/iEc | False | - | binding-associated region:1-508 | 1 | 13 | psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) | psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) |
| 1118888 | uniprotkb:Q12285 | uniprotkb:Q12285 | intact:EBI-34904|uniprotkb:D6W1V6 | intact:EBI-34904|uniprotkb:D6W1V6 | psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym) | psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym) | psi-mi:"MI:0114"(x-ray crystallography) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302650|wwpdb:4A20|imex:IM-28359-1 | intact-miscore:0.44 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU | go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU | - | crc64:CE6FC4282E0E472C | crc64:CE6FC4282E0E472C | figure legend:Table S2|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") | - | 2020/09/17 | 2020/09/17 | rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 | rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 | rigid:p95S+N5uZkDbF8FS2Q2uWnHS+yQ | False | binding-associated region:70-152(IPR000626)|his tag:n-n | binding-associated region:70-152(IPR000626)|his tag:n-n | 2 | 0 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118889 | uniprotkb:Q12118 | uniprotkb:Q12118 | intact:EBI-31784|uniprotkb:D6W273 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:1103"(solution state nmr) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302663|wwpdb:4ASV|imex:IM-28359-3 | intact-miscore:0.59 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:33539B74F742BD3C | crc64:33539B74F742BD3C | figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/17 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:Ab6ImX1QHM8e04eb1/cY6/oIgqA | False | his tag:n-n|binding-associated region:1-78 | his tag:n-n|binding-associated region:1-78 | 2 | 0 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118890 | uniprotkb:Q12285 | uniprotkb:Q12118 | intact:EBI-34904|uniprotkb:D6W1V6 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:1103"(solution state nmr) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302669|wwpdb:4ASW|imex:IM-28359-5 | intact-miscore:0.95 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:CE6FC4282E0E472C | crc64:33539B74F742BD3C | figure legend:Figure S1A|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/21 | rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y | False | binding-associated region:70-152(IPR000626) | binding-associated region:1-78|15n label:?-? | 1 | 2 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118891 | uniprotkb:Q12118 | uniprotkb:Q12118 | intact:EBI-31784|uniprotkb:D6W273 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:1103"(solution state nmr) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26355058|imex:IM-28359-9 | intact-miscore:0.59 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:33539B74F742BD3C | crc64:33539B74F742BD3C | figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/21 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:mmtD4irrtiIV6dsz3UoDRum1HlU | False | his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-? | his tag:n-n|binding-associated region:1-78 | 1 | 1 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118892 | uniprotkb:Q12118 | uniprotkb:Q12118 | intact:EBI-31784|uniprotkb:D6W273 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:1103"(solution state nmr) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26355075|imex:IM-28359-11 | intact-miscore:0.59 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:33539B74F742BD3C | crc64:33539B74F742BD3C | figure legend:Fig 1, Table S1|comment:Experiments on mixed 13C/15N- and unlabeled Sgt2_NT dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/21 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:mmtD4irrtiIV6dsz3UoDRum1HlU | False | his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-? | his tag:n-n|binding-associated region:1-78|13c label:?-?|15n label:?-? | 1 | 1 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118893 | uniprotkb:Q12285 | uniprotkb:Q12118 | intact:EBI-34904|uniprotkb:D6W1V6 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:1103"(solution state nmr) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26355105|imex:IM-28359-13 | intact-miscore:0.95 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:CE6FC4282E0E472C | crc64:33539B74F742BD3C | figure legend:Figure S1B|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2020/09/17 | 2020/09/21 | rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y | False | binding-associated region:70-152(IPR000626)|15n label:?-? | binding-associated region:1-78 | 1 | 2 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
| 1118894 | uniprotkb:Q12285 | uniprotkb:Q12118 | intact:EBI-34904|uniprotkb:D6W1V6 | intact:EBI-31784|uniprotkb:D6W273 | psi-mi:mdy2_yeast(display_long)|uniprotkb:GET5(gene name synonym)|uniprotkb:Golgi to ER traffic protein 5(gene name synonym)|uniprotkb:YOL111C(locus name)|uniprotkb:MDY2(gene name)|psi-mi:MDY2(display_short)|uniprotkb:TMA24(gene name synonym)|uniprotkb:Mating-deficient protein 2(gene name synonym)|uniprotkb:Translation machinery-associated protein 24(gene name synonym) | psi-mi:sgt2_yeast(display_long)|uniprotkb:Viral protein U-binding protein(gene name synonym)|uniprotkb:SGT/UBP(gene name synonym)|uniprotkb:SGT2(gene name)|psi-mi:SGT2(display_short)|uniprotkb:UNF346(orf name)|uniprotkb:YOR007C(locus name) | psi-mi:"MI:0065"(isothermal titration calorimetry) | Simon et al. (2013) | pubmed:23297211|imex:IM-28359 | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | psi-mi:"MI:0407"(direct interaction) | psi-mi:"MI:0465"(DIP) | intact:EBI-26302723|imex:IM-28359-7 | intact-miscore:0.95 | - | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|go:"GO:0010494"(cytoplasmic stress granule)|rcsb pdb:3ZDM|interpro:IPR029071|rcsb pdb:4PWX|mint:Q12285|dip:DIP-1982N|interpro:IPR031765|go:"GO:0005737"(cytoplasm)|interpro:IPR040474|rcsb pdb:2LXA|rcsb pdb:2LXC|rcsb pdb:4A20|rcsb pdb:4ASW|rcsb pdb:4GOC|rcsb pdb:5BW8|rcsb pdb:5BWK|rcsb pdb:2LNZ|rcsb pdb:3VEJ|go:"GO:0005634"(nucleus)|go:"GO:0072380"(TRC complex)|go:"GO:0000753"(cell morphogenesis involved in conjugation with cellular fusion)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0045048"(protein insertion into ER membrane)|refseq:NP_014530.1|sgd:S000005471|interpro:IPR000626(Ubiquitin)|rcsb pdb:2WPV|rcsb pdb:3LKU | go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|rcsb pdb:3ZDM|rcsb pdb:5LYN|rcsb pdb:5LYP|dip:DIP-1983N|mint:Q12118|interpro:IPR032374|go:"GO:0060090"(molecular adaptor activity)|reactome:R-SCE-9609523|go:"GO:0005737"(cytoplasm)|rcsb pdb:2LXB|rcsb pdb:2LXC|rcsb pdb:4ASV|rcsb pdb:4ASW|go:"GO:0072380"(TRC complex)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0009408"(response to heat)|refseq:NP_014649.1|sgd:S000005533|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR013026(Tetratricopeptide region)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734 | - | crc64:CE6FC4282E0E472C | crc64:33539B74F742BD3C | figure legend:Fig 2, Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | kd:0.11x10^-6(molar) | 2020/09/17 | 2020/09/21 | rogid:lKhHoZ+UA1ZcX8TOoZMgJX+fzI0559292 | rogid:u4qztYWJIAVQOzZGnkLFnO3S2NA559292 | rigid:1Dk8Lg6VdaPv77e3vLq+FdCPd3Y | False | binding-associated region:70-152(IPR000626) | binding-associated region:1-78|mutation disrupting interaction strength:38-38|mutation with no effect:16-16|mutation decreasing interaction strength:31-31|mutation decreasing interaction strength:35-35|mutation decreasing interaction strength:42-42 | 1 | 2 | psi-mi:"MI:0396"(predetermined participant) | psi-mi:"MI:0396"(predetermined participant) |
Most frequent
| #ID(s) interactor A | ID(s) interactor B | Alt. ID(s) interactor A | Alt. ID(s) interactor B | Alias(es) interactor A | Alias(es) interactor B | Interaction detection method(s) | Publication 1st author(s) | Publication Identifier(s) | Taxid interactor A | Taxid interactor B | Interaction type(s) | Source database(s) | Interaction identifier(s) | Confidence value(s) | Expansion method(s) | Biological role(s) interactor A | Biological role(s) interactor B | Experimental role(s) interactor A | Experimental role(s) interactor B | Type(s) interactor A | Type(s) interactor B | Xref(s) interactor A | Xref(s) interactor B | Interaction Xref(s) | Annotation(s) interactor A | Annotation(s) interactor B | Interaction annotation(s) | Host organism(s) | Interaction parameter(s) | Creation date | Update date | Checksum(s) interactor A | Checksum(s) interactor B | Interaction Checksum(s) | Negative | Feature(s) interactor A | Feature(s) interactor B | Stoichiometry(s) interactor A | Stoichiometry(s) interactor B | Identification method participant A | Identification method participant B | count | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 146 | uniprotkb:P04578 | uniprotkb:P01889 | intact:EBI-6163496|uniprotkb:O09779 | intact:EBI-1046513|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793 | psi-mi:env_hv1h2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) | psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym) | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | Jager et al. (2012) | imex:IM-17346|pubmed:22190034|psi-mi:"MI:0007" | taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0914"(association) | psi-mi:"MI:0469"(IntAct) | intact:EBI-6174316|imex:IM-17346-4 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:5ZCX|rcsb pdb:5GHW|rcsb pdb:5H0N|rcsb pdb:5KA5|rcsb pdb:5KA6|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019068"(virion assembly)|go:"GO:0019082"(viral protein processing)|rcsb pdb:1MZI|go:"GO:0019058"(viral life cycle)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:2MG1|rcsb pdb:2MG2|rcsb pdb:2MG3|rcsb pdb:4YDV|rcsb pdb:4ZTO|rcsb pdb:5C0R|rcsb pdb:5C0S|rcsb pdb:3DRO|rcsb pdb:5IVX|rcsb pdb:5X08|dip:DIP-58525N|reactome:R-HSA-1462054|reactome:R-HSA-162588|reactome:R-HSA-171286|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-5621480|interpro:IPR037527|rcsb pdb:1FAV|rcsb pdb:3J70|rcsb pdb:5CMU|rcsb pdb:5CMZ|rcsb pdb:5CN0|go:"GO:0042802"(identical protein binding)|interpro:IPR036377|rcsb pdb:5DD0|rcsb pdb:5CIL|rcsb pdb:5CIN|rcsb pdb:3MNZ|rcsb pdb:5HM1|rcsb pdb:5NWU|rcsb pdb:5YB4|rcsb pdb:5Z0W|rcsb pdb:6BXQ|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019012"(virion)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|rcsb pdb:5BN0|mint:P04578|rcsb pdb:2NY7|rcsb pdb:6MQC|rcsb pdb:6MQE|rcsb pdb:6MQM|rcsb pdb:6MQR|rcsb pdb:6MQS|rcsb pdb:6N16|rcsb pdb:6NCP|rcsb pdb:6PSA|rcsb pdb:6SNC|rcsb pdb:6SND|rcsb pdb:6SNE|rcsb pdb:5TKJ|rcsb pdb:5TKK|rcsb pdb:5WDF|rcsb pdb:6BXP|rcsb pdb:6DLN|rcsb pdb:5NVP|rcsb pdb:5NWW|rcsb pdb:5YB2|rcsb pdb:5YB3|rcsb pdb:5YC0|rcsb pdb:6B9K|rcsb pdb:6DE7|rcsb pdb:3D0V|rcsb pdb:2ME1|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|rcsb pdb:1AIK|rcsb pdb:1DF4|rcsb pdb:1DF5|rcsb pdb:1DLB|rcsb pdb:1G9M|rcsb pdb:1GC1|rcsb pdb:1GZL|rcsb pdb:1K33|rcsb pdb:1K34|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:1RZJ|rcsb pdb:2CMR|rcsb pdb:2PV6|rcsb pdb:2XRA|rcsb pdb:3DNL|rcsb pdb:3DNN|rcsb pdb:3DNO|rcsb pdb:3IDX|rcsb pdb:3IDY|rcsb pdb:3TYG|rcsb pdb:3VIE|refseq:NP_057856.1|rcsb pdb:5HFL|rcsb pdb:4JPJ|rcsb pdb:4JPK|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell) | rcsb pdb:3VCL|rcsb pdb:4U1H|rcsb pdb:4U1K|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|ensembl:ENSG00000234745|ensembl:ENSP00000399168|ensembl:ENST00000412585|refseq:NP_005505.2|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0006952"(defense response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|mint:P01889|rcsb pdb:6MTL|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|rcsb pdb:6PYJ | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | comment:"DIP protein P04578 original sequence version: 85"|comment:"DIP protein P04578 original sequence version: 140" | author-confidence:0.75 | figure legend:suppl. data 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) | - | 2012/07/09 | 2019/11/11 | rogid:0cs6c9Wi6DV3vHjKBSlqRJ8keHk11706 | rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606 | intact-crc:213AE67A87EADC94|rigid:58CQMT8iUJmei4cC87auYqYHfbE | False | mutation:53-53,94-94,192-192,215-215,224-224,346-346,470-470,580-580("MI:0118")|tandem tag:c-c("MI:0677") | - | - | - | psi-mi:"MI:0102"(sequence tag identification) | psi-mi:"MI:0102"(sequence tag identification) | 10 |
| 145 | uniprotkb:P03421 | intact:EBI-11473246 | intact:EBI-6930954|uniprotkb:P90196 | intact:EBI-11473188|intact:EBI-11473232|intact:EBI-11473238|intact:EBI-11473244|intact:EBI-11473268|intact:EBI-11473270|intact:EBI-11473290|intact:EBI-11473258|intact:EBI-11473282|intact:EBI-11473294 | psi-mi:phosp_hrsva(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) | psi-mi:h2a2a_mesau_protein(display_short)|psi-mi:EBI-11473246(display_long) | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | Munday et al. (2015) | pubmed:25355874|imex:IM-25896 | taxid:11259(hrsva)|taxid:11259(human respiratory sy) | taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)") | psi-mi:"MI:0914"(association) | psi-mi:"MI:1335"(HPIDb) | intact:EBI-11364790|imex:IM-25896-3 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:6PZK|interpro:IPR003487(Phosphoprotein, pneumoviral)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0019012"(virion)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:4UCB|rcsb pdb:6G0Y | - | - | - | comment:similar to Q6GSS7 H2A2A_MOUSE|comment:similar to P17932 RL32P_MOUSE|comment:similar to Q9Z130 HNRDL_MOUSE|comment:similar to P06151 LDHA_MOUSE|comment:similar to P62984 RL40_MOUSE|comment:similar to P62918 RL8_MOUSE|comment:similar to P62900 RL31_MOUSE | figure legend:S2|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) | - | 2015/10/29 | 2019/02/21 | rogid:JX7IyIOgX+Hy/wIRNw4pGOQrXzs11259 | - | - | False | enhanced green fluorescent protein tag:32-32 | - | - | - | psi-mi:"MI:0102"(sequence tag identification) | psi-mi:"MI:0102"(sequence tag identification) | 9 |
| 202 | uniprotkb:P28887 | intact:EBI-11473246 | intact:EBI-11364737|uniprotkb:O41356|uniprotkb:O41355|uniprotkb:P90197|uniprotkb:Q82021 | intact:EBI-11473188|intact:EBI-11473232|intact:EBI-11473238|intact:EBI-11473244|intact:EBI-11473268|intact:EBI-11473270|intact:EBI-11473290|intact:EBI-11473258|intact:EBI-11473282|intact:EBI-11473294 | psi-mi:l_hrsva(display_long)|uniprotkb:L(gene name)|psi-mi:L(display_short)|uniprotkb:Large structural protein(gene name synonym)|uniprotkb:Replicase(gene name synonym)|uniprotkb:Transcriptase(gene name synonym) | psi-mi:h2a2a_mesau_protein(display_short)|psi-mi:EBI-11473246(display_long) | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | Munday et al. (2015) | pubmed:25355874|imex:IM-25896 | taxid:11259(hrsva)|taxid:11259(human respiratory sy) | taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)") | psi-mi:"MI:0914"(association) | psi-mi:"MI:1335"(HPIDb) | intact:EBI-11364735|imex:IM-25896-1 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | interpro:IPR016269(RNA-directed RNA polymerase, paramyxovirus)|go:"GO:0039689"(negative stranded viral RNA replication)|interpro:IPR039736|rcsb pdb:6PZK|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0019012"(virion)|go:"GO:0005524"(ATP binding)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|interpro:IPR014023(RNA-directed RNA polymerase catalytic)|interpro:IPR025786|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|interpro:IPR026890 | - | - | - | comment:similar to Q6GSS7 H2A2A_MOUSE|comment:similar to P17932 RL32P_MOUSE|comment:similar to Q9Z130 HNRDL_MOUSE|comment:similar to P06151 LDHA_MOUSE|comment:similar to P62984 RL40_MOUSE|comment:similar to P62918 RL8_MOUSE|comment:similar to P62900 RL31_MOUSE | figure legend:S1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:10036(mesau-bhk21)|taxid:10036(Mesocricetus auratus_BHK21) | - | 2015/10/29 | 2019/02/21 | rogid:SzpLo1VW6p3PDK0g+ErGsMEA+BU11259 | - | - | False | enhanced green fluorescent protein tag:1738-1739 | - | - | - | psi-mi:"MI:0102"(sequence tag identification) | psi-mi:"MI:0102"(sequence tag identification) | 5 |
| 46 | uniprotkb:A0A1L8G4G8 | uniprotkb:B1WBE0 | intact:EBI-3645294 | intact:EBI-3510530 | psi-mi:a0a1l8g4g8_xenla(display_long)|uniprotkb:hdlbp.S(gene name)|psi-mi:hdlbp.S(display_short)|uniprotkb:XELAEV_18029889mg(orf name) | psi-mi:b1wbe0_xenla(display_long)|uniprotkb:eprs1.S(gene name)|psi-mi:eprs1.S(display_short)|uniprotkb:LOC100158438(gene name synonym)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)|uniprotkb:eprs(gene name synonym)|uniprotkb:eprs1(gene name synonym) | psi-mi:"MI:0029"(cosedimentation through density gradient) | Gache et al. (2010) | pubmed:20174651|imex:IM-17228 | taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") | taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") | psi-mi:"MI:0403"(colocalization) | psi-mi:"MI:0469"(IntAct) | intact:EBI-3645151|imex:IM-17228-3 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | interpro:IPR036612|uniprotkb:Q7ZTN2(uniprot-removed-ac)|go:"GO:0003723"(RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:XP_018121321.1|refseq:XP_018121322.1 | go:"GO:0005737"(cytoplasm)|go:"GO:0005524"(ATP binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|refseq:NP_001121346.1|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020061|interpro:IPR020058|interpro:IPR020059|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR020056|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR000738(WHEP-TRS)|interpro:IPR033721|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR036282|interpro:IPR036621 | - | - | - | figure legend:Table S1|caution:"The participant EBI-3645738() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) | - | 2011/02/14 | 2018/02/26 | rogid:bD8k16jeBUqq4mj5k0OvlJRS6EQ8355 | rogid:cX8k4MBg+cf51rz5jkJKvwZH5VM8355 | intact-crc:0F5278A54AD61E9D | False | - | - | - | - | psi-mi:"MI:0082"(peptide massfingerprinting) | psi-mi:"MI:0082"(peptide massfingerprinting) | 4 |
| 593 | uniprotkb:Q9WMX2-PRO_0000037545 | uniprotkb:P22736 | intact:EBI-9028517 | intact:EBI-721550|uniprotkb:Q15627|uniprotkb:Q53Y00|uniprotkb:Q6IBU8|uniprotkb:B4DML7 | psi-mi:q9wmx2-pro_0000037545(display_long) | psi-mi:nr4a1_human(display_long)|uniprotkb:Nuclear hormone receptor NUR/77(gene name synonym)|uniprotkb:Testicular receptor 3(gene name synonym)|uniprotkb:Orphan nuclear receptor HMR(gene name synonym)|uniprotkb:Early response protein NAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR3(gene name synonym)|uniprotkb:ST-59(gene name synonym)|uniprotkb:GFRP1(gene name synonym)|uniprotkb:HMR(gene name synonym)|uniprotkb:NAK1(gene name synonym)|uniprotkb:NR4A1(gene name)|psi-mi:NR4A1(display_short) | psi-mi:"MI:0018"(two hybrid) | de et al. (2008) | pubmed:18985028|imex:IM-25957 | taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0915"(physical association) | psi-mi:"MI:1335"(HPIDb) | intact:EBI-9078372|imex:IM-25957-623 | intact-miscore:0.37 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | intact:EBI-710918(chain-parent) | rcsb pdb:4JGV|rcsb pdb:4KZI|rcsb pdb:4KZJ|rcsb pdb:4KZM|refseq:NP_002126.2|refseq:NP_775180.1|ensembl:ENSG00000123358|interpro:IPR003071(Orphan nuclear receptor, HMR type)|interpro:IPR003070(Orphan nuclear receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:2QW4|go:"GO:0042025"(host cell nucleus)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005829"(cytosol)|refseq:XP_005268881.1|go:"GO:0005634"(nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|reactome:R-HSA-198693|reactome:R-HSA-383280|reactome:R-HSA-5674400|refseq:XP_006719426.1|refseq:XP_006719427.1|ensembl:ENSP00000243050|ensembl:ENSP00000353427|ensembl:ENSP00000378301|ensembl:ENSP00000378302|ensembl:ENSP00000449539|ensembl:ENSP00000449587|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0071376"(cellular response to corticotropin-releasing hormone stimulus)|rcsb pdb:4RE8|rcsb pdb:4REE|rcsb pdb:4REF|rcsb pdb:4WHF|rcsb pdb:4WHG|rcsb pdb:4RZE|rcsb pdb:4RZF|rcsb pdb:4RZG|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0000790"(nuclear chromatin)|go:"GO:0005739"(mitochondrion)|rcsb pdb:6LC1|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0035259"(glucocorticoid receptor binding)|interpro:IPR035500|mint:P22736|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|dip:DIP-40392N|refseq:NP_001189162.1|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000243050|ensembl:ENST00000360284|ensembl:ENST00000394824|ensembl:ENST00000394825|ensembl:ENST00000548232|ensembl:ENST00000550082|rcsb pdb:3V3E|rcsb pdb:3V3Q | - | - | comment:"DIP protein P22736 original sequence version: 156" | figure legend:Supp data S1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) | - | 2013/11/25 | 2017/09/02 | rogid:fOz8NHDQRviw5MpyTRtVblSks5c333284 | rogid:yocf+C94vprIeNXXB89p3tqzW/c9606 | intact-crc:43DDC491C360014F|rigid:W+BpLyAZ0FD2VlfvTvO9sa1haEM | False | - | - | - | - | psi-mi:"MI:0078"(nucleotide sequence identification) | psi-mi:"MI:0078"(nucleotide sequence identification) | 4 |
| 1 | chebi:"CHEBI:16618" | uniprotkb:P01889 | intact:EBI-1257125 | intact:EBI-1046513|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793 | psi-mi:1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate(display_short)|psi-mi:"CHEBI:16618"(display_long) | psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym) | psi-mi:"MI:0096"(pull down) | Catimel et al. (2009) | pubmed:19463016|imex:IM-17246 | taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0914"(association) | psi-mi:"MI:0469"(IntAct) | intact:EBI-4289959|imex:IM-17246-2 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0328"(small molecule) | psi-mi:"MI:0326"(protein) | - | rcsb pdb:3VCL|rcsb pdb:4U1H|rcsb pdb:4U1K|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:6AVG|ensembl:ENSG00000234745|ensembl:ENSP00000399168|ensembl:ENST00000412585|refseq:NP_005505.2|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0006952"(defense response)|go:"GO:0016045"(detection of bacterium)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:2H6P|rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5INC|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6D29|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTM|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|mint:P01889|rcsb pdb:6MTL|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|rcsb pdb:6PYJ | - | - | - | figure legend:Supplementary Table 1 and 2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:-1(in vitro)|taxid:-1(In vitro) | - | 2011/06/16 | 2019/11/11 | - | rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606 | intact-crc:DE189F805D31868C | False | - | - | - | - | psi-mi:"MI:0427"(Identification by mass spectrometry) | psi-mi:"MI:0427"(Identification by mass spectrometry) | 3 |
| 71 | uniprotkb:A5XAW2 | uniprotkb:Q8AWF5 | intact:EBI-3511040 | intact:EBI-1000337|uniprotkb:Q6NRM2 | psi-mi:a5xaw2_xenla(display_long)|uniprotkb:KHC(gene name)|psi-mi:KHC(display_short) | psi-mi:ndc80_xenla(display_long)|uniprotkb:ndc80(gene name)|psi-mi:ndc80(display_short)|uniprotkb:kntc2(gene name synonym)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym) | psi-mi:"MI:0029"(cosedimentation through density gradient) | Gache et al. (2010) | pubmed:20174651|imex:IM-17228 | taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") | taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") | psi-mi:"MI:0403"(colocalization) | psi-mi:"MI:0469"(IntAct) | intact:EBI-3511241|imex:IM-17228-2 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0497"(neutral component) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|go:"GO:0005874"(microtubule)|go:"GO:0005524"(ATP binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961 | interpro:IPR005550(HEC/Ndc80p)|go:"GO:0000777"(condensed chromosome kinetochore)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007052"(mitotic spindle organization)|refseq:NP_001082372.1|interpro:IPR038273|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0000776"(kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR040967|refseq:XP_018103626.1 | - | - | - | figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) | - | 2011/02/14 | 2019/01/23 | rogid:QglBQVdrfKZyyiGImgNFVONJ5D08355 | rogid:fbrLPmNbZRHqOGCcZZUpNZ0cJx48355 | intact-crc:F4752A99DA7D05A5 | False | - | - | - | - | psi-mi:"MI:0082"(peptide massfingerprinting) | psi-mi:"MI:0082"(peptide massfingerprinting) | 3 |
| 90 | uniprotkb:O15372 | uniprotkb:O15372 | intact:EBI-709735 | intact:EBI-709735 | psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) | psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | Sowa et al. (2009) | pubmed:19615732|imex:IM-12079 | taxid:9606(human)|taxid:9606(Homo sapiens) | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0915"(physical association) | psi-mi:"MI:0469"(IntAct) | intact:EBI-2510472|imex:IM-12079-55 | intact-miscore:0.40 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0016020"(membrane)|ensembl:ENST00000521861|mint:O15372|go:"GO:0003723"(RNA binding)|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000147677|ensembl:ENSP00000429931|dip:DIP-33689N|rcsb pdb:3J8B|rcsb pdb:3J8C|go:"GO:0070062"(extracellular exosome)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR037518|interpro:IPR027524|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_003747.1|interpro:IPR000555(Mov34/MPN/PAD-1)|go:"GO:0006413"(translational initiation) | go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0016020"(membrane)|ensembl:ENST00000521861|mint:O15372|go:"GO:0003723"(RNA binding)|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000147677|ensembl:ENSP00000429931|dip:DIP-33689N|rcsb pdb:3J8B|rcsb pdb:3J8C|go:"GO:0070062"(extracellular exosome)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0008237"(metallopeptidase activity)|interpro:IPR037518|interpro:IPR027524|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006446"(regulation of translational initiation)|refseq:NP_003747.1|interpro:IPR000555(Mov34/MPN/PAD-1)|go:"GO:0006413"(translational initiation) | psi-mi:"MI:0469"(intact) | comment:"DIP protein O15372 original sequence version: 74"|comment:"DIP protein O15372 original sequence version: 89"|comment:"DIP protein O15372 original sequence version: 118" | comment:"DIP protein O15372 original sequence version: 74"|comment:"DIP protein O15372 original sequence version: 89"|comment:"DIP protein O15372 original sequence version: 118" | figure legend:submitted by author|caution:"The participant EBI-366647(O75822) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510460(B0QY89) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366617(Q14152) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2509449() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353901(Q7L2H7) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347740(P60228) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-348169(P67870) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510446(P61221) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347451(P19784) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-347804(P68400) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366632(O75821) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353741(Q99613) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-354047(Q13347) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2507547() was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510474(Q5JT00) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510442(Q9BX72) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-354344(Q9UBQ5) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-2510439(O95065) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-353818(O15371) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|caution:"The participant EBI-366696(P55884) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) | - | 2009/12/18 | 2017/12/08 | rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 | rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 | intact-crc:20F800B7B4841EDE|rigid:i3zuCcUqSmEYgzLsmrtzHSPk68M | False | ha tag:n-n|flag tag:n-n | - | - | - | psi-mi:"MI:0102"(sequence tag identification) | psi-mi:"MI:0102"(sequence tag identification) | 3 |
| 113 | uniprotkb:P00895 | uniprotkb:P37246 | intact:EBI-1118772|uniprotkb:P78249 | intact:EBI-1123174|uniprotkb:P77341|uniprotkb:Q2M630|uniprotkb:Q2MCF8 | psi-mi:trpe_ecoli(display_long)|uniprotkb:trpE(gene name)|psi-mi:trpE(display_short)|uniprotkb:b1264(locus name)|uniprotkb:JW1256(locus name) | psi-mi:insi_ecoli(display_long)|uniprotkb:insI1(gene name)|psi-mi:insI1(display_short)|uniprotkb:b0256(locus name)|uniprotkb:JW0246(locus name)|uniprotkb:insI2(gene name)|psi-mi:insI2(display_short)|uniprotkb:b1404(locus name)|uniprotkb:JW1401(locus name)|uniprotkb:insI3(gene name)|psi-mi:insI3(display_short)|uniprotkb:b4284(locus name)|uniprotkb:JW4244(locus name) | psi-mi:"MI:0096"(pull down) | Arifuzzaman et al. (2006) | pubmed:16606699 | taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") | taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") | psi-mi:"MI:0914"(association) | psi-mi:"MI:0469"(IntAct) | intact:EBI-1139361 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | interpro:IPR006805(Anthranilate synthase component I, N-terminal)|interpro:IPR015890(Chorismate binding, C-terminal)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|refseq:WP_001194582.1|go:"GO:0004049"(anthranilate synthase activity)|go:"GO:0000162"(tryptophan biosynthetic process)|refseq:NP_415780.1|interpro:IPR005801(Anthranilate synthase component I and chorismate binding protein)|interpro:IPR019999|interpro:IPR005257(Anthranilate synthase component I, TrpE) | refseq:AP_000909.1|refseq:AP_002030.1|refseq:AP_004775.1|refseq:NP_415922.1|refseq:NP_418704.1|go:"GO:0003677"(DNA binding)|go:"GO:0004803"(transposase activity)|go:"GO:0015074"(DNA integration)|go:"GO:0006313"(transposition, DNA-mediated)|refseq:YP_001294740.1|interpro:IPR009057(Homeodomain-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR001598(Transposase, IS30, conserved site) | - | - | - | - | taxid:316407(ecow3)|taxid:316407("Escherichia coli (strain K12 / W3110 / ATCC 27325 / DSM 5911)") | - | 2006/10/24 | 2014/10/16 | rogid:OZ1/ZKSrXlVRyfE6EpNIE+aF0l483333 | rogid:3GKoT+3fbkbyHbtUS6vI82OVIXk83333 | intact-crc:4A6897CFD632EDDF|rigid:cYdXr/hTy/Xkidhh/+vh6KqSFM0 | False | his tag:?-? | - | 1 | 1 | psi-mi:"MI:0427"(Identification by mass spectrometry) | psi-mi:"MI:0427"(Identification by mass spectrometry) | 3 |
| 147 | uniprotkb:P04578 | uniprotkb:P10321 | intact:EBI-6163496|uniprotkb:O09779 | intact:EBI-1051396|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063 | psi-mi:env_hv1h2(display_long)|uniprotkb:env(gene name)|psi-mi:env(display_short)|uniprotkb:Env polyprotein(gene name synonym) | psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | Jager et al. (2012) | imex:IM-17346|pubmed:22190034|psi-mi:"MI:0007" | taxid:11706(hv1h2)|taxid:11706("Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)") | taxid:9606(human)|taxid:9606(Homo sapiens) | psi-mi:"MI:0914"(association) | psi-mi:"MI:0469"(IntAct) | intact:EBI-6174316|imex:IM-17346-4 | intact-miscore:0.35 | psi-mi:"MI:1060"(spoke expansion) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0499"(unspecified role) | psi-mi:"MI:0496"(bait) | psi-mi:"MI:0498"(prey) | psi-mi:"MI:0326"(protein) | psi-mi:"MI:0326"(protein) | rcsb pdb:5ZCX|rcsb pdb:5GHW|rcsb pdb:5H0N|rcsb pdb:5KA5|rcsb pdb:5KA6|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019068"(virion assembly)|go:"GO:0019082"(viral protein processing)|rcsb pdb:1MZI|go:"GO:0019058"(viral life cycle)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1903908"(positive regulation of plasma membrane raft polarization)|go:"GO:1903911"(positive regulation of receptor clustering)|rcsb pdb:2MG1|rcsb pdb:2MG2|rcsb pdb:2MG3|rcsb pdb:4YDV|rcsb pdb:4ZTO|rcsb pdb:5C0R|rcsb pdb:5C0S|rcsb pdb:3DRO|rcsb pdb:5IVX|rcsb pdb:5X08|dip:DIP-58525N|reactome:R-HSA-1462054|reactome:R-HSA-162588|reactome:R-HSA-171286|reactome:R-HSA-173107|reactome:R-HSA-175474|reactome:R-HSA-5621480|interpro:IPR037527|rcsb pdb:1FAV|rcsb pdb:3J70|rcsb pdb:5CMU|rcsb pdb:5CMZ|rcsb pdb:5CN0|go:"GO:0042802"(identical protein binding)|interpro:IPR036377|rcsb pdb:5DD0|rcsb pdb:5CIL|rcsb pdb:5CIN|rcsb pdb:3MNZ|rcsb pdb:5HM1|rcsb pdb:5NWU|rcsb pdb:5YB4|rcsb pdb:5Z0W|rcsb pdb:6BXQ|go:"GO:0044175"(host cell endosome membrane)|go:"GO:0055036"(virion membrane)|go:"GO:0019012"(virion)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|rcsb pdb:5BN0|mint:P04578|rcsb pdb:2NY7|rcsb pdb:6MQC|rcsb pdb:6MQE|rcsb pdb:6MQM|rcsb pdb:6MQR|rcsb pdb:6MQS|rcsb pdb:6N16|rcsb pdb:6NCP|rcsb pdb:6PSA|rcsb pdb:6SNC|rcsb pdb:6SND|rcsb pdb:6SNE|rcsb pdb:5TKJ|rcsb pdb:5TKK|rcsb pdb:5WDF|rcsb pdb:6BXP|rcsb pdb:6DLN|rcsb pdb:5NVP|rcsb pdb:5NWW|rcsb pdb:5YB2|rcsb pdb:5YB3|rcsb pdb:5YC0|rcsb pdb:6B9K|rcsb pdb:6DE7|rcsb pdb:3D0V|rcsb pdb:2ME1|go:"GO:0005198"(structural molecule activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|interpro:IPR000328(Envelope Polyprotein GP41)|interpro:IPR000777(Envelope glycoprotein GP120)|rcsb pdb:1AIK|rcsb pdb:1DF4|rcsb pdb:1DF5|rcsb pdb:1DLB|rcsb pdb:1G9M|rcsb pdb:1GC1|rcsb pdb:1GZL|rcsb pdb:1K33|rcsb pdb:1K34|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:1RZJ|rcsb pdb:2CMR|rcsb pdb:2PV6|rcsb pdb:2XRA|rcsb pdb:3DNL|rcsb pdb:3DNN|rcsb pdb:3DNO|rcsb pdb:3IDX|rcsb pdb:3IDY|rcsb pdb:3TYG|rcsb pdb:3VIE|refseq:NP_057856.1|rcsb pdb:5HFL|rcsb pdb:4JPJ|rcsb pdb:4JPK|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell) | go:"GO:0042605"(peptide antigen binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-1236974|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016020"(membrane)|go:"GO:0046977"(TAP binding)|go:"GO:0009986"(cell surface)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0016032"(viral process)|reactome:R-HSA-2172127|rcsb pdb:6JTO|interpro:IPR036179|interpro:IPR037055|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|rcsb pdb:1IM9|rcsb pdb:1QQD|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1EFX|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|reactome:R-HSA-6798695|mint:P10321|ensembl:ENSG00000204525|ensembl:ENSP00000365402|ensembl:ENST00000376228|refseq:NP_002108.4 | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | comment:"DIP protein P04578 original sequence version: 85"|comment:"DIP protein P04578 original sequence version: 140" | comment:"DIP protein P30504 original sequence version: 126"|author-confidence:0.82 | figure legend:suppl. data 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation | taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) | - | 2012/07/09 | 2019/11/11 | rogid:0cs6c9Wi6DV3vHjKBSlqRJ8keHk11706 | rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 | intact-crc:213AE67A87EADC94|rigid:58CQMT8iUJmei4cC87auYqYHfbE | False | mutation:53-53,94-94,192-192,215-215,224-224,346-346,470-470,580-580("MI:0118")|tandem tag:c-c("MI:0677") | - | - | - | psi-mi:"MI:0102"(sequence tag identification) | psi-mi:"MI:0102"(sequence tag identification) | 3 |